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Culture-proven Endogenous Endophthalmitis: Clinical Features And Visual Acuity Outcomes.

Vivian Schiedler, Ingrid U. Scott, Harry W. Flynn, Janet L. Davis, Matthew S. Benz, Darlene Miller
Published 2004 · Medicine
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PURPOSE To investigate clinical features and visual acuity outcomes associated with endogenous endophthalmitis. DESIGN Retrospective, observational case series. METHODS Twenty-one eyes of 21 patients treated at Bascom Palmer Eye Institute for culture-proven endogenous endophthalmitis between 1996 and 2002 were reviewed. RESULTS Patients were followed a mean of 3 months (range, 1 to 12 months). Fungal isolates occurred in 13 eyes (62%), gram-positive isolates in 7 (33%), and gram-negative isolates in 1 (5%). Twelve patients (57%) were hospitalized at the time of diagnosis and 6 patients (29%) died within 2 months of diagnosis. Initial treatment included tap and injection of intravitreal medication in 10 eyes (48%) and pars plana vitrectomy with injection of intravitreal medication in 11 eyes (52%). Final visual outcomes were obtainable for 18 eyes (two patients died within 10 days of diagnosis, and one patient was lost to follow-up). Eight (44%) of these 18 eyes achieved a visual acuity of 20/400 or better and 10 (56%) of 18 eyes achieved a visual acuity worse than 20/400, including 3 that were either enucleated or eviscerated. Three eyes with Aspergillus endophthalmitis had worse visual outcomes than eyes with either Candida (P =.036) or bacterial endophthalmitis (P =.024). CONCLUSIONS Compared with published series of postoperative or post-traumatic endophthalmitis, patients with endogenous endophthalmitis are more likely to have fungal isolates with a predominance of Candida albicans. Endogenous endophthalmitis is generally associated with high mortality and poor visual acuity outcomes, particularly when caused by more virulent species such as Aspergillus.



This paper is referenced by
10.1007/978-1-4419-0374-7_36
Management of Endogenous Endophthalmitis
Kapil G. Kapoor (2010)
10.1186/s12886-020-01418-9
Endogenous Endophthalmitis: yield of the diagnostic evaluation
Kathleen A. Regan (2020)
10.3947/ic.2017.49.4.286
Infective Endocarditis Presenting as Endogenous Endophthalmitis Secondary to Streptococcus agalactiae in a Healthy Adult: Case Report and Literature Review
Yu Ra Sim (2017)
10.1016/j.jcrs.2006.11.031
Posttraumatic Aspergillus terreus endophthalmitis masquerading as dispersed lens fragments.
Nader Moinfar (2007)
10.1371/journal.pone.0227442
The impact of diabetes mellitus medication on the incidence of endogenous endophthalmitis
Ke-Hung Chien (2020)
10.3947/ic.2018.50.3.238
Analysis of Klebsiella as a Prognostic Factor of Ocular Outcomes in Endogenous Endophthalmitis with Decision Tree Analysis
Hyejin Jung (2018)
10.1111/jsap.12136
Endogenous endophthalmitis caused by Enterococcus faecalis in a cat
E. J. Van Donzel (2014)
10.1155/2015/897245
ESBL E. coli Urosepsis Resulting in Endogenous Panophthalmitis Requiring Evisceration of the Eye in a Diabetic Patient
Tejaswini Arunachala Murthy (2015)
10.1007/s00417-017-3760-4
59 eyes with endogenous endophthalmitis– causes, outcomes and mortality in a Danish population between 2000 and 2016
Søren Solborg Bjerrum (2017)
10.1007/978-981-10-5260-6_18
Endophthalmitis Caused by Methicillin-Resistant Staphylococcus aureus (MRSA)
Nidhi Relhan (2008)
10.1007/978-3-319-29231-1_3
Microbiologic Diagnosis in Endophthalmitis
Darlene Miller (2016)
10.3928/15428877-20111201-01
Irido-lenticular abscess as the initial sign of Candida albicans endogenous endophthalmitis.
Puneet S. Braich (2011)
10.1159/000431195
Ocular Infection: Endophthalmitis.
Stephen G. Schwartz (2016)
10.1097/IAE.0000000000000126
PSEUDALLESCHERIA ENDOPHTHALMITIS: FOUR CASES OVER 15 YEARS IN QUEENSLAND, AUSTRALIA, AND A REVIEW OF THE LITERATURE
Thomas P Moloney (2014)
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Caroline François-Fiquet (2012)
10.1038/eye.2017.92
Clinical features and prognostic factors of Klebsiella endophthalmitis—10-year experience in an endemic region
Carol Y. Chung (2017)
ASPERGILLUS ENDOPHTHALMITIS: PARS PLANA VITRECTOMY IS AN ALTERNATIVE
Pakhee Aggarwal (2009)
La endoftalmitis endógena por Candida, un marcador pronóstico
Isabel Ambou (2018)
10.1097/IAE.0b013e3181a3b7a1
ENDOGENOUS ENDOPHTHALMITIS CAUSED BY METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS (MRSA)
Thomas Ness (2009)
Endogenous Endophthalmitis – A Review
Aji Sam Mathews (2011)
10.3109/09273948.2015.1115080
Outcomes of Primary Transconjunctival 23-Gauge Vitrectomy in the Diagnosis and Treatment of Presumed Endogenous Fungal Endophthalmitis
Antony William (2017)
10.5114/ko.2016.71715
Diagnostic challenges in presumably endogeneous fungal endophthalmitis.
Alicja Burek (2016)
10.1016/j.survophthal.2017.05.001
Exudative retinal detachment.
Radgonde Amer (2017)
10.1097/IIO.0b013e31803778f7
Endogenous Bacterial and Fungal Endophthalmitis
Stephen Robert Smith (2007)
10.1007/s10792-007-9111-4
Endogenous endophthalmitis complicating Klebsiella pneumoniae liver abscess in Europe: case report
Edison Mutsinzi Karama (2007)
10.1007/978-3-319-62606-2
Orbital Cellulitis and Periorbital Infections
M. T. Yen (2018)
10.4067/S0716-10182013000500009
Endoftalmitis endógenas: revisión de una serie de casos y revaloración de una entidad ocular grave
María Ángeles Asencio-Egea (2013)
10.1586/14787210.4.4.675
Endogenous Candida endophthalmitis
Ahmed Sallam (2006)
10.1586/eop.10.52
Severe bacterial endophthalmitis: towards improving clinical outcomes
Billy D. Novosad (2010)
10.1177/1120672118815105
The role of pars plana vitrectomy in the management of fungal endogenous endophthalmitis
Hande Celiker (2018)
10.3109/09273940903494717
Endogenous Endophthalmitis: A 10-year Review of Culture-positive Cases in Northern China
Han Zhang (2010)
10.1007/s10096-007-0443-9
Fungal endophthalmitis in a tertiary care cancer center: a review of 23 cases
Gregory A. Lamaris (2007)
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