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Epidemiological Surveillance Of Mesothelioma Mortality In Italy.

L. Fazzo, G. Minelli, M. De Santis, C. Bruno, A. Zona, S. Conti, P. Comba
Published 2018 · Medicine

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BACKGROUND Malignant mesothelioma (MM) is causally linked to asbestos exposure with an estimated etiological fraction of 80% or more. METHODS Standardized rates of all mesothelioma (C45, ICD-10) and malignant pleural mesothelioma (C45.0, ICD-10) mortality in Italy were computed at national and regional levels, for the period 2003-2014. Standardized Mortality Ratios (SMRs, with 95% Confidence Intervals) were calculated for each of the 8047 Italian municipalities, for both diseases, with respect to Regional figures. A geographical clustering analysis at municipal level was performed, applying SatScan methods. RESULTS In Italy, 16,086 persons (about 1,340/year) died for MM, in analysed period. National Standardized rates of MM mortality are 3.65/100,000 in men and 1.09/100,000 in women, with an increasing annual trend, among male population. The highest rates were found in men from Northern Regions. Significant clusters (p < 0.10) were found corresponding to areas that hosted major asbestos-cement plants, naval shipyards, petrochemical plants and refineries. Furthermore, excesses were found corresponding to chemical and textile industries; the latter involving, particularly, female population. Excesses were found also in areas near the chrysotile mine of Balangero, and in Biancavilla, a town with a stone quarry contaminated by fluoro-edenitic fibres; an excess of MM mortality was observed among male population living in a minor island where a Navy shipyard is located. CONCLUSIONS Mortality for mesothelioma in Italy is still increasing, twenty-six years after the asbestos ban. Epidemiological surveillance of mesothelioma mortality allows to detect the temporal trend of the disease and highlights previously unknown or underestimated sources of asbestos exposure.
This paper references
The fibres with fluoro-edenitic composition in Biancavilla (Sicily, Italy): health impact and clues for environmental remediation.
P. Comba (2014)
The health impact of nonoccupational exposure to asbestos: what do we know?
M. Goldberg (2009)
Mortality among shipyard Coast Guard workers: a retrospective cohort study
S. Krstev (2007)
Asbestos-related cancers among 28,300 military servicemen in the Royal Norwegian Navy.
L. A. Strand (2010)
Urban mesothelioma: Is there an emerging risk of asbestos in place?
V. Ascoli (2004)
Mesothelioma mortality surveillance and asbestos exposure tracking in Italy.
L. Fazzo (2012)
Italian pool of asbestos workers cohorts: mortality trends of asbestos-related neoplasms after long time since first exposure
D. Ferrante (2017)
Determination of the concentration of asbestos minerals in highly contaminated mine tailings: An example from abandoned mine waste of Crètaz and Èmarese (Valle d’Aosta, Italy)
A. Gualtieri (2014)
Estimation of the global burden of mesothelioma deaths from incomplete national mortality data
Chimed-Ochir Odgerel (2017)
Ambient Asbestos Fiber Concentrations and Long-Term Trends in Pleural Mesothelioma Incidence between Urban and Rural Areas in the United States (1973-2012).
M. E. Glynn (2018)
[Territorial distribution of mortality from malignant tumors of the pleura in Italy].
M. Di Paola (1992)
Mesothelioma is a killer of urban men in Sweden
K. Hemminki (2003)
The epidemiology of malignant mesothelioma in women: gender differences and modalities of asbestos exposure
A. Marinaccio (2018)
Shipbuilding and mesothelioma in Monfalcone, Italy
C. Bianchi (2012)
Predictions of mortality from pleural mesothelioma in Italy: A model based on asbestos consumption figures supports results from age‐period‐cohort models
A. Marinaccio (2005)
Global Magnitude of Reported and Unreported Mesothelioma
Eun-Kee Park (2011)
Patologie asbesto-correlate e indicatori biologici di dose cumulativa in lavoratori di cantiere navale (1996-2015)
P. Barbieri (2016)
Excess of mesotheliomas after exposure to chrysotile in Balangero, Italy
D. Mirabelli (2008)
Malignant peritoneal mesothelioma: a review.
J. Kim (2017)
Analysis of latency time and its determinants in asbestos related malignant mesothelioma cases of the Italian register.
A. Marinaccio (2007)
Prevention of Asbestos-Related Disease in Countries Currently Using Asbestos
D. Marsili (2016)
[Asbestos exposure in the non-asbestos textile industry: the experience of the Lombardy Mesothelioma Registry].
C. Mensi (2007)
First and subsequent asbestos exposures in relation to mesothelioma and lung cancer mortality
E. Pira (2007)
Residual fibre lung burden among patients with pleural mesothelioma who have been occupationally exposed to asbestos
E. Merler (2016)
[Asbestos risk in the textile industry: braking systems on machinery used until the 1990's].
G. Chiappino (2005)
High incidence of mesothelioma in an English city without heavy industrial use of asbestos.
W. Hamilton (2004)
Global mesothelioma deaths reported to the World Health Organization between 1994 and 2008.
V. Delgermaa (2011)
Mode of action of fibrous amphiboles: the case of Biancavilla (Sicily, Italy).
Giulia Ballan (2014)
Mortality from cancer and other causes among Italian chrysotile asbestos miners
E. Pira (2017)
Pleural mesothelioma mortality and asbestos exposure mapping in Italy.
L. Fazzo (2012)
Knowns and unknowns on burden of disease due to chemicals: a systematic review
A. Prüss-Űstün (2011)
A historical cohort mortality study among shipyard workers in Genoa, Italy.
R. Puntoni (2001)

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