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Electron Transfer In Peptides And Proteins.

B. Giese, M. Graber, Meike Cordes
Published 2008 · Chemistry, Medicine

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Proteins and peptides use their amino acids as medium for electron-transfer reactions that occur either in single-step superexchange or in multistep hopping processes. Whereas the rate of the single-step electron transfer dramatically decreases with the distance, a hopping process is less distance dependent. Electron hopping is possible if amino acids carry oxidizable side chains, like the phenol group in tyrosine. These side chains become intermediate charge carriers. Because of the weak distance dependency of hopping processes, fast electron transfer over very long distances occurs in multistep reactions, as in the enzyme ribonucleotide reductase.
This paper references
10.1515/zna-1999-6-708
New Mechanism for Facile Charge Transport in Polypeptides
L. Baranov (1999)
10.1017/S0033583503003913
Electron tunneling through proteins.
H. Gray (2003)
10.1021/JP051592G
Effects of dipole moment, linkers, and chromophores at side chains on long-range electron transfer through helical peptides.
J. Watanabe (2005)
10.1016/J.CPLETT.2007.04.050
Theoretical investigation on intramolecular electron transfer in polypeptides
N. Santhanamoorthi (2007)
10.1073/PNAS.0408029102
Long-range electron transfer.
H. Gray (2005)
10.1002/anie.200705588
Influence of amino acid side chains on long-distance electron transfer in peptides: electron hopping via "stepping stones".
Meike Cordes (2008)
10.1021/JP0557969
Dissociative electron transfer in donor-peptide-acceptor systems: results for kinetic parameters from a density functional/polarizable continuum model.
V. Barone (2006)
10.1126/science.1158241
Tryptophan-Accelerated Electron Flow Through Proteins
Crystal Shih (2008)
10.1016/J.CHEMPHYS.2005.09.035
Theoretical study of long range electron transfer in Phthalimide–Peptide–Methyl Aminoacetate Model molecules
Xiang Gao (2006)
10.1038/46972
Natural engineering principles of electron tunnelling in biological oxidation–reduction
Christopher C. Page (1999)
10.1021/JA029787E
Anomalous distance dependence of electron transfer across peptide bridges.
S. Antonello (2003)
10.1021/JA043404Q
Electron transfer and catalytic control by the iron-sulfur clusters in a respiratory enzyme, E. coli fumarate reductase.
Janette M. Hudson (2005)
10.1016/J.CPLETT.2007.07.063
Long-range electron transfer across peptide chains with different secondary structures
Xiang Gao (2007)
10.1073/pnas.0711343105
Heme–copper oxidases use tunneling pathways
D. Beratan (2008)
10.1021/LA070175N
Study of electron transfer in ferrocene-labeled collagen-like peptides.
S. Dey (2007)
10.1021/JA0704434
Photoactive peptides for light-initiated tyrosyl radical generation and transport into ribonucleotide reductase.
Steven Y. Reece (2007)
10.1021/JP071599T
Conformational analysis of the electron-transfer kinetics across oligoproline peptides using N,N-dimethyl-1,4-benzenediamine donors and pyrene-1-sulfonyl acceptors.
Joseph B. Issa (2007)
10.1002/ADSC.200700605
Development of a model system for the study of long distance electron transfer in peptides
Meike Cordes (2008)
10.1021/JA055275Z
Electron flow in multicenter enzymes: theory, applications, and consequences on the natural design of redox chains.
C. Léger (2006)
10.1021/JA055927J
pH Rate profiles of FnY356-R2s (n = 2, 3, 4) in Escherichia coli ribonucleotide reductase: evidence that Y356 is a redox-active amino acid along the radical propagation pathway.
M. Seyedsayamdost (2006)
10.1002/CHIN.200332275
Radical Initiation in the Class I Ribonucleotide Reductase: Long-Range Proton-Coupled Electron Transfer?
J. Stubbe (2003)
10.1021/JA057776Q
Site-specific replacement of Y356 with 3,4-dihydroxyphenylalanine in the beta2 subunit of E. coli ribonucleotide reductase.
M. Seyedsayamdost (2006)
10.1016/J.CHEMPHYS.2006.01.010
Electron transfer across α-helical peptides: Potential influence of molecular dynamics
H. S. Mandal (2006)
10.1021/CR020421U
Radical initiation in the class I ribonucleotide reductase: long-range proton-coupled electron transfer?
J. Stubbe (2003)
10.1126/SCIENCE.1134862
Coupling Coherence Distinguishes Structure Sensitivity in Protein Electron Transfer
T. Prytkova (2007)
10.1016/J.CBPA.2003.08.005
Mechanism for electron transfer within and between proteins.
Christopher C. Page (2003)
10.1021/JA0685607
Forward and reverse electron transfer with the Y356DOPA-beta2 heterodimer of E. coli ribonucleotide reductase.
M. Seyedsayamdost (2007)
10.1073/PNAS.0409047102
Protein dynamics and electron transfer: electronic decoherence and non-Condon effects.
S. Skourtis (2005)
10.1021/JA074452O
Direct observation of a transient tyrosine radical competent for initiating turnover in a photochemical ribonucleotide reductase.
Steven Y. Reece (2007)
10.1021/JA047875O
Mimicking protein-protein electron transfer: voltammetry of Pseudomonas aeruginosa azurin and the Thermus thermophilus Cu(A) domain at omega-derivatized self-assembled-monolayer gold electrodes.
Kyoko Fujita (2004)
10.1063/1.452723
Electron tunneling through covalent and noncovalent pathways in proteins
D. Beratan (1987)
10.1002/ANIE.199311113
Electron Transfer Reactions in Chemistry: Theory and Experiment (Nobel Lecture)
R. Marcus (1993)
10.1021/JA043607E
Evidence against the hopping mechanism as an important electron transfer pathway for conformationally constrained oligopeptides.
F. Polo (2005)
10.1073/PNAS.71.9.3640
Electron transfer between biological molecules by thermally activated tunneling.
J. Hopfield (1974)
10.1073/PNAS.95.22.12759
Charge transfer and transport in DNA.
J. Jortner (1998)
10.1098/rstb.2006.1868
Darwin at the molecular scale: selection and variance in electron tunnelling proteins including cytochrome c oxidase
C. Moser (2006)
10.1002/CHIN.200727264
Distal Charge Transport in Peptides
E. Schlag (2007)
10.1021/JA076043Y
Site-specific insertion of 3-aminotyrosine into subunit alpha2 of E. coli ribonucleotide reductase: direct evidence for involvement of Y730 and Y731 in radical propagation.
M. Seyedsayamdost (2007)
10.1021/JA034872N
Long-range electron transfer over 4 nm governed by an inelastic hopping mechanism in self-assembled monolayers of helical peptides.
T. Morita (2003)
10.1021/JP072813G
Orientation-Dependent Kinetics of Heterogeneous Electron Transfer for Cytochrome c Immobilized on Gold: Electrochemical Determination and Theoretical Prediction
C. A. Bortolotti (2007)
10.1021/JA0401040
Long-range electron transfer across Peptide bridges: the transition from electron superexchange to hopping.
Rouba Abdel Malak (2004)
10.1016/J.TSF.2007.12.046
Photo-induced vectorial electron transfer through oriented metal-coordinated peptide assembly on a self-assembled monolayer
M. Higuchi (2008)
10.1002/PSC.974
Distance dependence of long‐range electron transfer through helical peptides
M. Kai (2008)



This paper is referenced by
10.1016/j.bioorg.2014.06.006
Mechanisms for control of biological electron transfer reactions.
Heather R Williamson (2014)
10.1109/CLEOE-IQEC.2013.6801020
Ultrafast electron dynamics in an amino acid measured by attosecond pulses
L. Belshaw (2013)
10.1073/pnas.1809913116
Reaction of O2 with a diiron protein generates a mixed-valent Fe2+/Fe3+ center and peroxide
J. Bradley (2019)
10.1016/j.abb.2013.10.004
MauG, a diheme enzyme that catalyzes tryptophan tryptophylquinone biosynthesis by remote catalysis.
Sooim Shin (2014)
10.1002/QUA.22530
Long‐range charge transfer in donor‐peptide bridge‐acceptor model systems—A theoretical study
N. Santhanamoorthi (2011)
10.1073/pnas.1000187107
Engineering of an alternative electron transfer path in photosystem II
Shirley Larom (2010)
10.1002/anie.201410618
Electron transfer in peptides: on the formation of silver nanoparticles.
S. Kracht (2015)
10.1021/la303770k
Linker-based control of electron propagation through ferrocene moieties covalently anchored onto insulator-based nanopores derived from a polystyrene-poly(methylmethacrylate) diblock copolymer.
F. Li (2012)
10.1016/j.actbio.2018.01.007
Microbial nanowires - Electron transport and the role of synthetic analogues.
Rhiannon G Creasey (2018)
10.1002/prot.24474
QM/MM study of the C—C coupling reaction mechanism of CYP121, an essential Cytochrome p450 of Mycobacterium tuberculosis
Victoria G. Dumas (2014)
10.1021/ja210656k
Dynamics of pyrophosphate ion release and its coupled trigger loop motion from closed to open state in RNA polymerase II.
Lin-Tai Da (2012)
10.1039/c8nr08878k
Thermoelectric properties of oligoglycine molecular wires.
Songjun Hou (2019)
10.1002/adma.201707083
Tailor-Made Functional Peptide Self-Assembling Nanostructures.
M. Amit (2018)
10.1186/s12953-016-0097-6
Investigation of proteome changes in osteoclastogenesis in low serum culture system using quantitative proteomics
Q. Xiong (2016)
Auto-assemblage de protéines pour la bioélectronique : étude du tranport de charges dans les fibres amyloïdes
Anaëlle Rongier (2018)
10.1088/0957-4484/22/21/215606
Design of single peptides for self-assembled conduction channels.
S. Y. Yew (2011)
10.1016/J.CPLETT.2016.08.004
Side chain effects in reactions of the potassium-tyrosine charge transfer complex
F. D. Silva (2016)
10.1016/j.freeradbiomed.2009.10.053
Dps proteins prevent Fenton-mediated oxidative damage by trapping hydroxyl radicals within the protein shell.
Giuliano Bellapadrona (2010)
10.1002/ANGE.201410618
Elektronentransfer in Peptiden: Bildung von Silbernanopartikeln†
S. Kracht (2015)
10.1039/C7RA06289C
Genetically encoded conductive protein nanofibers secreted by engineered cells
Ebuzer Kalyoncu (2017)
10.1038/s41598-020-69823-0
Polymerization mechanism of natural lacquer sap with special phase structure
J. Yang (2020)
10.1002/anie.201507271
Charge Tunneling along Short Oligoglycine Chains.
Mostafa Baghbanzadeh (2015)
10.1002/celc.202000088
Insights into the distance dependence of electron transfer through conformationally constrained peptides
Claudio Zuliani (2020)
10.1016/J.JELECHEM.2010.12.026
Dependence of nonadiabatic intramolecular dissociative electron transfers on stereochemistry and driving force
S. Antonello (2011)
10.1021/ACSCATAL.5B01854
Direct Electron Transfer from the FAD Cofactor of Cellobiose Dehydrogenase to Electrodes
C. Schulz (2016)
10.1002/9781119953678.RAD046
Electron Transfer in Peptides and Proteins
B. Giese (2012)
10.1021/acsami.6b16765
Peptide Cross-linkers: Immobilization of Platinum Nanoparticles Highly Dispersed on Graphene Oxide Nanosheets with Enhanced Photocatalytic Activities.
Tsukasa Mizutaru (2017)
10.1074/jbc.M113.545590
Structural and Molecular Basis of the Peroxynitrite-mediated Nitration and Inactivation of Trypanosoma cruzi Iron-Superoxide Dismutases (Fe-SODs) A and B
Alejandra Martínez (2014)
10.1039/c3cp50411e
Stepping stones in the electron transport from cells to electrodes in Geobacter sulfurreducens biofilms.
P. S. Bonanni (2013)
10.1016/j.jinorgbio.2018.05.008
A survey of methionine-aromatic interaction geometries in the oxidoreductase class of enzymes: What could Met-aromatic interactions be doing near metal sites?
D. S. Weber (2018)
Heme-dependent Tryptophan Oxidation: Mechanistic Studies on Tryptophan 2,3-Dioxygenase and MauG
Jiafeng Geng (2014)
10.1186/1742-4682-8-4
The self-organizing fractal theory as a universal discovery method: the phenomenon of life
A. Kurakin (2010)
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