← Back to Search
Acute Exposure To Boron In Nile Tilapia (Oreochromis Niloticus): Median-lethal Concentration (LC50), Blood Parameters, DNA Fragmentation Of Blood And Sperm Cells.
Ümit Acar, B. Inanan, F. Zemheri, O. S. Kesbiç, S. Yilmaz
Published 2018 · Chemistry, Medicine
Save to my Library
Download via 🐼 PaperPanda Download via oaDOI Download via OAB Download via LibKey Download via Google Google ScholarAnalyze on Scholarcy Visualize in Litmaps
Reduce the time it takes to create your bibliography by a factor of 10 by using the world’s favourite reference manager
Time to take this seriously.
Recently, Boron (B) contamination of aquatic ecosystem has received considerable critical attention due to its toxic effects at high concentrations on plants as well as animals. Previous studies on toxic effects of B have not dealt with DNA damages in blood and sperm cells of Nile tilapia (Oreochromis niloticus), together with blood parameters. This study consisted of two successive experiments purposes to determine these findings, including the median-lethal concentration (LC50) of B for Nile tilapia. In the first one, at 96 h, LC50 of B for Nile tilapia was 141.42 mg L-1 B. In the second one, Nile tilapia were treated with five elevated B concentrations (1, 5, 25, 50 and 100 mg L-1 B) and hematological, serum biochemical parameters, and DNA damages of Nile tilapia in these treatments were determined comparing with the control after 14 days of exposure. Hematological parameters (red blood cell count, hematocrit, and hemoglobin) were similar to each other in all groups while serum biochemical parameters (glucose, total protein, cholesterol, alkaline phosphatase, glutamic oxaloacetic transaminase, and glutamic pyruvic transaminase) in B treatments, especially in 50 and 100 mg L-1 B groups, were found significantly higher (P < 0.05). DNA fragmentation was detected in all blood cells in ≥25 mg L-1 B treatments, while all sperm cells in 100 mg L-1 B treatments. These results demonstrated the harmful effects of B at high concentration (50 and 100 mg L-1 B) on the DNA integrity of blood and sperm cells, and also the serum biochemical parameters.
This paper references
Toxicity to Gambusia affinis of certain pure chemicals in turbid waters
I. E. Wallen (1957)
Boron pollution in the Simav River, Turkey and various methods of boron removal
O. Okay (1985)
A simple technique for quantitation of low levels of DNA damage in individual cells.
N. Singh (1988)
A preliminary study on boron removal from Kizildere/Turkey geothermal waste water
O. Recepog̃lu (1991)
The Effect of Feeding Two Sources of Boron on Broiler Breeder Performance
A. Rossi (1993)
An integrated assessment of the biological effects of boron to the rainbow trout
J. A. Black (1993)
Testicular toxicity of boric acid (BA): relationship of dose to lesion development and recovery in the F344 rat.
W. Ku (1993)
The biochemical effects of physiologic amounts of dietary boron in animal nutrition models.
C. Hunt (1994)
Proposed physiologic functions of boron in plants pertinent to animal and human metabolism.
D. Blevins (1994)
An introduction to boron: history, sources, uses, and chemistry.
W. Woods (1994)
Comet assay in human biomonitoring studies: Reliability, validation, and applications
A. Collins (1997)
Boron is required for zebrafish embryogenesis
Effect of boron deprivation on reproductive parameters inXenopus laevis
D. Fort (1999)
Changes in liver enzyme activity in the teleost Sparus aurata in response to cadmium intoxication.
A. Vaglio (1999)
Toxicity of boron to rainbow trout: a weight-of-the-evidence assessment.
G. Loewengart (2001)
Acute exposure of Siberian sturgeon (Acipenser baeri, Brandt) yearlings to nitrite: median-lethal concentration (LC(50)) determination, haematological changes and nitrite accumulation in selected tissues.
M. Huertas (2002)
The efficacy of metomidate, clove oil, Aqui-S™ and Benzoak® as anaesthetics in Atlantic salmon (Salmo salar L.) smolts, and their potential stress-reducing capacity
Martin Iversen (2003)
The Physiological Effects of Dietary Boron
Tara A Devirian (2003)
Mutagenic effects of tributyltin and inorganic lead (Pb II) on the fish H. malabaricus as evaluated using the comet assay and the piscine micronucleus and chromosome aberration tests
M. Ferraro (2004)
Effects of cypermethrin and carbofuran on certain hematological parameters and prediction of their recovery in a freshwater teleost, Labeo rohita (Hamilton).
S. Adhikari (2004)
Boron in human and animal nutrition
F. Nielsen (2004)
Responses of cypermethrin‐induced stress in haematological parameters of Korean rockfish, Sebastes schlegeli (Hilgendorf)
Jung-Hoon Jee (2005)
Copper induced alterations of biochemical parameters in the gill and plasma of Oreochromis niloticus.
S. Monteiro (2005)
Application of Soil and Plant Analysis for Applied Research and Development in West Asia–North Africa: An International Center's Perspective
J. Ryan (2006)
Boron Functions in Plants and Animals: Recent Advances in Boron Research and Open Questions
H. Goldbach (2007)
The nutritional and metabolic effects of boron in humans and animals
S. Samman (2007)
Biochemical alteration induced by monocrotophos in the blood plasma of fish, Channa punctatus (Bloch)
S. Agrahari (2007)
The effect of praziquantel applied per os on selected haematological and biochemical indices in common carp (Cyprinus carpio L.)
E. Sudová (2008)
Acute toxicity of boron to juvenile white shrimp, Litopenaeus vannamei, at two salinities
E. Li (2008)
Is boron nutritionally relevant?
F. Nielsen (2008)
Effects of Fish Size and Water Temperature on the Acute Toxicity of Copper for Japanese Flounder, Paralichthys olivaceus, and Red Sea Bream, Pagrus major
T. Furuta (2008)
Fertilization capacity with rainbow trout DNA-damaged sperm and embryo developmental success.
S. Pérez-Cerezales (2010)
An overview of male reproductive studies of boron with an emphasis on studies of highly exposed Chinese workers.
Anthony R. Scialli (2010)
Reproductive toxicity parameters and biological monitoring in occupationally and environmentally boron-exposed persons in Bandırma, Turkey
Y. Duydu (2011)
Assessment of DNA integrity (COMET assay) in sperm cells of boron-exposed workers
Y. Duydu (2011)
Effects assessment: boron compounds in the aquatic environment.
Lucia Schoderboeck (2011)
A comparative study on the effects of a pesticide (cypermethrin) and two metals (copper, lead) to serum biochemistry of Nile tilapia, Oreochromis niloticus
Özgür Fırat (2011)
Effect of waterborne boron and molybdenum on survival, growth and feed intake of Indian major carp, Cirrhinus mrigala (Hamilton)
S. Adhikari (2012)
Boron as Testicular Toxicant in Mice (Mus domesticus)
E. Bustos-Obregón (2012)
Hematological and biochemical alterations in the fish Prochilodus lineatus caused by the herbicide clomazone.
L. Pereira (2013)
Biological effects of boron.
M. Kabu (2013)
Methods for boron removal from aqueous solutions — A review
J. Wolska (2013)
Constructed wetlands for boron removal: A review
Onur Can Türker (2014)
Deleterious effects of wastewater on the health status of fish: A field caging study
J. Cazenave (2014)
Serum and ultrastructure responses of common carp (Cyprinus carpio L.) during long-term exposure to zinc oxide nanoparticles.
J. Lee (2014)
Effects of silver nanoparticles (AgNPs) on hematological parameters of rainbow trout, Oncorhynchus mykiss
M. Imani (2014)
Effects of trophic exposure to diclofenac and dexamethasone on hematological parameters and immune response in freshwater fish.
J. Ribas (2016)
24-Epibrassinolide ameliorates the effects of boron toxicity on Arabidopsis thaliana (L.) Heynh by activating an antioxidant system and decreasing boron accumulation
Yonca Surgun (2016)
Responses of metabolic and antioxidant enzymatic activities in gill, liver and plasma of Catla catla during methyl parathion exposure
B. D. Abhijith (2016)
Differential expression analysis of boron transporters and some stress-related genes in response to 24-epibrassinolide and boron by semi-quantitative RT-PCR in Arabidopsis thaliana (L.) Heynh
Yonca Surgun (2016)
The Effects of Boric Acid on the Hepatosomatic and Viserosomatic Index Values of Rainbow Trout
M. Öz (2017)
Evaluation of DNA damage and physiological responses in Nile tilapia, Oreochromis niloticus (Linnaeus, 1758) exposed to sub-lethal diclofenac (DCF).
P. Pandey (2017)
Removal of boron from wastewater: Evaluation of seven poplar clones for B accumulation and tolerance.
Zhifan Chen (2017)
Antimicrobial agents, triclosan, chloroxylenol, methylisothiazolinone and borax, used in cleaning had genotoxic and histopathologic effects on rainbow trout.
E. Capkin (2017)
Effect of boric acid in rainbow trout (Oncorhynchus mykiss) growth performance
M. Öz (2018)
Effects of dimethoate alone and in combination with Bacilar fertilizer on oxidative stress in common carp, Cyprinus carpio.
Maryam Rezaei Shadegan (2018)
Transcriptomic analysis of boron hyperaccumulation mechanisms in Puccinellia distans.
Saniye Elvan Öztürk (2018)
DNA damage and oxidative stress induced by imidacloprid exposure in different tissues of the Neotropical fish Prochilodus lineatus.
C. E. Vieira (2018)
MOTILITY EVALUATION AND CRYOPRESERVATION OF FISH SPERM EXPOSED BY WATER-BORNE AND FOOD-BORNE BORON
B. Inanan (2018)
This paper is referenced by
Effects of boric acid on the growth performance and nutritional content of rainbow trout (Oncorhynchus mykiss)
M. Öz (2021)
Effects of acute ammonia exposure on antioxidant and detoxification metabolism in clam Cyclina sinensis.
Ge Hongxing (2021)
Progress of On-line Biological Monitoring Technology in Different Water Environment
Long Chen (2021)
Oxidative and DNA Damage Potential of Colemanite on Zebrafish: Brain, Liver and Blood
G. Alak (2020)
Elevated temperature affects growth and hemato‐biochemical parameters, inducing morphological abnormalities of erythrocytes in Nile tilapia Oreochromis niloticus
S. Islam (2020)
Identification of Growth Inhibitors of the Fish Pathogen Saprolegnia parasitica Using in silico Subtractive Proteomics, Computational Modeling, and Biochemical Validation
Sanjiv Kumar (2020)
The new aspects of using some safe feed additives on alleviated imidacloprid toxicity in farmed fish: a review
M. Naiel (2020)
Recent advances in adsorption and coagulation for boron removal from wastewater: A comprehensive review.
Jui-Yen Lin (2020)
Histopathology changes in the rainbow trout (Onchorhyncus mykiss) consuming boric acid supplemented fish fodder.
M. Öz (2020)
Acute toxicity and health effect of perfluoroisobutyronitrile on mice: a promising substitute gas-insulating medium to SF6
Xiaoxing Zhang (2020)
Effect of TRPV 4 Antagonist RN 1734 on DNA Damage and Cell Viability in MCF-7 and PC-3 Cell Lines
Murat Çakır (2019)
Propolis and Its Combination with Boric Acid Protect Against Ischemia/Reperfusion-Induced Acute Kidney Injury by Inhibiting Oxidative Stress, Inflammation, DNA Damage, and Apoptosis in Rats
F. Geyikoglu (2019)
Responses of Chlorella vulgaris exposed to boron: Mechanisms of toxicity assessed by multiple endpoints.
X. Chen (2019)
Characterizations of intracellular copper/zinc superoxide dismutase from yellow drum (Nibea albiflora, Richardson 1846) and its gene expressions under the ammonia/nitrite stress.
X. Wang (2019)