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Changes Of Thyroid Hormone Levels And Related Gene Expression In Zebrafish On Early Life Stage Exposure To Triadimefon.

Shao-ying Liu, Juhua Chang, Ying Zhao, Guonian Zhu
Published 2011 · Biology, Medicine

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In this study, zebrafish was exposed to triadimefon. Thyroid hormones levels and the expression of related genes in the hypothalamic-pituitary-thyroid (HPT) axis, including thyroid-stimulating hormone (TSH-beta), deiodinases (dio1 and dio2) and the thyroid hormone receptor (thraa and thrb) were evaluated. After triadimefon exposure, increased T4 can be explained by increased thyroid-stimulating hormone (TSH-beta). The conversion of T4 to T3 (deiodinase type I-dio1) was decreased, which reduced the T3 level. Thyroid hormone receptor beta (thrb) mRNA levels were significantly down-regulated, possibly as a response to the decreased T3 levels. The overall results indicated that triadimefon exposure could alter gene expression in the HPT axis and that mechanisms of disruption of thyroid status by triadimefon could occur at several steps in the synthesis, regulation, and action of thyroid hormones.
This paper references
10.1139/F84-004
Interrenal, thyroidal, and carbohydrate responses of rainbow trout (Salmo gairdneri) to environmental acidification
Scott B. Brown (1984)
10.1016/S0013-9351(86)80015-9
Effect of pesticide on circulating thyroid hormone levels in the freshwater catfish, Heteropneustes fossilis (Bloch).
A. K. Yadav (1986)
10.1016/0300-483X(91)90142-N
Effect of endosulfan on thyroid physiology in the freshwater catfish, Clarias batrachus.
N. Sinha (1991)
10.1002/AJA.1002030302
Stages of embryonic development of the zebrafish
C. Kimmel (1995)
10.1073/PNAS.94.24.13011
The role of thyroid hormone in zebrafish and axolotl development.
D. Brown (1997)
10.1080/026520399283678
Screening of selected pesticides for oestrogen receptor activation in vitro.
A. Vinggaard (1999)
10.1016/S0303-7207(99)00193-8
Temporal expression and T3 induction of thyroid hormone receptors α1 and β1 during early embryonic and larval development in zebrafish, Danio rerio
Yi-Wen Liu (2000)
10.1016/S0887-2333(00)00018-7
Screening of selected pesticides for inhibition of CYP19 aromatase activity in vitro.
A. Vinggaard (2000)
10.1016/S1532-0456(01)00271-X
Thyroid hormones in growth and development of fish.
D. Power (2001)
10.1046/J.1432-0436.2002.700104.X
Thyroid hormones are important for embryonic to larval transitory phase in zebrafish.
Y. Liu (2002)
10.1006/TAAP.2001.9347
Effects of currently used pesticides in assays for estrogenicity, androgenicity, and aromatase activity in vitro.
H. Andersen (2002)
10.1289/EHP.5785
Azole fungicides affect mammalian steroidogenesis by inhibiting sterol 14 alpha-demethylase and aromatase.
J. Zarn (2002)
10.1007/BF00043383
Measurement and regulation of thyroidal status in teleost fish
J. Eales (1993)
10.1089/THY.2005.15.799
Thyroid hormone deiodination in fish.
A. Orozco (2005)
10.1080/01926230601047808
Toxicity Profiles in Rats Treated with Tumorigenic and Nontumorigenic Triazole Conazole Fungicides: Propiconazole, Triadimefon, and Myclobutanil
D. Wolf (2006)
10.1016/J.ECOENV.2005.07.006
Comparative embryotoxicity and proteotoxicity of three carrier solvents to zebrafish (Danio rerio) embryos.
A. Hallare (2006)
10.1021/ES050972C
Effects of the antithyroid agent propylthiouracil in a partial life cycle assay with zebrafish.
L. V. D. van der Ven (2006)
10.1093/TOXSCI/KFM065
Toxicogenomic study of triazole fungicides and perfluoroalkyl acids in rat livers predicts toxicity and categorizes chemicals based on mechanisms of toxicity.
M. Martin (2007)
10.1016/J.MODGEP.2006.06.003
Gene expression in Xenopus laevis embryos after Triadimefon exposure.
E. Papis (2007)
10.1016/J.YGCEN.2007.02.020
The effect of 3,5,3'-triiodothyronine supplementation on zebrafish (Danio rerio) embryonic development and expression of iodothyronine deiodinases and thyroid hormone receptors.
C. Walpita (2007)
10.1016/j.taap.2007.10.030
Transcriptional responses in thyroid tissues from rats treated with a tumorigenic and a non-tumorigenic triazole conazole fungicide.
S. Hester (2008)
10.1016/j.mce.2008.06.008
Molecular biomarkers of endocrine disruption in small model fish
S. Scholz (2008)
10.1016/j.chemosphere.2009.07.074
Waterborne exposure to PFOS causes disruption of the hypothalamus-pituitary-thyroid axis in zebrafish larvae.
Xiongjie Shi (2009)
10.1210/en.2008-1795
Minireview: Thyrotropin-releasing hormone and the thyroid hormone feedback mechanism.
M. Chiamolera (2009)
10.1016/j.aquatox.2009.01.006
Changes of thyroid hormone levels and related gene expression in Chinese rare minnow (Gobiocypris rarus) during 3-amino-1,2,4-triazole exposure and recovery.
W. Li (2009)
10.1021/ES9012454
Simple, rapid zebrafish larva bioassay for assessing the potential of chemical pollutants and drugs to disrupt thyroid gland function.
D. Raldúa (2009)
10.1897/08-339.1
Chronic toxicity of five structurally diverse demethylase-inhibiting fungicides to the crustacean Daphnia magna: a comparative assessment.
Enken Hassold (2009)
10.1016/j.aquatox.2009.10.022
Exposure to DE-71 alters thyroid hormone levels and gene transcription in the hypothalamic-pituitary-thyroid axis of zebrafish larvae.
Liqin Yu (2010)
10.1016/j.bcp.2009.11.006
Endocrine disruptors and thyroid hormone physiology.
M. Jugan (2010)



This paper is referenced by
10.1016/j.ecoenv.2021.112417
Xenopus laevis tadpoles exposed to metamifop: Changes in growth, behavioral endpoints, neurotransmitters, antioxidant system and thyroid development.
Rui Liu (2021)
10.1016/J.JHAZMAT.2021.126142
Physiological and transcriptomic changes of zebrafish (Danio rerio) embryos-larvae in response to 2-MIB exposure.
Weicheng Zhou (2021)
10.1016/j.scitotenv.2021.145963
The possible hormetic effects of fluorene-9-bisphenol on regulating hypothalamic-pituitary-thyroid axis in zebrafish.
Meng Jin (2021)
10.1039/d0en00952k
Interactive transgenerational effects of polystyrene nanoplastics and ethylhexyl salicylate on zebrafish
Ranran Zhou (2021)
10.1080/15569543.2021.1895841
Effects of pesticide NeemAzal-T/S on thyroid, stress hormone and some cytokines levels in freshwater common carp, Cyprinus carpio L
Nuh Korkmaz (2021)
10.1111/jai.13998
Evaluating the toxic potential of agrochemicals on the hypothalamic‐pituitary‐thyroid axis in tilapia (Oreochromis mossambicus)
Parth Pandya (2020)
10.1016/j.reprotox.2020.06.002
Distinguishing mode of action of compounds inducing craniofacial malformations in zebrafish embryos to support dose-response modeling in combined exposures.
Harm J Heusinkveld (2020)
10.1016/j.scitotenv.2020.141860
Tralopyril induces developmental toxicity in zebrafish embryo (Danio rerio) by disrupting the thyroid system and metabolism.
X. Chen (2020)
10.1016/j.fct.2020.111117
Dose addition in chemical mixtures inducing craniofacial malformations in zebrafish (Danio rerio) embryos.
Maria Zoupa (2020)
10.1007/s10646-020-02161-z
Effects of perfluorooctanoic acid (PFOA) on the thyroid status, vitellogenin, and oxidant–antioxidant balance in the Murray River rainbowfish
A. Miranda (2020)
10.1016/j.neuro.2019.05.008
Changes in thyroid hormone activity disrupt photomotor behavior of larval zebrafish.
Kyla M Walter (2019)
10.1080/09291016.2019.1566987
Effect of seasonal water temperature variation on the blood serums thyroid hormone levels of juvenile chub fishes (Squalius cappadocicus)
S. C. Özeren (2020)
10.1016/j.cbpc.2019.108578
Exposure to nitrite alters thyroid hormone levels and morphology in Takifugu rubripes.
X. Gao (2019)
10.1016/j.scitotenv.2019.04.177
Thyroid endocrine disruption effects of perfluoroalkyl phosphinic acids on zebrafish at early development.
Menglin Liu (2019)
10.1016/j.fsi.2019.05.018
The PFOS disturbed immunomodulatory functions via nuclear Factor-κB signaling in liver of zebrafish (Danio rerio).
J. Guo (2019)
10.1016/j.chemosphere.2019.124802
Lethal toxicity and gene expression changes in embryonic zebrafish upon exposure to individual and mixture of malathion, chlorpyrifos and lambda-cyhalothrin.
Weifeng Shen (2019)
10.1016/j.chemosphere.2019.125288
Effect of triadimefon and its metabolite on adult amphibians Xenopus laevis.
Wenjun Zhang (2019)
10.1016/j.ygcen.2018.11.007
Effects of thyroid hormone disruption on the ontogenetic expression of thyroid hormone signaling genes in developing zebrafish (Danio rerio).
Kyla M Walter (2019)
10.1016/j.aquatox.2019.04.002
Parental exposure to tebuconazole causes thyroid endocrine disruption in zebrafish and developmental toxicity in offspring.
Shuying Li (2019)
10.1002/em.22147
Effects of fluoride on morphology, growth, development, and thyroid hormone of Chinese toad (Bufo gargarizans) embryos
Y. Zhang (2018)
10.1016/j.chemosphere.2018.06.152
Changes in thyroid status of Menidia beryllina exposed to the antifouling booster irgarol: Impacts of temperature and salinity.
L. B. Moreira (2018)
10.1016/j.toxrep.2018.02.018
Effects of the environmental endocrine disrupting compound benzo[a]pyrene on thyroidal status of abu mullet (Liza abu) during short-term exposure
A. Movahedinia (2018)
10.1021/acs.est.7b04970
Impacts of Salinity and Temperature on the Thyroidogenic Effects of the Biocide Diuron in Menidia beryllina.
L. B. Moreira (2018)
10.1002/bmc.4185
Simultaneous quantification of T4, T3, rT3, 3,5-T2 and 3,3'-T2 in larval zebrafish (Danio rerio) as a model to study exposure to polychlorinated biphenyls.
X. Chen (2018)
10.1177/0748233717748099
Short-term induction of vitellogenesis in the immature male yellowfin seabream (Acanthopagrus latus) exposed to bisphenol A and 17β-estradiol
Ahmad Negintaji (2018)
10.1016/j.scitotenv.2018.06.213
Developmental toxicity of synthetic phenolic antioxidants to the early life stage of zebrafish.
Xiaoxi Yang (2018)
10.1016/j.ecoenv.2017.02.043
Semicarbazide-induced thyroid disruption in Japanese flounder (Paralichthys olivaceus) and its potential mechanisms.
Zonghao Yue (2017)
10.1016/j.chemosphere.2017.07.119
Acute nitrite exposure alters the metabolism of thyroid hormones in grass carp (Ctenopharyngodon idellus).
C. Xiao (2017)
10.1016/j.envpol.2017.05.072
The cardiovascular toxicity of triadimefon in early life stage of zebrafish and potential implications to human health.
Hong-Cui Liu (2017)
10.1002/tox.22227
The regulation of transcriptome responses in zebrafish embryo exposure to triadimefon
L. Hsu (2017)
10.3390/ijms18040817
Zebrafish as an Alternative Vertebrate Model for Investigating Developmental Toxicity—The Triadimefon Example
Maria Zoupa (2017)
10.1016/j.chemosphere.2016.09.075
Joint acute and endocrine disruptive toxicities of malathion, cypermethrin and prochloraz to embryo-larval zebrafish, Danio rerio.
Dongmei Guo (2017)
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