Synthesis And Transdermal Penetration Of NSAID Glycoside Esters.
H. Swart, J. Breytenbach, J. Hadgraft, J. du Plessis
Published 2005 · Chemistry, Medicine
Download PDFAnalyze on Scholarcy
The glucoside and mannoside derivatives of the NSAIDs flurbiprofen, ibuprofen, ketoprofen and naproxen were synthesised and their penetration through human skin was determined. Experimental transdermal flux data showed that the parent NSAIDs penetrated human skin to a much higher extent than the glycosides.
This paper is referenced by
SYNTHESIS AND FORMULATION OF IBUPROFEN PRO-DRUGS FOR ENHANCED TRANSDERMAL ABSORPTION
Murad N Abualhasan (2014)
Topical delivery of clofazimine from an avocado oil nano-emulsion
Hélène Joubert (2016)
Case by Case Physicochemical and In Vitro/ In Vivo Biopharmaceutical Characterization of Alkyl Polyglucoside-Based Vehicles: Ketoprofen as a Model Drug
Ivana Jakšić (2010)
Influence of selected formulation factors on the transdermal delivery of ibuprofen
Aysha Bibi Moosa (2012)
Effect of counter-ions and penetration enhancers on the skin permeation of flurbiprofen.
Xu Ma (2010)
Transdermal permeation of novel n-acetyl-glucosamine/NSAIDs mutual prodrugs
Bridg'ette Israel (2012)
A Novel Murine Model for the In Vivo Study of Transdermal Drug Penetration
G. Erős (2012)
Lipophilicity study of some non-steroidal anti-inflammatory agents and cephalosporin antibiotics: a review.
Monika Dabrowska (2011)
Synthesis of methoxypoly(ethylene glycol) carbonate prodrugs of zidovudine and penetration through human skin in vitro.
D. N’Da (2009)
UNIVERSIDADE ESTADUAL DA PARAÍBA CENTRO DE CIÊNCIAS BIOLÓGICAS E DA SAÚDE DEPARTAMENTO DE FARMÁCIA CURSO DE FARMÁCIA
Jéssica Carol de Jesus (2010)
Administração cutânea de fármacos: desafios e estratégias para o desenvolvimento de formulações transdérmicas
José Alexsandro da Silva (2010)
Preparation of Cellulose Acetate Fibers Loaded with Naproxen Ester Prodrug through Wet-Spinning
Xiao Min Wu (2010)
Study of Ibuprofen Glucopyranoside Derivative Synthesis by Candida antarctica Lipase in Organic Solvent
Xiangguo Zhao (2007)
Lipid nanoparticles for prolonged topical delivery: an in vitro and in vivo investigation.
Carmelo Puglia (2008)
In vitro skin models as a tool in the optimization of drug formulation
Zinaida Shakel (2017)
An equation for the prediction of human skin permeability of neutral molecules, ions and ionic species.
Keda Zhang (2017)
Effect of low molecular weight chitosans on drug permeation through mouse skin: 1. Transdermal delivery of baicalin.
X. Zhou (2010)
Two-step enzymatic selective synthesis of water-soluble ketoprofen-saccharide conjugates in organic media.
H. Wang (2009)
Animal models for percutaneous absorption.
E. Jung (2015)
Tuning the rheological properties of an ammonium methacrylate copolymer for the design of adhesives suitable for transdermal patches
Gaia M G Quaroni (2018)
Topical delivery of clofazimine, artemisone and decoquinate utilizing vesicles as carrier system
Lindi van Zyl (2018)
In Vitro and in Vivo Evaluation of Transdermal Absorption of Naproxen Sodium
Dalia A. Attia (2009)
Ester prodrug-loaded electrospun cellulose acetate fiber mats as transdermal drug delivery systems
Xiao-mei Wu (2010)
Formulation and evaluation of different transdermal delivery systems with flurbiprofen as marker
Lindi van Zyl (2012)
Determination of nonsteroidal anti-inflammatory drugs in human plasma by LC-MS-MS with a hydrophilic polymer column
Xiao-Pen Lee (2010)
Optimization of ibuprofen gel formulations using experimental design technique for enhanced transdermal penetration.
Yun-Seok Rhee (2008)
Avaliação do potencial de carreadores lipídicos nanoestruturados para a administração cutânea de trans-resveratrol
Naiara Fachinetti (2013)
Programa de Pós-graduação em Ciências Farmacêuticas Área de Pesquisa e Desenvolvimento de Fármacos e Medicamentos
Câmpus de Araraquara (2013)
Transdermal drug delivery: progress and challenges
K. Ita (2014)
Synthesis and evaluation of novel prodrugs of naproxen
Prabodh Chander Sharma (2010)
Preparation of naproxen–ethyl cellulose microparticles by spray-drying technique and their application to textile materials
Mesut Arıcı (2014)
Prodrugs for transdermal drug delivery – trends and challenges
K. Ita (2016)See more