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Prediction Of Strength And Strain Of The Proximal Femur By A CT-based Finite Element Method.

M. Bessho, I. Ohnishi, J. Matsuyama, T. Matsumoto, K. Imai, K. Nakamura
Published 2007 · Engineering, Medicine

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Hip fractures are the most serious complication of osteoporosis and have been recognized as a major public health problem. In elderly persons, hip fractures occur as a result of increased fragility of the proximal femur due to osteoporosis. It is essential to precisely quantify the strength of the proximal femur in order to estimate the fracture risk and plan preventive interventions. CT-based finite element analysis could possibly achieve precise assessment of the strength of the proximal femur. The purpose of this study was to create a simulation model that could accurately predict the strength and surface strains of the proximal femur using a CT-based finite element method and to verify the accuracy of our model by load testing using fresh frozen cadaver specimens. Eleven right femora were collected. The axial CT scans of the proximal femora were obtained with a calibration phantom, from which the 3D finite element models were constructed. Materially nonlinear finite element analyses were performed. The yield and fracture loads were calculated, while the sites where elements failed and the distributions of the principal strains were determined. The strain gauges were attached to the proximal femoral surfaces. A quasi-static compression test of each femur was conducted. The yield loads, fracture loads and principal strains of the prediction significantly correlated with those measured (r=0.941, 0.979, 0.963). Finite element analysis showed that the solid elements and shell elements in undergoing compressive failure were at the same subcapital region as the experimental fracture site.
This paper references
10.1115/1.2895412
Fracture prediction for the proximal femur using finite element models: Part I--Linear analysis.
J. C. Lotz (1991)
10.1016/S1350-4533(01)00045-5
Improved prediction of proximal femoral fracture load using nonlinear finite element models.
J. Keyak (2001)
10.1016/S0021-9290(98)00118-3
Finite element analysis of trabecular bone structure: a comparison of image-based meshing techniques.
D. Ulrich (1998)
10.1016/S1350-4533(03)00081-X
Comparison of in situ and in vitro CT scan-based finite element model predictions of proximal femoral fracture load.
J. Keyak (2003)
10.2106/00004623-199308000-00009
Age-related changes in the tensile properties of cortical bone. The relative importance of changes in porosity, mineralization, and microstructure.
R. Mccalden (1993)
10.1016/0141-5425(92)90100-Y
Three-dimensional finite element modelling of bone: effects of element size.
J. Keyak (1992)
10.1016/S1350-4533(01)00094-7
Prediction of fracture location in the proximal femur using finite element models.
J. Keyak (2001)
10.1016/0021-9290(94)90056-6
Predicting the compressive mechanical behavior of bone.
T. Keller (1994)
10.1016/0021-9290(94)90054-X
Differences between the tensile and compressive strengths of bovine tibial trabecular bone depend on modulus.
T. M. Keaveny (1994)
10.1007/s002239900308
Spinal Trabecular Bone Loss and Fracture in American and Japanese Women
M. Ito (1997)
10.1016/S1350-4533(98)00054-X
Comparison of geometry-based and CT voxel-based finite element modelling and experimental validation.
M. Lengsfeld (1998)
10.1016/S1350-4533(03)00030-4
Relationships between material properties and CT scan data of cortical bone with and without metastatic lesions.
T. S. Kaneko (2003)
10.1016/S8756-3282(97)00072-0
Volumetric quantitative computed tomography of the proximal femur: precision and relation to bone strength.
T. Lang (1997)
10.1016/0021-9290(75)90075-5
The elastic and ultimate properties of compact bone tissue.
D. Reilly (1975)
10.1007/s007740050072
Fracture simulation of the femoral bone using the finite-element method: How a fracture initiates and proceeds
T. Ota (1999)
10.1302/0301-620X.43B4.647
LOW-ANGLE FIXATION IN FRACTURES OF THE FEMORAL NECK
R. Garden (1961)
10.1016/S0021-9290(97)00123-1
Prediction of femoral fracture load using automated finite element modeling.
J. Keyak (1997)
10.1016/S0021-9290(03)00257-4
Comparison of the elastic and yield properties of human femoral trabecular and cortical bone tissue.
Harun H. Bayraktar (2004)
10.1016/S0020-1383(99)00120-5
Strain gauges used in the mechanical testing of bones. Part I: Theoretical and technical aspects.
J. Cordey (1999)
10.1115/1.2794181
Development and validation of a three-dimensional finite element model of the pelvic bone.
M. Dalstra (1995)
10.1016/S0021-9290(99)00099-8
Femoral strength is better predicted by finite element models than QCT and DXA.
D. Cody (1999)
10.1097/01.blo.0000164400.37905.22
Predicting Proximal Femoral Strength Using Structural Engineering Models
J. Keyak (2005)
10.1090/qam/48291
Soil mechanics and plastic analysis or limit design
D. C. Drucker (1952)
10.1016/0021-9290(91)90006-9
Tensile and compressive properties of cancellous bone.
L. Røhl (1991)
10.1016/0141-5425(93)90066-8
Validation of an automated method of three-dimensional finite element modelling of bone.
J. Keyak (1993)
10.1016/0141-1187(81)90117-6
Finite elements in plasticity : theory and practice
D. Owen (1980)
10.14359/7388
Behavior of Concrete under Biaxial Stresses
H. Kupfer (1969)
Reliable Isotropic Tetrahedral Mesh Generation Based on an Advancing Front Method
Y. Ito (2004)
10.1097/00005131-200209000-00005
Magnetic Resonance Imaging of the Knee After Ipsilateral Femur Fracture
Kyle F. Dickson (2002)
10.1136/bmj.296.6631.1238
Statistics in Medicine: Calculating confidence intervals for regression and correlation
D. Altman (1988)
10.1097/01.blo.0000174736.50964.3b
Predicting the Strength of Femoral Shafts with and without Metastatic Lesions
J. Keyak (2005)
10.1002/JBMR.5650081008
Simple measurement of femoral geometry predicts hip fracture: The study of osteoporotic fractures
K. Faulkner (1993)
10.1007/978-3-540-39899-8_36
Intensity-Based 2D-3D Spine Image Registration Incorporating One Fiducial Marker
Daniel B. Russakoff (2003)



This paper is referenced by
10.1142/S0219519411004010
MICRO-FINITE ELEMENT ANALYSIS OF TRABECULAR BONE YIELD BEHAVIOR — EFFECTS OF TISSUE NONLINEAR MATERIAL PROPERTIES
He Gong (2011)
10.1016/j.medengphy.2015.05.011
Individual and combined effects of OA-related subchondral bone alterations on proximal tibial surface stiffness: a parametric finite element modeling study.
Morteza Amini (2015)
10.1063/1.4938990
Modeling of the mechanical behavior of the human femur: Stress analysis and strain
Dalila Belaid (2015)
10.1016/j.jbiomech.2014.09.016
Quantitative computed tomography-based finite element analysis predictions of femoral strength and stiffness depend on computed tomography settings.
D. Dragomir-Daescu (2015)
Análise Estrutural via MEF de um Fêmur Reconstruído a partir de Imagens de Tomografia com Mapeamento de Densidades
M. T. Bahia (2016)
10.1007/s10856-011-4469-2
Biomechanical evaluation of porous bioactive ceramics after implantation: micro CT-based three-dimensional finite element analysis
L. Ren (2011)
10.1016/j.jbiomech.2008.10.039
Validation of subject-specific automated p-FE analysis of the proximal femur.
N. Trabelsi (2009)
10.1007/s10439-010-0196-y
Robust QCT/FEA Models of Proximal Femur Stiffness and Fracture Load During a Sideways Fall on the Hip
D. Dragomir-Daescu (2010)
10.1007/978-1-4614-4328-5_6
Development of Bioabsorbable Interference Screws: How Biomaterials Composition and Clinical and Retrieval Studies Influence the Innovative Screw Design and Manufacturing Processes
Iulian Vasile Antoniac (2013)
10.1016/j.jbiomech.2013.11.004
A novel methodology for generating 3D finite element models of the hip from 2D radiographs.
Jérôme Thevenot (2014)
10.17530/JEF.14.02.1.1
Finite Element Modeling as Three Dimensional of Effect of Cutting Speed in Turning Process
Kadir Gok (2014)
Estimation of bone strength from pediatric radiographs of the forearm.
B. Varghese (2008)
10.1016/j.injury.2017.09.023
Location of atypical femoral fracture can be determined by tensile stress distribution influenced by femoral bowing and neck-shaft angle: a CT-based nonlinear finite element analysis model for the assessment of femoral shaft loading stress.
Yoto Oh (2017)
10.4028/www.scientific.net/AMM.775.415
A Preliminary Study of DXA and QCT Derived Femur Cross-Section Stiffness
Yunhua Luo (2015)
10.1016/j.jmbbm.2019.103593
Comparing the fracture limits of the proximal femur under impact and quasi-static conditions in simulation of a sideways fall.
Fatemeh Jazinizadeh (2020)
10.1016/j.jtbi.2008.08.017
Requirements for comparing the performance of finite element models of biological structures.
E. Dumont (2009)
10.1098/rsta.2010.0046
Mechanical testing of bones: the positive synergy of finite–element models and in vitro experiments
L. Cristofolini (2010)
10.1007/8415_2011_86
Patient Specific Modeling of Musculoskeletal Fractures
Eran Peleg (2011)
10.1177/1056789514537919
Multiscale finite element modelling of ductile damage behaviour of the human femur under dynamic loading
Hakim Naceur (2015)
GELİŞİMSEL KALÇA DİSPLAZİLİ KEMİĞİN SONLU ELEMANLAR ANALiZi VE NORMAL KEMİKLE KARŞILAŞTIRILMASI
Burcu Tanriverdi (2017)
10.7862/RM.2016.8
Formation of microcracks near surgical defect in femur: Assessment of ultimate loading conditions
Sergei Bosiakov (2016)
10.1016/j.jbiomech.2018.08.003
Linear and nonlinear analyses of femoral fractures: Computational/experimental study.
Majid Mirzaei (2018)
10.1016/J.JBIOMECH.2007.06.017
Reliable simulations of the human proximal femur by high-order finite element analysis validated by experimental observations.
Z. Yosibash (2007)
10.3109/17453674.2012.678804
Experimental evaluation of new concepts in hip arthroplasty
T. Wik (2012)
' s personal copy Patient specific quantitative analysis of fracture fixation in the proximal femur implementing principal strain ratios . Method and experimental validation
E. Peleg (2010)
10.1016/j.jbiomech.2012.02.006
Prediction of the mechanical response of the femur with uncertain elastic properties.
Hagen Wille (2012)
10.1177/0954411913508054
Dental application of novel finite element analysis software for three-dimensional finite element modeling of a dentulous mandible from its computed tomography images
Keiko Nakamura (2013)
10.1299/JBSE.13-00163
Nonlinear mechanical analysis of posterior spinal instrumentation for osteoporotic vertebra: Effects of mechanical properties of the rod on the failure risks around the screw
Daisuke Tawara (2014)
10.1016/B978-0-12-810493-4.00018-3
Statistical Shape and Appearance Models for Bone Quality Assessment
Patrik Raudaschl (2017)
10.1016/J.JMBBM.2017.05.028
Extensiometric analysis of strain in craniofacial bones during implant-supported palatal expansion.
C. Elias (2017)
10.1016/j.medengphy.2018.02.008
Femoral fracture load and fracture pattern is accurately predicted using a gradient-enhanced quasi-brittle finite element model.
Ifaz T Haider (2018)
10.1016/j.medengphy.2016.08.010
Morphology based anisotropic finite element models of the proximal femur validated with experimental data.
W. Enns-Bray (2016)
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