Please confirm you are human (Sign Up for free to never see this)
← Back to Search
Reduction Of Protein Adsorption To A Solid Surface By A Coating Composed Of Polymeric Micelles With A Glass-like Core.
B. Hofs, A. Brzozowska, A. de Keizer, W. Norde, M. C. Cohen Stuart
Published 2008 · Chemistry, Medicine
Save to my Library
Download PDFAnalyze on Scholarcy
Adsorption studies by optical reflectometry show that complex coacervate core micelles (C3Ms) composed of poly([4-(2-amino-ethylthio)-butylene] hydrochloride)(49)-block-poly(ethylene oxide)(212) and poly([4-(2-carboxy-ethylthio)-butylene] sodium salt)(47)-block-poly(ethylene oxide)(212) adsorb in equal amounts to both silica and cross-linked 1,2-polybutadiene (PB). The C3Ms have an almost glass-like core and atomic force microscopy of a dried layer of adsorbed C3Ms shows densely packed flattened spheres on silica, which very probably are adsorbed C3Ms. Experiments were performed with different types of surfaces, solvents, and proteins; bare silica and cross-linked 1,2-PB, NaNO(3) and phosphate buffer, and lysozyme, bovine serum albumin, beta-lactoglobulin, and fibrinogen. On the hydrophilic surface the coating reduces protein adsorption >90% in 0.1 M phosphate buffer, whereas the reduction on the coated hydrophobic surface is much lower. Reduction is better in phosphate buffer than in NaNO(3), except for the positively charged lysozyme, where the effect is reversed.
This paper references
Effects of ionic strength and surface charge on protein adsorption at PEGylated surfaces.
S. Pasche (2005)
Protein spreading kinetics at liquid-solid interfaces via an adsorption probe method.
M. Santore (2005)
Weak Polyacid Brushes: Preparation by LB Deposition and Optically Detected Titrations
E. Currie (1999)
Irreversible structural transitions in mixed micelles of oppositely charged diblock copolymers in aqueous solution
I. Voets (2007)
Basics of macroscopic properties of adsorbed protein layers formed at air-water interfaces based on molecular parameters
P. A. Wierenga (2005)
Structure and Mechanical Response of Self-Assembled Poly(butadiene)-b-poly(ethylene oxide) Colloids Probed by Atomic Force Microscopy
Shuliang Li (2005)
Structures and functionalities of milk proteins.
D. Wong (1996)
Protein—surface interactions in the presence of polyethylene oxide: II. Effect of protein size
Seok Hee Jeon (1991)
Internal structure of a thin film of mixed polymeric micelles on a solid/liquid interface.
I. Voets (2008)
Poly(l-lysine)-graft-poly(ethylene glycol) Assembled Monolayers on Niobium Oxide Surfaces: A Quantitative Study of the Influence of Polymer Interfacial Architecture on Resistance to Protein Adsorption by ToF-SIMS and in Situ OWLS
S. Pasche (2003)
Biomaterials: where we have been and where we are going.
B. Ratner (2004)
Protein adsorption on surfaces with grafted polymers: a theoretical approach.
I. Szleifer (1997)
Tethered polymer chains: surface chemistry and their impact on colloidal and surface properties.
E. Currie (2003)
Adsorption of the Phosphate Groups on Silica Hydroxyls: An ab Initio Study
V. Murashov (1999)
Electrokinetic Studies on Fibrinogen. V. The Determination of the Isoelectric Point by the Streaming Potential Method
T. Abe (1955)
In Situ Atomic Force Microscopy Imaging of Adsorbed Block Copolymer Micelles
I. W. Hamley (2004)
Electrostatic interactions in protein adsorption probed by comparing lysozyme and succinylated lysozyme.
M. van der Veen (2004)
Complex coacervation core micelles as anti-fouling agents on silica and polystyrene surfaces
S. V. D. Burgh (2004)
Methods for reducing biosensor membrane biofouling.
Adsorption of proteins from solution at the solid-liquid interface.
W. Norde (1986)
Adsorption of Graft Copolymers onto Silica and Titania
H. D. Bijsterbosch (1998)
Adsorption and displacement of a globular protein on hydrophilic and hydrophobic surfaces
R. J. Marsh (2002)
Formation of Adsorbed Protein Layers.
The specific refractive increment of some purified proteins.
G. E. Perlmann (1948)
Poly(ethylene oxide) Grafted to Silicon Surfaces: Grafting Density and Protein Adsorption.
Surface exclusion effects in adsorption processes
P. Schaaf (1989)
A model for fibrinogen: domains and sequence.
J. Weisel (1985)
Protein—surface interactions in the presence of polyethylene oxide
S. Jeon (1991)
Surface micelles formation by adsorption of block copolymers
C. Ligoure (1991)
Effect of chain density on inhibition of protein adsorption by poly(ethylene glycol) based coatings
Martin Malmsten (1998)
Grafted poly(ethylene oxide) brushes as nonfouling surface coatings.
D. Leckband (1999)
Water-soluble synthetic polymers: properties and behavior
P. Molyneux (1983)
Protein interactions at solid surfaces
P. Claesson (1995)
Assembly of polyelectrolyte-containing block copolymers in aqueous media
M. C. Stuart (2005)
Kinetics of polymer adsorption in stagnation point flow
J. Dijt (1990)
Structure of serum albumin.
D. Carter (1994)
Polymer surface with graft chains
K. Kato (2003)
Kinetics of block copolymer adsorption on dielectric surfaces from a selective solvent
M. R. Munch (1990)
Self-assembled monolayers and polymer brushes in biotechnology: current applications and future perspectives.
W. Senaratne (2005)
Structure of adsorbed and desorbed proteins
W. Norde (1992)
Why surfaces modified by flexible polymers often have a finite contact angle for good solvents.
M. C. Cohen Stuart (2006)
Relationship between interfacial forces measured by colloid-probe atomic force microscopy and protein resistance of poly(ethylene glycol)-grafted poly(L-lysine) adlayers on niobia surfaces.
S. Pasche (2005)
Toward a toolbox of functional block copolymers via free-radical addition of mercaptans
J. Justynska (2005)
This paper is referenced by
Surface functionalization of zirconium dioxide nano-adsorbents with 3-aminopropyl triethoxysilane and promoted adsorption activity for bovine serum albumin
Gen Liu (2016)
Polymer brushes through adsorption: From early attempts to the ultra-dense and reversible ‘zipper brush
Wiebe M. de Vos (2012)
Sol–gel synthesis of mesoporous silicas containing albumin and guanidine polymers and its application to the bilirubin adsorption
A. Timin (2013)
Features of adsorption of globular proteins by nanoporous silica
N. A. El’tekova (2010)
On Complex Coacervate Core Micelles: Structure-Function Perspectives
J. R. Magana (2020)
Extension of the broadband single-mode integrated optical waveguide technique to the ultraviolet spectral region and its applications.
R. S. Wiederkehr (2014)
Choline Derivate-Modified Doxorubicin Loaded Micelle for Glioma Therapy.
J. Li (2015)
Reduction of protein adsorption on silica and polysulfone surfaces coated with complex coacervate core micelles with poly(vinyl alcohol) as a neutral brush forming block
A. M. Brzozowska (2010)
Reduction of protein adsorption on surfaces coated with Complex Coacercate Core Micelles
A. M. Brzozowska (2010)
Urease adsorption and activity on magnetite nanoparticles functionalized with monofunctional and bifunctional surface layers
R. P. Pogorilyi (2013)
Formation and structure of ionomer complexes from grafted polyelectrolytes
A. M. Brzozowska (2011)
Electrostatically Driven Assembly of Polyelectrolytes
I. Voets (2016)
Grafted block complex coacervate core micelles and their effect on protein adsorption on silica and polystyrene
A. M. Brzozowska (2010)
On the stability of the polymer brushes formed by adsorption of ionomer complexes on hydrophilic and hydrophobic surfaces.
A.M. Brzozowska (2011)
Adsorption kinetics and stability of poly(ethylene oxide)-block-polystyrene micelles on polystyrene surface
Bo Peng (2013)
A brief review of environmentally benign antifouling and foul-release coatings for marine applications
P. Buskens (2012)
Rapid Hepatobiliary Excretion of Micelle-Encapsulated/Radiolabeled Upconverting Nanoparticles as an Integrated Form
H. J. Seo (2015)
Interaction of albumin with silica and carbon adsorbent surfaces
N. A. El’tekova (2013)
Polyelectrolyte complexes: bulk phases and colloidal systems.
J. van der Gucht (2011)
Grafted ionomer complexes and their effect on protein adsorption on silica and polysulfone surfaces
A. M. Brzozowska (2010)
Reduction of protein adsorption on silica and polystyrene surfaces due to coating with Complex Coacervate Core Micelles
A. M. Brzozowska (2009)
Investigating Protein Adsorption via Spectroscopic Ellipsometry
M. F. Mora (2009)
Co-assembly Towards Janus Micelles
I. Voets (2010)
Corrosion behavior of DLC-coated NiTi alloy in the presence of serum proteins
R. Hang (2010)
Complex Coacervate Core Micelles Containing Poly(vinyl alcohol) Inhibit Ice Recrystallization.
Christian C. M. Sproncken (2018)