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Smart Chemistry-based Nanosized Drug Delivery Systems For Systemic Applications: A Comprehensive Review.

T. Ramasamy, H. B. Ruttala, B. Gupta, B. K. Poudel, H. Choi, C. Yong, J. Kim
Published 2017 · Medicine

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This review focuses on the smart chemistry that has been utilized in developing polymer-based drug delivery systems over the past 10years. We provide a comprehensive overview of the different functional moieties and reducible linkages exploited in these systems, and outline their design, synthesis, and application from a therapeutic efficacy viewpoint. Furthermore, we highlight the next generation nanomedicine strategies based on this novel chemistry.
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