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Type 2 Diabetes Mellitus And Risk Of Stress, Urge And Mixed Urinary Incontinence.

K. Danforth, M. Townsend, G. Curhan, N. Resnick, F. Grodstein
Published 2009 · Medicine

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PURPOSE To improve the understanding of the etiological relation between type 2 diabetes and urinary incontinence, we examined associations between diabetes and urinary incontinence type in 71,650 women 37 to 79 years old in the Nurses' Health Study and the Nurses' Health Study II. MATERIALS AND METHODS From 1976 to 2000 in the Nurses' Health Study and 1989 to 2001 in the Nurses' Health Study II participants reported diagnoses of type 2 diabetes. Women with incident urinary incontinence at least weekly were identified from 2000 to 2002 in the Nurses' Health Study and 2001 to 2003 in the Nurses' Health Study II. We pooled data from the 2 cohorts, and estimated odds ratios and 95% confidence intervals using multivariable logistic regression adjusting for age, parity, body mass index, smoking, hysterectomy, functional limitations, menopausal status, postmenopausal hormone use, incontinence promoting medications and study cohort. RESULTS The incidence of at least weekly urinary incontinence was 5.3% (3,612 of 67,984) among women without type 2 diabetes and 8.7% (318 of 3,666) among women with diabetes. Overall the multivariable adjusted odds of incident urinary incontinence were increased 20% (OR 1.2, 95% CI 1.0-1.3, p = 0.01) among women with vs without type 2 diabetes. This increase appeared largely explained by significantly greater odds of urge urinary incontinence (OR 1.4, 95% CI 1.0-1.9, p = 0.03). There was no apparent association between diabetes and stress (p = 0.3) or mixed (p = 0.6) urinary incontinence, although confidence intervals were somewhat wide. CONCLUSIONS Our findings suggest that type 2 diabetes may especially influence urge urinary incontinence. Further research is needed to confirm this finding and identify pathways linking these conditions.
This paper references
10.1111/j.1532-5415.2005.53565.x
Type 2 Diabetes Mellitus and Risk of Developing Urinary Incontinence
K. Lifford (2005)
10.1111/J.1474-8673.2006.00371.X
Muscarinic receptor function, density and G-protein coupling in the overactive diabetic rat bladder.
L. Stevens (2006)
10.1016/S0029-7844(02)02241-X
Urinary Incontinence Predictors and Life Impact in Ethnically Diverse Perimenopausal Women
C. Sampselle (2002)
10.1007/s001920070021
Epidemiology and Natural History of Urinary Incontinence
S. Hunskaar (2000)
10.1016/S0022-5347(01)66768-5
Preference, compliance and initial outcome of therapeutic options chosen by female patients with urinary incontinence.
A. Diokno (1995)
10.1016/S0029-7844(99)00263-X
Prevalence of urinary incontinence and associated risk factors in postmenopausal women
J. Brown (1999)
10.1080/00016340701625347
Diabetes and urinary incontinence – prevalence data from Norway
Marit Helen Ebbesen (2007)
10.1016/0895-4356(94)00147-I
Diagnostic classification of female urinary incontinence: an epidemiological survey corrected for validity.
H. Sandvik (1995)
10.1093/AJE/KWK018
Factors associated with prevalent and incident urinary incontinence in a cohort of midlife women: a longitudinal analysis of data: study of women's health across the nation.
L. E. Waetjen (2007)
10.1016/0140-6736(91)90664-B
Physical activity and incidence of non-insulin-dependent diabetes mellitus in women
J. Manson (1991)
10.1016/0029-7844(96)00013-0
Urinary Incontinence in Older Women: Who Is at Risk?
J. Brown (1996)
10.1111/j.1532-5415.1996.tb02936.x
Urinary Incontinence in Rural Older Women: Prevalence, Incidence and Remission
I. Nygaard (1996)
10.2337/dc05-2463
Prevalence and Risk Factors for Urinary Incontinence in Women With Type 2 Diabetes and Impaired Fasting Glucose
J. Brown (2006)
10.1007/s00192-005-1359-5
Ultra-structural morphological abnormalities of the urinary bladder in streptozotocin-induced diabetic female rats
D. Rizk (2005)
10.1016/S0022-5347(17)41720-4
Clinical and cystometric characteristics of continent and incontinent noninstitutionalized elderly.
A. Diokno (1988)
10.1001/ARCHINTE.161.13.1581
Impact of overweight on the risk of developing common chronic diseases during a 10-year period.
A. Field (2001)
10.1093/AGEING/AFI205
Urinary storage symptoms and comorbidities: a prospective population cohort study in middle-aged and older women.
C. McGrother (2006)
10.1016/J.AJOG.2007.03.041
Incidence and remission of urinary incontinence in middle-aged women.
M. Townsend (2007)



This paper is referenced by
10.1007/s11884-014-0255-6
Is the Diabetic Bladder a Neurogenic Bladder? Evidence from the Literature
C. Powell (2014)
10.1016/j.ajog.2009.11.021
The incidence of urinary incontinence across Asian, black, and white women in the United States.
M. Townsend (2010)
10.1007/s00192-014-2489-4
Clinical risk factors and urodynamic predictors prior to surgical treatment for stress urinary incontinence: a narrative review
M. H. Bing (2014)
10.1111/jocn.12392
Urinary incontinence among adult women with diabetes in Jordan: epidemiology, correlates and perceived impact on emotional and social well-being.
Wegdan Bani-Issa (2014)
10.1097/WON.0000000000000259
Lower Urinary Tract Symptoms in Women With Type 2 Diabetes Mellitus
Sema Dereli Yilmaz (2016)
10.1186/1471-2318-14-137
Predictors of urinary incontinence in community-dwelling frail older adults with diabetes mellitus in a cross-sectional study
Amy Hsu (2014)
10.3978/j.issn.2223-4683.2016.01.02
Not all neurogenic bladders are the same: a proposal for a new neurogenic bladder classification system
Charles R.H. Powell (2016)
10.1111/ijcp.12196
Does concomitant diabetes affect treatment responses in overactive bladder patients?
T. Schneider (2013)
10.2147/TCRM.S125781
Effects of bariatric surgery on urinary incontinence
N. Bulbuller (2017)
Obesity stress urInary IncontInence aMong woMen partIcIpatIng In the faMIly health prograM of dourados ( Ms ) , brazIl
Guido Vieira Gomes ()
10.1111/jocn.12176
Urinary incontinence in Emirati women with diabetes mellitus type 2: prevalence, risk factors and impact on life.
Wegdan Bani-Issa (2013)
10.1016/j.purol.2012.10.009
[Urinary disorders and metabolic syndrome: prospective study].
S. Boudokhane (2013)
10.1007/978-1-62703-092-2_8
Female Urinary Incontinence
Christopher K. Payne (2012)
10.1159/000320333
Prevalence and Related Factors of Urinary Incontinence among Hebei Women of China
X. Wu (2011)
Examining neglected health problems in women at mid-life in Bangladesh
Md. Rakibul Islam (2016)
10.1007/s00192-012-1785-0
Diabetes mellitus and female urinary incontinence: a time for change
Mohamed Abdel-fattah (2012)
10.1586/EOG.10.48
Postpartum stress urinary incontinence: lessons from animal models.
Bradley C. Gill (2010)
10.1016/j.ajog.2011.02.047
Association between metabolic syndrome and pelvic floor dysfunction in middle-aged to older Korean women.
Y. Kim (2011)
10.1016/j.ajog.2015.08.072
Bridging the gap: determinants of undiagnosed or untreated urinary incontinence in women.
E. Duralde (2016)
10.1007/s11934-011-0215-z
Risk Factors for the Development of Stress Urinary Incontinence in Women
L. Stothers (2011)
Genintourinary Oncology Urinary incontinence after high-dose-rate brachytherapy boost treatment for prostate cancer
Borut Kragelj (2016)
The link between chronic conditions and urinary incontinence
Pauline Chiarelli (2010)
10.1111/iju.12654
Long‐term prevalence and predictors of urinary incontinence among women in the Diabetes Prevention Program Outcomes Study
S. Phelan (2015)
10.1101/246462
Vascular risk factors for male and female urgency urinary incontinence at age 68 from a British birth cohort study
Alex Tsui (2018)
10.1016/J.PUROL.2015.09.003
Le retentissement du diabète sur le bas appareil urinaire : une revue du comité de neuro-urologie de l’Association française d’urologie
G. Capon (2016)
10.1111/1471-0528.15897
Body mass index, abdominal fatness, weight gain and the risk of urinary incontinence: a systematic review and dose–response meta‐analysis of prospective studies
D. Aune (2019)
10.3109/9781439807217-3
Epidemiology: U.S.A.
Scott E. Kalinowski (2010)
10.1016/S1957-2557(15)30231-5
Troubles vésico-sphinctériens et syndrome métabolique
Aziza Nait Khachat (2015)
10.1016/j.juro.2015.06.074
Biochemical Measures of Diabetes are Not Independent Predictors of Urinary Incontinence in Women.
A. Weinberg (2015)
Associação entre os distúrbios hiperglicêmicos e a ocorrência de incontinência urinária e sua influência na qualidade de vida durante a gestação
A. Carolina (2011)
KNGF Guideline for Physical Therapy in patients with Stress urinary incontinence
(2013)
10.5016/dt000612224
Alterações morfológicas das fibras I e II do músculo estriado uretral de ratas prenhes diabéticas
G. Marini (2010)
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