Online citations, reference lists, and bibliographies.
← Back to Search

Microplastics Negatively Impact Embryogenesis And Modulate The Immune Response Of The Marine Medaka Oryzias Melastigma.

Jincan Chen, Mengyun Chen, Chao Fang, R. Zheng, Yulu Jiang, Yusheng Zhang, Ke‐jian Wang, C. Bailey, H. Segner, J. Bo
Published 2020 · Medicine, Biology

Save to my Library
Download PDF
Analyze on Scholarcy Visualize in Litmaps
Share
Reduce the time it takes to create your bibliography by a factor of 10 by using the world’s favourite reference manager
Time to take this seriously.
Get Citationsy
Microplastic (MP) pollution is an emerging contaminant in aquatic environments worldwide. Nonetheless, the developmental toxicity of MPs in the early life stages of fish and the mechanisms involved are not yet fully understood. The present study investigated the effects of different concentrations of polystyrene (PS) MPs on the early development of the marine model fish the medaka Oryzias melastigma. Our results showed that waterborne exposure to PS MPs significantly delayed the hatching time, altered the heartbeat and decreased the hatching rate of embryos. Furthermore, the genes involved in cardiac development, encoding for embryo-hatching enzymes, as well as inflammatory responses were significantly upregulated. The transcriptome results showed that mainly the pathways involved in metabolism, immune response, genetic information processing and diseases were significantly enriched. These results demonstrate that PS MPs negatively impact embryogenesis and the immune response of O. melastigma.
This paper references
10.1016/0091-6749(91)90007-B
Mucus secretagogue production by a human macrophage hybridoma.
K. Sperber (1991)
10.1016/0091-6749(92)90376-D
Isolation and characterization of a macrophage-derived high molecular weight protein involved in the regulation of mucus-like glycoconjugate secretion.
E. Gollub (1992)
10.1165/AJRCMB.11.2.8049080
Platelet-activating factor induces airway mucin release via activation of protein kinase C: evidence for translocation of protein kinase C to membranes.
P. Larivée (1994)
10.1042/BJ3340297
Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway.
P. Heinrich (1998)
10.1101/GAD.14.15.1837
Wnt signaling and cancer.
P. Polakis (2000)
Up-regulation of mucin secretion in HT29-MTX cells by the pro-inflammatory cytokines tumor necrosis factor-alpha and interleukin-6.
M. G. Smirnova (2001)
10.1016/S0378-1119(02)00398-0
Signaling through the JAK/STAT pathway, recent advances and future challenges.
T. Kisseleva (2002)
IARC (2002)
10.1073/pnas.1530509100
Statistical significance for genomewide studies
John D. Storey (2003)
10.1016/j.mod.2004.03.012
Stages of normal development in the medaka Oryzias latipes
T. Iwamatsu (2004)
10.1073/PNAS.0400752101
GATA4 is essential for formation of the proepicardium and regulates cardiogenesis.
A. Watt (2004)
10.1093/bioinformatics/bti430
Automated genome annotation and pathway identification using the KEGG Orthology (KO) as a controlled vocabulary
X. Mao (2005)
10.1016/J.YDBIO.2006.11.020
The roles of Groucho/Tle in left-right asymmetry and Kupffer's vesicle organogenesis.
B. Bajoghli (2007)
Effect of proinflammatory cytokines on the human MUC5AC promoter activity in vitro and in vivo
I. Wang (2007)
10.1002/IEAM.5630030412
Microplastic--an emerging contaminant of potential concern?
M. Browne (2007)
10.1093/nar/gkm882
KEGG for linking genomes to life and the environment
M. Kanehisa (2008)
10.1016/j.toxlet.2008.08.003
Effects of repeated silver nanoparticles exposure on the histological structure and mucins of nasal respiratory mucosa in rats.
J. Hyun (2008)
10.1016/J.AQUATOX.2007.10.011
Development of a marine fish model for studying in vivo molecular responses in ecotoxicology.
R. Kong (2008)
10.1038/nmeth.1226
Mapping and quantifying mammalian transcriptomes by RNA-Seq
A. Mortazavi (2008)
10.1016/j.devcel.2009.06.016
Wnt/beta-catenin signaling: components, mechanisms, and diseases.
B. Macdonald (2009)
10.1016/j.aquatox.2009.05.008
New cytochrome P450 1B1, 1C2 and 1D1 genes in the killifish Fundulus heteroclitus: Basal expression and response of five killifish CYP1s to the AHR agonist PCB126.
J. Zanette (2009)
10.1161/CIRCRESAHA.110.217950
Tbx5 and Bmp Signaling Are Essential for Proepicardium Specification in Zebrafish
Jiandong Liu (2010)
10.1186/gb-2010-11-10-r106
Differential expression analysis for sequence count data
S. Anders (2010)
10.1038/nbt.1883
Full-length transcriptome assembly from RNA-Seq data without a reference genome.
M. Grabherr (2011)
10.1038/emboj.2011.4
Drosophila Ras/MAPK signalling regulates innate immune responses in immune and intestinal stem cells
A. Ragab (2011)
10.1016/j.aquatox.2011.05.012
Perfluorooctane sulfonate impairs the cardiac development of a marine medaka (Oryzias melastigma).
Qiansheng Huang (2011)
10.1016/j.marpolbul.2011.05.014
The marine medaka Oryzias melastigma--a potential marine fish model for innate immune study.
J. Bo (2011)
10.1186/1471-2105-12-323
RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome
Bo Li (2011)
Toxic effects of cadmium, mercury, chromium and lead on the early life stage of marine medaka (Oryzias melastigma)
Mu (2011)
10.1016/j.molimm.2011.12.008
IL-4 regulates chemokine CCL26 in keratinocytes through the Jak1, 2/Stat6 signal transduction pathway: Implication for atopic dermatitis.
L. Bao (2012)
10.1016/j.chemosphere.2011.12.060
PFOS induced precocious hatching of Oryzias melastigma--from molecular level to individual level.
X. Wu (2012)
10.1016/j.cbd.2012.02.005
Identification of differentially expressed genes and quantitative expression of complement genes in the liver of marine medaka Oryzias melastigma challenged with Vibrio parahaemolyticus.
J. Bo (2012)
IARC (2012)
10.1021/es401932b
Size-dependent effects of micro polystyrene particles in the marine copepod Tigriopus japonicus.
Kyun-Woo Lee (2013)
10.1021/es403605f
Polystyrene plastic: a source and sink for polycyclic aromatic hydrocarbons in the marine environment.
C. Rochman (2013)
10.5772/55187
Why are Early Life Stages of Aquatic Organisms more Sensitive to Toxicants than Adults
A. Mohammed (2013)
10.3109/08977194.2012.752737
The way Wnt works: Components and mechanism
Kenyi Saito-Diaz (2013)
10.1016/j.envpol.2013.02.031
The physical impacts of microplastics on marine organisms: a review.
S. Wright (2013)
Mohammed (2013)
10.1016/j.envpol.2013.10.036
The present and future of microplastic pollution in the marine environment.
J. A. Ivar do Sul (2014)
10.1289/ehp.123-A34
New Link in the Food Chain? Marine Plastic Pollution and Seafood Safety
Nate Seltenrich (2015)
10.1007/s00244-015-0209-9
Occurrence and Distribution of Microplastics in the Sea Surface Microlayer in Jinhae Bay, South Korea
Young Kyoung Song (2015)
10.1016/j.marenvres.2015.09.009
Evaluation of the impact of polyethylene microbeads ingestion in European sea bass (Dicentrarchus labrax) larvae.
D. Mazurais (2015)
10.1016/j.envpol.2015.05.025
"Plastic ocean": What about cancer?
T. Erren (2015)
10.1016/j.marpolbul.2015.06.008
Microplastics in the marine environment: Current trends and future perspectives.
L. G. A. Barboza (2015)
10.1021/acs.est.6b01441
Microplastic Size-Dependent Toxicity, Oxidative Stress Induction, and p-JNK and p-p38 Activation in the Monogonont Rotifer (Brachionus koreanus).
Chang-Bum Jeong (2016)
10.1073/pnas.1519019113
Oyster reproduction is affected by exposure to polystyrene microplastics
R. Sussarellu (2016)
10.1021/acs.est.6b00183
Uptake and Accumulation of Polystyrene Microplastics in Zebrafish (Danio rerio) and Toxic Effects in Liver.
Y. Lu (2016)
10.1002/tox.22028
Accumulation of di(2‐ethylhexyl) phthalate causes endocrine‐disruptive effects in marine medaka (Oryzias melastigma) embryos
T. Ye (2016)
PlasticsEurope (2016)
10.1016/j.marpolbul.2017.02.030
Assessing the toxicity of triphenyltin to different life stages of the marine medaka Oryzias melastigma through a series of life-cycle based experiments.
Xianliang Yi (2017)
10.1016/j.aquatox.2017.01.006
The embryotoxicity of ZnO nanoparticles to marine medaka, Oryzias melastigma.
Y. Cong (2017)
10.1016/j.marpolbul.2016.12.055
Assessment of microplastic-sorbed contaminant bioavailability through analysis of biomarker gene expression in larval zebrafish.
V. Sleight (2017)
10.1016/j.envint.2017.01.018
Microplastics en route: Field measurements in the Dutch river delta and Amsterdam canals, wastewater treatment plants, North Sea sediments and biota.
H. Leslie (2017)
10.1080/10408444.2017.1288024
20 Years of fish immunotoxicology – what we know and where we are
Kristina Rehberger (2017)
10.1016/j.envpol.2017.03.062
Microplastic ingestion in fish larvae in the western English Channel.
M. Steer (2017)
10.1002/ieam.1913
Ingestion of microplastics by fish and its potential consequences from a physical perspective.
B. Jovanović (2017)
10.1074/jbc.M117.775304
Ets homologous factor (EHF) has critical roles in epithelial dysfunction in airway disease
S. Fossum (2017)
10.1038/srep40777
A transcriptome analysis focusing on inflammation-related genes of grass carp intestines following infection with Aeromonas hydrophila
Xuehong Song (2017)
10.1016/B978-0-323-35214-7.00130-X
130 – Neonatal Pulmonary Host Defense
M. Good (2017)
10.1016/j.fsi.2017.10.029
Viral infections in common carp lead to a disturbance of mucin expression in mucosal tissues
M. Adamek (2017)
10.1038/srep41323
Adverse effects of microplastics and oxidative stress-induced MAPK/Nrf2 pathway-mediated defense mechanisms in the marine copepod Paracyclopina nana
Chang-Bum Jeong (2017)
Neonatal pulmonary host defense
Good (2017)
10.1016/j.envpol.2017.12.088
Polystyrene microplastics induce microbiota dysbiosis and inflammation in the gut of adult zebrafish.
Yuanxiang Jin (2018)
10.1007/s11356-017-1141-5
Effects of glyphosate on early life stages: comparison between Cyprinus carpio and Danio rerio
E. Fiorino (2018)
10.1016/j.scitotenv.2018.06.257
Effects of nanoplastics on Mytilus galloprovincialis after individual and combined exposure with carbamazepine.
I. Brandts (2018)
10.1016/j.aquatox.2017.11.017
Uptake, tissue distribution, and toxicity of polystyrene nanoparticles in developing zebrafish (Danio rerio).
Jordan A Pitt (2018)
10.1016/j.scitotenv.2018.03.046
A meta-analysis of the effects of exposure to microplastics on fish and aquatic invertebrates.
Carolyn J. Foley (2018)
10.1021/acs.est.8b00168
Microplastics Affect Energy Balance and Gametogenesis in the Pearl Oyster Pinctada margaritifera.
Tony Gardon (2018)
10.1016/j.envpol.2018.08.084
Transcriptional effects of polyethylene microplastics ingestion in developing zebrafish (Danio rerio).
C. M. LeMoine (2018)
10.1016/j.chemosphere.2018.06.101
Microplastic contamination in benthic organisms from the Arctic and sub-Arctic regions.
Chao Fang (2018)
10.1007/s11356-018-3497-6
Accumulation and immunotoxicity of microplastics in the estuarine worm Hediste diversicolor in environmentally relevant conditions of exposure
M. Revel (2018)
10.1016/j.critrevonc.2017.12.006
Mucins: Structural diversity, biosynthesis, its role in pathogenesis and as possible therapeutic targets.
S. S. Dhanisha (2018)
10.1016/j.jhazmat.2019.121586
Low level of polystyrene microplastics decreases early developmental toxicity of phenanthrene on marine medaka (Oryzias melastigma).
Yuejiao Li (2019)
10.1016/J.ENVPOL.2019.113024
Polystyrene microplastics cause tissue damages, sex-specific reproductive disruption and transgenerational effects in marine medaka (Oryzias melastigma).
J. Wang (2019)
10.1016/j.etap.2019.03.001
Microplastics in the marine environment: Current trends in environmental pollution and mechanisms of toxicological profile.
C. Alimba (2019)
10.1016/J.ENVPOL.2019.04.063
Benzo[a]pyrene (BaP) exposure generates persistent reactive oxygen species (ROS) to inhibit the NF-κB pathway in medaka (Oryzias melastigma).
Qian Cui (2019)
10.1039/c8nr09326a
A generalized strategy for the synthesis of two-dimensional metal oxide nanosheets based on a thermoregulated phase transition.
Jianming Zhang (2019)
10.1002/lol2.10127
Patterns of suspended and salp‐ingested microplastic debris in the North Pacific investigated with epifluorescence microscopy
Jennifer A. Brandon (2019)
10.1016/j.marpolbul.2019.110510
Effects of microplastics and attached heavy metals on growth, immunity, and heavy metal accumulation in the yellow seahorse, Hippocampus kuda Bleeker.
Sun Jinhui (2019)
10.1016/j.chemosphere.2019.04.098
Ingestion, egestion and post-exposure effects of polystyrene microspheres on marine medaka (Oryzias melastigma).
Y. Cong (2019)
10.1016/j.ecoenv.2019.109442
Acute toxic effects of polyethylene microplastic on adult zebrafish.
C. Mak (2019)
10.1016/j.envpol.2019.113011
Microplastics in the environment: A critical review of current understanding and identification of future research needs.
Zeynep Akdoğan (2019)
10.1039/c8nr09321k
Bioaccumulation of polystyrene nanoplastics and their effect on the toxicity of Au ions in zebrafish embryos.
W. Lee (2019)
10.1016/J.TRAC.2018.10.025
Micro- (nano) plastics in freshwater ecosystems: Abundance, toxicological impact and quantification methodology
S. Strungaru (2019)
10.1038/s41598-019-52292-5
Microplastics induce transcriptional changes, immune response and behavioral alterations in adult zebrafish
G. Limonta (2019)
10.1016/j.envint.2019.105047
Environmental samples of microplastics induce significant toxic effects in fish larvae.
P. Pannetier (2019)
State Oceanic Administration of China
China Petroleum and Chemical Industry Federation



This paper is referenced by
Semantic Scholar Logo Some data provided by SemanticScholar