The Material Mapping Strategy Influences The Accuracy Of CT-based Finite Element Models Of Bones: An Evaluation Against Experimental Measurements.
F. Taddei, E. Schileo, B. Helgason, L. Cristofolini, M. Viceconti
Published 2007 · Engineering, Medicine
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Aim of the present study was to evaluate the influence on the global model's accuracy of the strategy adopted to define the average element Young's modulus in subject-specific finite element models of bones from computed tomography data. The classic strategy of calculating the Young's modulus from an average element density and the one that averages the Young's moduli directly derived from each voxel Hounsfield Unit were considered. These strategies were applied to the finite element model of a real human femur. The accuracy of the superficial stress and strain predictions was evaluated against experimentally measured values in 13 strain-gauge locations for five different loading conditions. The results obtained for the two material distributions were statistically different. Both models predicted very accurately the superficial stresses, with regression coefficients higher than 0.9 and slopes not significantly different from unity. The second strategy definitely improved the strains prediction accuracy: the regression coefficient raised from 0.69 to 0.79; the average and peak errors decreased from 45.1% to 31.3% and from 228% to 134% of the maximum measured strain, respectively. The stress fields predicted inside the bone were also significantly different. A new software implementing the second strategy was made available in the public domain.
This paper references
Quantitative CT for determination of bone mineral density: a review.
C. Cann (1988)
A phantom for standardization and quality control in spinal bone mineral measurements by QCT and DXA: design considerations and specifications.
W. Kalender (1992)
Automated three-dimensional finite element modelling of bone: a new method.
J. Keyak (1990)
A comparison between automatically generated linear and parabolic tetrahedra when used to mesh a human femur
K. Polgár (2001)
Development and experimental validation of a three-dimensional finite element model of the human scapula
S. Gupta (2004)
Subject-specific finite element models of long bones: An in vitro evaluation of the overall accuracy.
F. Taddei (2006)
A Method for Registration of 3-D Shapes
P. Besl (1992)
Fracture simulation of the femoral bone using the finite-element method: How a fracture initiates and proceeds
T. Ota (1999)
Automatic generation of accurate subject-specific bone finite element models to be used in clinical studies.
M. Viceconti (2004)
Comparison of geometry-based and CT voxel-based finite element modelling and experimental validation.
M. Lengsfeld (1998)
Beam hardening in x-ray reconstructive tomography.
R. Brooks (1976)
Mechanical properties of trabecular bone from the proximal femur: a quantitative CT study.
J. C. Lotz (1990)
Automatic generation of finite element meshes from computed tomography data.
M. Viceconti (2003)
Predicting the compressive mechanical behavior of bone.
T. Keller (1994)
Border-tracing algorithm implementation for the femoral geometry reconstruction
D. Testi (2001)
Estimation of material properties in the equine metacarpus with use of quantitative computed tomography.
C. Les (1994)
Development and validation of a three-dimensional finite element model of the pelvic bone.
M. Dalstra (1995)
Validation of an automated method of three-dimensional finite element modelling of bone.
J. Keyak (1993)
The compressive behavior of bone as a two-phase porous structure.
D. Carter (1977)
Finite element models predict in vitro vertebral body compressive strength better than quantitative computed tomography.
R. Crawford (2003)
Material properties assignment to finite element models of bone structures: a new method.
C. Zannoni (1998)
The effect of muscle loading on the simulation of bone remodelling in the proximal femur.
C. Bitsakos (2005)
An improved method for the automatic mapping of computed tomography numbers onto finite element models.
F. Taddei (2004)
Improved prediction of proximal femoral fracture load using nonlinear finite element models.
J. Keyak (2001)
Short Term In Vivo Precision of Proximal Femoral Finite Element Modeling
Dianna D. Cody (2004)
A combined RSA and FE study of the implanted proximal tibia: correlation of the post-operative mechanical environment with implant migration.
A. Perillo-Marcone (2004)
A new method to compare planned and achieved position of an orthopaedic implant
F. Popescu (2003)
The effect of impact direction on the structural capacity of the proximal femur during falls
C. M. Ford (1996)
Influence of thigh muscles on the axial strains in a proximal femur during early stance in gait.
L. Cristofolini (1995)
Effect of local density changes on the failure load of the proximal femur.
Z. M. Oden (1999)
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María Angeles Pérez (2010)
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Caroline A. Grant (2014)
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Yunhua Luo (2015)
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Inhomogeneous material property assignment and orientation definition of transverse isotropy of femur
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Femur finite element model instantiation from partial anatomies using statistical shape and appearance models.
Daniel Nolte (2019)
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R. Austman (2008)
Orientation of orthotropic material properties in a femur FE model: a method based on the principal stresses directions.
T. San Antonio (2012)
Diminished response to in vivo mechanical loading in trabecular and not cortical bone in adulthood of female C57Bl/6 mice coincides with a reduction in deformation to load.
B. Willie (2013)
Biomechanical robustness of a new proximal epiphyseal hip replacement to patient variability and surgical uncertainties: a FE study.
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