Please confirm you are human (Sign Up for free to never see this)
← Back to Search
Functional MRI Of Oropharyngeal Air-pulse Stimulation
Peter Sörös, E. Lalone, R. Smith, T. Stevens, R. Martin
Published 2008 · Psychology, Medicine
Save to my Library
Download PDFAnalyze on Scholarcy
Although the posterior oral cavity and oropharynx play a major role in swallowing, their central representation is poorly understood. High-field functional magnetic resonance imaging of the brain was used to study the central processing of brief air-pulses, delivered to the peritonsillar region of the lateral oropharynx, in six healthy adults. Bilateral air-pulse stimulation was associated with the activation of a bilateral network including the primary somatosensory cortex and the thalamus, classic motor areas (primary motor cortex, supplementary motor area, cingulate motor areas), and polymodal areas (including the insula and frontal cortex). These results suggest that oropharyngeal stimulation can activate a bilaterally distributed cortical network that overlaps cortical regions previously implicated in oral and pharyngeal sensorimotor functions such as tongue movement, mastication, and swallowing. The present study also demonstrates the utility of air-pulse stimulation in investigating oropharyngeal sensorimotor processing in functional brain imaging experiments.
This paper references
Anatomic correlates of the face and oral cavity representations in the somatosensory cortical area 3b of monkeys
N. Jain (2001)
Postacquisition suppression of large‐vessel BOLD signals in high‐resolution fMRI
R. Menon (2002)
Cortical and thalamic connections of the representations of the teeth and tongue in somatosensory cortex of new world monkeys
Soumya Iyengar (2007)
Fast robust automated brain extraction
S. Smith (2002)
Aging of the Somatosensory System: A Translational Perspective
S. Shaffer (2007)
Establishing a reliable protocol to measure tongue sensation.
C. Boliek (2007)
Neural Organization of Swallowing
Takemoto Shin (1998)
Clustered functional MRI of overt speech production
Peter Sörös (2006)
Mechanisms of oral sensation
N. Capra (2004)
Somatosensory evoked magnetic fields to air-puff stimulation on the soft palate
K. Yoshida (2006)
Bilateral cortical representation of the trunk midline in human first somatic sensory area
M. Fabri (2005)
Temporal Autocorrelation in Univariate Linear Modeling of FMRI Data
M. Woolrich (2001)
A transmit‐only/receive‐only (TORO) RF system for high‐field MRI/MRS applications
E. Barberi (2000)
Oral stereognosis: a review of the literature
R. Jacobs (1998)
Oral cavity representation at the frontal operculum of macaque monkeys
H. Ogawa (1989)
Short-latency components of evoked potentials to median nerve stimulation recorded by intracerebral electrodes in the human pre- and postcentral areas
E. Balzamo (2004)
Somatotopic organization of human secondary somatosensory cortex.
J. Ruben (2001)
Coordination of mastication and swallowing
J. Palmer (2006)
Short and middle-latency Median Nerve (MN) SEPs recorded by depth electrodes in human pre-SMA and SMA-proper
C. Barba (2005)
Representations of the face, teeth and oral cavity in areas 3b and 1 of somatosensory cortex in squirrel monkeys
C. Cusick (1986)
Ipsilateral cortical projections to areas 3a, 3b, and 4 in the macaque monkey
C. Darian-Smith (1993)
Improved Optimization for the Robust and Accurate Linear Registration and Motion Correction of Brain Images
M. Jenkinson (2002)
Input-output relationships of the primary face motor cortex in the monkey (Macaca fascicularis).
C. Huang (1989)
Magnetic sensory cortical responses evoked by tactile stimulations of the human face, oral cavity and flap reconstructions of the tongue
H. Yamashita (1999)
The supplementary motor area in the cerebral cortex of man
W. Penfield (2004)
Anatomy of the insula functional and clinical correlates
Frederick G. Flynn (1999)
Cortical Activation Resulting from Painless Vibrotactile Dental Stimulation Measured by Functional Magnetic Resonance Imaging (fMRI)
D. Ettlin (2004)
Reduction of signal fluctuation in functional MRI using navigator echoes
X. Hu (1994)
Motor areas in the frontal lobe of the primate
R. Dum (2002)
Organization of the primate face motor cortex as revealed by intracortical microstimulation and electrophysiological identification of afferent inputs and corticobulbar projections.
C. Huang (1988)
Mechanisms of oral somatosensory and motor functions and their clinical correlates.
B. Sessle (2006)
The representation of the human oral area in the somatosensory cortex: a functional MRI study.
J. Miyamoto (2006)
Dysphagia following stroke: quantitative evaluation of pharyngeal transit times.
E. Johnson (1992)
Brain stem control of swallowing: neuronal network and cellular mechanisms.
A. Jean (2001)
Long-term chronic multichannel recordings from sensorimotor cortex and thalamus of primates.
N. Jain (2001)
Taste responses of cortical neurons in freely ingesting rats.
T. Yamamoto (1989)
Single unit responses of human cutaneous mechanoreceptors to air-puff stimulation
K. Mizobuchi (2000)
Thermosensory activation of insular cortex
A. Craig (2000)
Somatosensory Homunculus as Drawn by MEG
A. Nakamura (1998)
Effects of reversible inactivation by cooling of the primate face motor cortex on the performance of a trained tongue-protrusion task and a trained biting task.
G. Murray (1991)
Ipsilateral representation of oral structures in human anterior parietal somatosensory cortex and integration of inputs across the midline
E. Disbrow (2003)
Functional anatomy of the human supplementary sensorimotor area: results of extraoperative electrical stimulation.
S. H. Lim (1994)
Anteroposterior somatotopy of innocuous cooling activation focus in human dorsal posterior insular cortex.
Le H Hua (2005)
fMRI evidence for an inverted face representation in human somatosensory cortex.
P. Servos (1999)
Cortical Surface-Based Analysis: I. Segmentation and Surface Reconstruction
A. Dale (1999)
Cortical activation induced by intraoral stimulation with water in humans.
D. Zald (2000)
Evaluation and treatment of swallowing disorders
J. Logemann (1983)
Functional organization of trigeminal subnucleus interpolaris: nociceptive and innocuous afferent inputs, projections to thalamus, cerebellum, and spinal cord, and descending modulation from periaqueductal gray.
H. Hayashi (1984)
Cerebral cortical processing of swallowing in older adults
R. Martin (2006)
Functional MRI study of thalamic and cortical activations evoked by cutaneous heat, cold, and tactile stimuli.
K. Davis (1998)
Submodality distribution in sensorimotor cortex of the unanesthetized monkey.
J. Tanji (1981)
The neural mechanisms of gustation: a distributed processing code
S. Simon (2006)
Oropharyngeal Stimulation with Air-Pulse Trains Increases Swallowing Frequency in Healthy Adults
J. Theurer (2005)
Functional MRI of working memory and selective attention in vibrotactile frequency discrimination
Peter Sörös (2007)
Book Review: Bilateral Activity and Callosal Connections in the Somatosensory Cortex
Y. Iwamura (2001)
Clinical assessment of pharyngolaryngeal sensitivity.
J. Aviv (2000)
Probabilistic independent component analysis for functional magnetic resonance imaging
C. Beckmann (2004)
Representation of face and intra‐oral structures in area 3b of macaque monkey somatosensory cortex
P. Manger (1996)
Features of cortically evoked swallowing in the awake primate (Macaca fascicularis).
R. Martin (1999)
Surface Sensibility of the Floor of the Mouth and Tongue in Healthy Controls and in Radiated Patients
J. Aviv (1992)
The Cerebral Cortex of Man: A Clinical Study of Localization of Function
W. Penfield (1950)
Representation of the midline trunk, bilateral arms, and shoulders in the monkey postcentral somatosensory cortex
M. Taoka (1998)
Cerebral areas processing swallowing and tongue movement are overlapping but distinct: a functional magnetic resonance imaging study.
R. Martin (2004)
Long-term reorganization of human motor cortex driven by short-term sensory stimulation
S. Hamdy (1998)
Functional properties of single neurons in the primate face primary somatosensory cortex. I. Relations with trained orofacial motor behaviors.
L. Lin (1994)
Air Pulse Quantification of Supraglottic and Pharyngeal Sensation: A New Technique
J. Aviv (1993)
Multilevel linear modelling for FMRI group analysis using Bayesian inference
M. Woolrich (2004)
Regional brain activation during proximal stomach distention in humans: A positron emission tomography study.
Joris Vandenbergh (2005)
Localization of Palatal Area in Human Somatosensory Cortex
H. Bessho (2007)
This paper is referenced by
Safety and feasibility of above cuff vocalisation for ventilator-dependant patients with tracheostomies
B. McGrath (2019)
Exercise-based approaches to dysphagia rehabilitation.
C. Steele (2012)
Stuttered swallowing: Electric stimulation of the right insula interferes with water swallowing. A case report
Peter Sörös (2011)
Dysphagia after stroke and its management
R. Martino (2012)
Effects of Oropharyngeal Air-Pulse Stimulation on Swallowing in Healthy Older Adults
J. Theurer (2009)
Sour taste increases swallowing and prolongs hemodynamic responses in the cortical swallowing network.
Rachel W. Mulheren (2016)
Gastroenterology and Hepatology Research
Y. Yağmur (2015)
Comment on the article “Prevalence of probable obstructive sleep apnea risk and severity in a population of dental patients” by D.J. Levendowski et al.
M. Daulatzai (2009)
Cardiovascular and neurological causes of sudden death after ischaemic stroke
Peter Sörös (2012)
健常人の唾液嚥下時における脳活動 − functional MRI を用いた検討 −
朝則 喜友名 (2016)
Proof-of-principle pilot study of oropharyngeal air-pulse application in individuals with dysphagia after hemispheric stroke.
Julie A. Theurer (2013)
Age-related changes in the functional neuroanatomy of overt speech production
Peter Sörös (2011)
Neural activation of swallowing and swallowing‐related tasks in healthy young adults: An attempt to separate the components of deglutition
G. Malandraki (2009)
fMRI-Compatible Registration of Jaw Movements Using a Fiber-Optic Bend Sensor
Peter Sörös (2010)
Face sensorimotor cortex and its neuroplasticity related to orofacial sensorimotor functions.
L. Avivi-Arber (2011)
A Comparison of Vibrotactile and Air Puff Stimulation for Inducing Swallowing
K. D. White (2012)
Neurostimulation as an Approach to Dysphagia Rehabilitation: Current Evidence
E. Michou (2013)
Depicting the inner and outer nose: The representation of the nose and the nasal mucosa on the human primary somatosensory cortex (SI)
M. Gastl (2014)
History of the Use and Impact of Compensatory Strategies in Management of Swallowing Disorders
C. Lazarus (2016)
Motor Control and Biomechanics of Laryngeal and Pharyngeal Muscles
C. Ludlow (2012)
Speech-language pathology insights into genetics and neuroscience: Beyond surface behaviour
A. Morgan (2013)
Functional magnetic resonance imaging and swallowing : systematic review
Grolli Ardenghi (2016)
Role of Sensory Stimulation in Amelioration of Obstructive Sleep Apnea
M. Daulatzai (2011)
Chapter 21 - Dysphagia
G. Malandraki (2013)
Neurorehabilitation strategies for poststroke oropharyngeal dysphagia: from compensation to the recovery of swallowing function
C. Cabib (2016)
Cortical input in control of swallowing
E. Michou (2009)
Direct and Indirect Therapy: Neurostimulation for the Treatment of Dysphagia After Stroke
S. Mistry (2011)
Measurement of pharyngeal sensory cortical processing: technique and physiologic implications
I. Teismann (2008)
Voluntary Versus Spontaneous Swallowing in Man
C. Ertekin (2010)
Functional brain imaging of swallowing: An activation likelihood estimation meta‐analysis
Peter Sörös (2009)
An electrophysiological study of the sequential water swallowing.
N. Gürgör (2013)
Model-based and model-free analyses of the neural correlates of tongue movements
Peter Sörös (2019)See more