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Assessment Of Non-steroidal Anti-inflammatory And Analgesic Pharmaceuticals In Seawaters Of North Of Portugal: Occurrence And Environmental Risk.
A. Lolić, P. Paíga, L. Santos, S. Ramos, M. Correia, C. Delerue-Matos
Published 2015 · Environmental Science, Medicine
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The occurrence of seven pharmaceuticals and two metabolites belonging to non-steroidal anti-inflammatory drugs and analgesics therapeutic classes was studied in seawaters. A total of 101 samples covering fourteen beaches and five cities were evaluated in order to assess the spatial distribution of pharmaceuticals among north Portuguese coast. Seawaters were selected in order to embrace different bathing water quality (excellent, good and sufficient). Acetaminophen, ketoprofen and the metabolite hydroxyibuprofen were detected in all the seawater samples at maximum concentrations of 584, 89.7 and 287 ng L(-1), respectively. Carboxyibuprofen had the highest seawater concentration (1227 ng L(-1)). The temporal distribution of the selected pharmaceuticals during the bathing season showed that, in general, higher concentrations were detected in August and September. The environmental risk posed by the pharmaceuticals detected in seawaters towards different trophic levels (fish, daphnids and algae) was also assessed. Only diclofenac showed hazard quotients above one for fish, representing a potential risk for aquatic organisms. These results were observed in seawaters classified as excellent bathing water. Additional data is needed in order to support the identification and prioritization of risks posed by pharmaceuticals in marine environment.
This paper references
Selective degradation of ibuprofen and clofibric acid in two model river biofilm systems.
M. Winkler (2001)
Drugs and personal care products as ubiquitous pollutants: occurrence and distribution of clofibric acid, caffeine and DEET in the North Sea.
S. Weigel (2002)
Environmental risk assessment for new human pharmaceuticals in the European Union according to the draft guideline/discussion paper of January 2001.
J. O. Straub (2002)
Multi-residue analysis of pharmaceutical
A 131137–43.Togola (2002)
Aquatic ecotoxicity of pharmaceuticals including the assessment of combination effects.
M. Cleuvers (2003)
Determination of selected pharmaceuticals and caffeine in sewage and seawater from Tromsø/Norway with emphasis on ibuprofen and its metabolites.
S. Weigel (2004)
Mixture toxicity of the anti-inflammatory drugs diclofenac, ibuprofen, naproxen, and acetylsalicylic acid.
M. Cleuvers (2004)
Development of a multi-residue analytical methodology based on liquid chromatography-tandem mass spectrometry (LC-MS/MS) for screening and trace level determination of pharmaceuticals in surface and wastewaters.
M. Gros (2006)
Consequences of treated water recycling as regards pharmaceuticals and drugs in surface and ground waters of a medium-sized Mediterranean catchment.
M. Rabiet (2006)
Quantification of human pharmaceuticals in water samples by high performance liquid chromatography-tandem mass spectrometry.
C. Nebot (2007)
Development of a multi-residue
Chim. Acta (2007)
Individual and Mixture Effects of Selected Pharmaceuticals and Personal Care Products on the Marine Phytoplankton Species Dunaliella tertiolecta
M. DeLorenzo (2008)
Multi-residue analysis of pharmaceutical compounds in aqueous samples.
A. Togola (2008)
Fate and toxicity of emerging pollutants, their metabolites and transformation products in the aquatic environment
M. Farré (2008)
compounds in aqueous samples
M Al Aukidy (2008)
Evaluation of the acute, chronic and teratogenic effects of a mixture of eleven pharmaceuticals on the cnidarian, Hydra attenuata.
B. Quinn (2009)
Seasonal and Spatial Distribution of Several Endocrine-Disrupting Compounds in the Douro River Estuary, Portugal
C. Ribeiro (2009)
Seasonal and spatial distribution of several endocrine-disrupting compounds in the Douro River Estuary
C Ribeiro (2009)
Occurrence of polar organic contaminants in the dissolved water phase of the Danube River and its major tributaries using SPE-LC-MS(2) analysis.
R. Loos (2010)
Environmental risk assessment of pharmaceuticals in rivers: relationships between hazard indexes and aquatic macroinvertebrate diversity indexes in the Llobregat River (NE Spain).
A. Ginebreda (2010)
Validation and application of an LC-MS/MS method for the simultaneous quantification of 13 pharmaceuticals in seawater
K. Wille (2010)
Spatiotemporal distribution of pharmaceuticals in the Douro River estuary (Portugal).
T. Madureira (2010)
Study on the matrix effect in the determination of selected pharmaceutical residues in seawater by solid-phase extraction and ultra-high-performance liquid chromatography-electrospray ionization low-energy collision-induced dissociation tandem mass spectrometry.
Jingming Wu (2010)
Occurrence and transport of pesticides and alkylphenols in water samples along the Ebro River Basin
A. Navarro (2010)
Development of a multi-residue analytical method, based on liquid chromatography-tandem mass spectrometry, for the simultaneous determination of 46 micro-contaminants in aqueous samples.
Karsten Nödler (2010)
Environmental risk assessment of pharmaceuticals in rivers: relationships between hazard indexes and aquatic macroinvertebrate diversity indexes in the Llobregat River
A Ginebreda (2010)
The occurrence and fate of anti-inflammatory and analgesic
A Ziylan (2010)
contaminants in aqueous samples
LMLM Santos (2010)
Multiple imputation by chained equations: what is it and how does it work?
Melissa J Azur (2011)
The occurrence and fate of anti-inflammatory and analgesic pharmaceuticals in sewage and fresh water: treatability by conventional and non-conventional processes.
Asu Ziylan (2011)
Occurrence of pharmaceutical compounds in urban wastewater: removal, mass load and environmental risk after a secondary treatment--a review.
P. Verlicchi (2012)
The occurrence and distribution of pharmaceutical compounds in the effluents of a major sewage treatment plant in Northern Taiwan and the receiving coastal waters.
T. Fang (2012)
Fate of pharmaceuticals in rivers: Deriving a benchmark dataset at favorable attenuation conditions.
U. Kunkel (2012)
Endocrine disruptors in the Leça River and nearby Porto Coast (NW Portugal): presence of estrogenic compounds and hypoxic conditions
M. J. Rocha (2012)
Fast and comprehensive multi-residue analysis of a broad range of human and veterinary pharmaceuticals and some of their metabolites in surface and treated waters by ultra-high-performance liquid chromatography coupled to quadrupole-linear ion trap tandem mass spectrometry.
M. Gros (2012)
Integrated coastal effects study: synthesis of findings.
S. Bay (2012)
Pilot monitoring study of ibuprofen in surface waters of north of Portugal
P. Paíga (2012)
Comprehensive study of ibuprofen and its metabolites in activated sludge batch experiments and aquatic environment.
L. Ferrando-Climent (2012)
Contaminants of emerging concern in municipal wastewater effluents and marine receiving water.
D. Vidal-Dorsch (2012)
Drugs and personal care products
S Weigel (2012)
Pollution Pathways of Pharmaceutical Residues in the Aquatic Environment on the Island of Mallorca, Spain
C. Rodríguez-Navas (2013)
Quantification of 17 endocrine disruptor compounds and their spatial and seasonal distribution in the Iberian Ave River and its coastline
M. J. Rocha (2013)
EU-wide monitoring survey on emerging polar organic contaminants in wastewater treatment plant effluents.
R. Loos (2013)
Analysis of polar organic contaminants in surface water of the northern Adriatic Sea by solid-phase extraction followed by ultrahigh-pressure liquid chromatography–QTRAP® MS using a hybrid triple-quadrupole linear ion trap instrument
R. Loos (2013)
Non-steroidal anti-inflammatory drugs in Indian rivers
Govindaraj Shanmugam (2013)
Contribution of hospital effluents to the load of pharmaceuticals in urban wastewaters: identification of ecologically relevant pharmaceuticals.
L. Santos (2013)
Development of a simple analytical method for the simultaneous determination of paracetamol, paracetamol-glucuronide and p-aminophenol in river water.
L. Santos (2013)
Occurrence and distribution of pharmaceutically active and endocrine disrupting compounds in Singapore's marine environment: influence of hydrodynamics and physical-chemical properties.
S. Bayen (2013)
Analysis of acidic, basic and neutral pharmaceuticals in river waters: clean-up by 1°, 2° amino anion exchange and enrichment using an hydrophilic adsorbent
C. Gonçalves (2013)
Persistence of Ibuprofen, Ketoprofen, Diclofenac and Clofibric Acid in Natural Waters
L. Araujo (2014)
Environmental risk assessment for new human
Development of a SPE-UHPLC-MS/MS methodology for the determination of non-steroidal anti-inflammatory and analgesic pharmaceuticals in seawater.
P. Paíga (2015)
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Adsorption-desorption behavior of methylene blue onto aged polyethylene microplastics in aqueous environments.
Huimin You (2021)
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Agnieszka Grela (2021)
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Impacts of climate change-abiotic factors on the effects caused by pharmaceutical residues to marine organisms
Ângela Almeida (2021)
Sources and occurrence of pharmaceutical residues in offshore seawater
Nikiforos A. Alygizakis (2021)
Novel aqueous biphasic system based on ionic liquid for the simultaneous extraction of seven active pharmaceutical ingredients in aquatic environment
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Yiyuan Zhou (2021)
New sampling methods for detecting pharmaceutical residues in seawater and sediments
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Carbon paper as a promising sensing material: Characterization and electroanalysis of ketoprofen in wastewater and fish.
Á. Torrinha (2021)
Environmental protection by the adsorptive elimination of acetaminophen from water: A comprehensive review
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Emerging Contaminants in Seafront Zones. Environmental Impact and Analytical Approaches
J. Câmara (2021)
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Juliana F. Tisca (2021)
Effects of triclosan exposure on the energy budget of Ruditapes philippinarum and R. decussatus under climate change scenarios.
F. Maynou (2021)
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Ingrid Beate Øpstad Fredriksen (2021)
Removal of non-steroidal anti-inflammatory drugs from water by zeolite-rich composites: The interference of inorganic anions on the ibuprofen and naproxen adsorption.
D. Smiljanić (2021)
Strategies to remove pharmaceutical residues from seawater
Juan Carlos Durán-Álvarez (2021)
The present and future challenges in the development of multiresidue analytical methods for the determination of pharmaceuticals in seawater samples
Grzegorz Siedlewicz (2021)
High concentrations of paracetamol in effluent dominated waters of Jakarta Bay, Indonesia.
Wulan Koagouw (2021)
Fate and Effects of Anticancer Drugs in the Environment
T. Kosjek (2020)
Antioxidative and neurotoxicity effects of acute and chronic exposure of the estuarine polychaete Hediste diversicolor to paracetamol.
I. Barbosa (2020)
Sonochemical degradation of trimethoprim in water matrices: Effect of operating conditions, identification of transformation products and toxicity assessment.
O. Arvaniti (2020)
Pharmaceuticals and their metabolites in the marine environment: Sources, analytical methods and occurrence
L. M. Madikizela (2020)
Method Validation and Investigation of the Levels of Pharmaceuticals and Personal Care Products in Sludge of Wastewater Treatment Plants and Soils of Irrigated Golf Course
O. Ademoyegun (2020)
Occurrence and ecological risk assessment of pharmaceuticals and cocaine in a beach area of Guarujá, São Paulo State, Brazil, under the influence of urban surface runoff
Vinicius Roveri (2020)
Green Microalgae Scenedesmus Obliquus Utilization for the Adsorptive Removal of Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) from Water Samples
Andreia F R Silva (2020)
Use of Membrane for Removal of Nonsteroidal Anti-inflammatory Drugs
R. M. Gómez-Espinosa (2020)
Introduction and Historical Findings That Focused Nonsteroidal Anti-Inflammatory Drugs as Emerging Pollutant
Gustavo Axel Elizalde-Velázquez (2020)
Extended suspect screening to identify contaminants of emerging concern in riverine and coastal ecosystems and assessment of environmental risks.
Mira Čelić (2020)
Novel cobiomass degradation of NSAIDs by two wood rot fungi, Ganoderma applanatum and Laetiporus sulphureus: Ligninolytic enzymes induction, isotherm and kinetic studies.
P. Bankole (2020)
Optimization of a methodology for simultaneous determination of four antidepressants present in fresh water by high efficiency liquid chromatography
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