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How To Become A Parasite - Lessons From The Genomes Of Nematodes.

C. Dieterich, R. Sommer
Published 2009 · Biology, Medicine

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The phylum Nematoda is biologically diverse; it includes parasites of plants and animals in addition to free-living taxa. To date, the genomes of six nematodes have been sequenced. Comparative analyses of these ecologically diverse nematodes are beginning to reveal the mechanisms by which parasites arise and how they evolve. Here, we discuss some emerging principles for the mechanisms and evolution of parasitism. First, horizontal gene transfer represents a common theme in nematode parasites. Second, the human parasite Brugia malayi lost otherwise essential genes most probably owing to the mutualistic relationship with a bacterial endosymbiont. Finally, some parasitic features evolved under free-living conditions. A recent study revealed a conserved endocrine mechanism controlling the formation of dauer and infective larvae in nematodes.
This paper references
Stage- and Gender-Specific Proteomic Analysis of Brugia malayi Excretory-Secretory Products
Y. Moreno (2008)
A molecular evolutionary framework for the phylum Nematoda
M. Blaxter (1998)
Symbiont genes in host genomes: fragments with a future?
M. Blaxter (2007)
Genome Sequence of Aedes aegypti, a Major Arbovirus Vector
V. Nene (2007)
Molecular barcodes for soil nematode identification
R. Floyd (2002)
Advances in Research on Caenorhabditis elegans: Application to Plant Parasitic Nematodes.
D. Riddle (1990)
Endogenous cellulases in animals: Isolation of b-1,4-endoglucanase genes from two species of plant-parasitic cyst nematodes (endoglucanaseyGloboderayHeteroderayin situ hybridizationysecretory protein)
G. Smant (1998)
Recent developments in marine benthic biodiversity research
P. Lambshead (1993)
The Pristionchus pacificus genome provides a unique perspective on nematode lifestyle and parasitism
C. Dieterich (2008)
Phylum-wide analysis of SSU rDNA reveals deep phylogenetic relationships among nematodes and accelerated evolution toward crown Clades.
M. Holterman (2006)
Phylogeny of the nematode genus Pristionchus and implications for biodiversity, biogeography and the evolution of hermaphroditism
W. Mayer (2007)
MUSCLE: multiple sequence alignment with high accuracy and high throughput.
R. Edgar (2004)
The origins of zooparasitic nematodes
R. C. Anderson (1984)
Die Präadaptation freilebender Nematoden an den Parasitismus
G. Osche (1956)
Direct Identification of the Meloidogyne incognita Secretome Reveals Proteins with Host Cell Reprogramming Potential
Stéphane Bellafiore (2008)
Meiotic Parthenogenesis in a Root-Knot Nematode Results in Rapid Genomic Homozygosity
Q. Liu (2007)
Phylogenetic Relationships of the Wolbachia of Nematodes and Arthropods
Katelyn Fenn (2006)
The Genome Sequence of the Malaria Mosquito Anopheles gambiae
R. Holt (2002)
The Pinewood Nematode Bursaphelenchus xylophilus
M. Mota (2004)
Draft Genome of the Filarial Nematode Parasite Brugia malayi
E. Ghedin (2007)
Genome sequence of the metazoan plant-parasitic nematode Meloidogyne incognita
P. Abad (2008)
Transcriptome analysis of root-knot nematode functions induced in the early stages of parasitism.
G. Dubreuil (2007)
Evolutionary Ecology of Parasites
R. Poulin (1997)
Ecology of Caenorhabditis species.
K. Kiontke (2006)
EMBOSS: the European Molecular Biology Open Software Suite.
P. Rice (2000)
The Wolbachia Genome of Brugia malayi: Endosymbiont Evolution within a Human Pathogenic Nematode
J. Foster (2005)
The secretome of the filarial parasite, Brugia malayi: proteomic profile of adult excretory-secretory products.
J. Hewitson (2008)
A Conserved Endocrine Mechanism Controls the Formation of Dauer and Infective Larvae in Nematodes
Akira Ogawa (2009)
Wolbachia: a bug's life in another bug.
A. Hoerauf (2007)
Nematology: terra incognita no more
J. McCarter (2008)
Pristionchus pacificus: an appropriate fondness for beetles
J. Srinivasan (2008)
Nematodes of the genus Pristionchus are closely associated with scarab beetles and the Colorado potato beetle in Western Europe.
M. Herrmann (2006)
Small subunit ribosomal DNA-based phylogeny of basal Chromadoria (Nematoda) suggests that transitions from marine to terrestrial habitats (and vice versa) require relatively simple adaptations.
M. Holterman (2008)
Pristionchus pacificus: a well-rounded nematode.
R. Hong (2006)
Widespread Lateral Gene Transfer from Intracellular Bacteria to Multicellular Eukaryotes
J. D. Hotopp (2007)
Sequence and genetic map of Meloidogyne hapla: A compact nematode genome for plant parasitism
C. Opperman (2008)
Initial sequencing and analysis of the human genome.
E. Lander (2001)
The Nematode Pristionchus pacificus (Nematoda: Diplogastridae) Is Associated with the Oriental Beetle Exomala orientalis (Coleoptera: Scarabaeidae) in Japan
M. Herrmann (2007)
Caenorhabditis elegans is a nematode.
M. Blaxter (1998)
An introduction to nematodes: general nematology. A students textbook.
B. Weischer (2000)
Genome sequence of Aedes aegypti, a mayor arbovirus
V Nene (2007)

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Discovery of a Functional Ecdysone Response Element in Brugia malayi
Tracy Enright (2011)
A Bayesian method for analyzing lateral gene transfer.
J. Sjöstrand (2014)
Quantitative Assessment of the Nematode Fauna Present on Geotrupes Dung Beetles Reveals Species-Rich Communities with a Heterogeneous Distribution
A. Weller (2010)
Facultative parasites as evolutionary stepping-stones towards parasitic lifestyles
L. Luong (2019)
Trichinella spiralis: Adaptation and parasitism.
D. Zarlenga (2016)
Development of a copro-diagnostic molecular tool for the detection and identification of amphibian infecting helminths
Lucas G Huggins (2016)
Diversity Of Naturally Occurring Nematode Destroying Fungi And Their Interaction With Soil Amendments In Banana Farms In Meru And Embu Counties
J. W. Wangu (2016)
Nuclear genomic signals of the ‘microturbellarian’ roots of platyhelminth evolutionary innovation
C. E. Laumer (2015)
Nematode orphan genes are adopted by conserved regulatory networks and find a home in ecology
Melanie G. Mayer (2015)
Experimental evolution of infectious behaviour in a facultative ectoparasite
E. S. Durkin (2018)
The Many Roads to Parasitism : A Tale of Convergence
S. Hay (2011)
A review of the taxonomy, phylogeny, distribution and co-evolution of Schistonchus Cobb, 1927 with proposal of Ficophagus n. gen. and Martininema n. gen. (Nematoda: Aphelenchoididae)
K. Davies (2015)
Plant-nematode interactions: from genomics to metabolomics.
M. Ali (2015)
What Nematode genomes tell us about the importance of horizontal gene transfers in the evolutionary history of animals
E. Danchin (2011)
Comparative analysis of gene duplications and their impact on expression levels in nematode genomes
P. Baskaran (2017)
Glycoside Hydrolase (GH) 45 and 5 Candidate Cellulases in Aphelenchoides besseyi Isolated from Bird’s-Nest Fern
Guan-Long Wu (2016)
Analyse évolutive et fonctionnelle des Macrophage Migration Inhibitory Factors chez les eucaryotes
C. Michelet (2018)
Analysis of the association between Pristionchus and beetles with emphasis on the special case of P. uniformis
Isabella D'Anna (2011)
Genomic Insights into the Origin of Parasitism in the Emerging Plant Pathogen Bursaphelenchus xylophilus
T. Kikuchi (2011)
Testudinema gilchristi n. gen., n. sp. (Nematoda: Monhysteridae) from the perianal folds of stinkpot turtles, Sternotherus odoratus (Testudines), USA
Eyualem Abebe (2012)
Parallels between plant and animal parasitic nematodes
A. Maule (2011)
Elucidating the molecular and developmental biology of parasitic nematodes: Moving to a multiomics paradigm.
Guangxu Ma (2020)
Molecular taxonomic characterization of the human parasitic population of the nematode Strongyloides stercoralis in Cambodia and development and evaluation of methods for the genetic study of Strongyloides ratti
Eberhard Karls (2016)
The levamisole sensitive nicotinic acetylcholine receptor of the potato cyst nematode Globodera pallida
Jessica Marvin (2015)
Targeting internal processes of plant-parasitic nematodes in the pursuit of novel agents for their control
E. P. Masler (2014)
Horizontal gene transfer of microbial cellulases into nematode genomes is associated with functional assimilation and gene turnover
W. Mayer (2010)
The many roads to parasitism: a tale of convergence.
R. Poulin (2011)
Structural and functional characterisation of the fork head transcription factor-encoding gene, Hc-daf-16, from the parasitic nematode Haemonchus contortus (Strongylida).
M. Hu (2010)
Isolating and Characterizing the C. sp. 34 Dauer Larva
E. Hammerschmith (2017)
Gene expression studies on the evolution of development and innate immunity in the nematode Pristionchus pacificus
A. Sinha (2012)
Die Chemie und der Wurm: Caenorhabditis elegans als Plattform für das Zusammenführen von chemischer und biologischer Forschung
S. E. Hulme (2011)
MicroRNAs of Toxocara canis and their predicted functional roles
Guangxu Ma (2016)
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