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Electrophoretic Deposition Of Hydroxyapatite-iron Oxide-chitosan Composite Coatings On Ti–13Nb–13Zr Alloy For Biomedical Applications

Sandeep Singh, G. Singh, N. Bala
Published 2020 · Materials Science

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Abstract In this study iron oxide (Fe3O4) incorporated hydroxyapatite (HA) and chitosan (CS) composite coatings were developed to enhance the corrosion resistance and surface properties of Ti–13Nb–13Zr alloy. Pure HA and composites with different percentage (1, 3 and 5%, wt%) of Fe3O4 have been fabricated by using the electrophoretic deposition method (EPD). The morphology of the composite coating indicated porous nature with average 10 ± 0.2 µm coating thickness, were examined by scanning electron microscopy (SEM). The wettability behavior and surface roughness values of the composite coatings were measured and discussed. The Electrochemical test was performed to evaluate the corrosion behavior in Ringer's solution. The HA-1wt% Fe3O4 composite coating exhibited the preeminent corrosion resistance with lowest Icorr and the highest Ecorr value as a contrast to HA-3wt% Fe3O4 and HA-5wt% Fe3O4 coatings. Additionally, in vitro bioactivity test were conducted in Ringer's solution for 7 days. It was found that the composite coating enhanced the apatite formation ability, which was further endorsed by SEM-EDX analysis. In conclusion, the composite HA-CS bioactive coating incorporated with Fe3O4 is proposed as a promising candidate for biomedical applications.
This paper references
10.1016/J.PROGPOLYMSCI.2011.02.001
Chitosan—A versatile semi-synthetic polymer in biomedical applications
M. Dash (2011)
10.1016/J.MATLET.2018.09.066
Electrophoretic coatings of hydroxyapatite with various nanocrystal shapes
K. Patel (2019)
10.1016/J.PMATSCI.2006.07.001
A review on fundamentals and applications of electrophoretic deposition (EPD)
L. Besra (2007)
10.1097/00004669-199701000-00009
Biomaterials Science: An Introduction to Materials in Medicine
B. Ratner (1996)
10.1016/J.MATCHEMPHYS.2015.07.040
Corrosion, wettability and thrombogenicity investigation of ion beam modified HAP/Al2O3
D. Shikha (2015)
10.1016/J.BIOMATERIALS.2006.01.017
How useful is SBF in predicting in vivo bone bioactivity?
T. Kokubo (2006)
10.1021/JA064380L
New Benchmark for Water Photooxidation by Nanostructured α-Fe2O3 Films
A. Kay (2006)
10.1039/C5RA21479C
Preparation and characterization of novel Ag doped hydroxyapatite–Fe3O4–chitosan hybrid composites and in vitro biological evaluations for orthopaedic applications
U. Anjaneyulu (2016)
10.1016/J.SURFCOAT.2015.12.086
Electrophoretic deposition of hydroxyapatite coating on Mg–3Zn alloy for orthopaedic application
R. M. Kumar (2016)
10.1515/AMM-2016-0112
Electrophoretic Deposition and Characterisation of Chitosan Coatings on Near-Β Titanium Alloy
D. Jugowiec (2016)
10.1016/J.TSF.2013.09.002
Hydroxyapatite coating on micropore-formed titanium alloy utilizing electrochemical deposition
K. Lee (2013)
10.1016/j.msec.2017.05.023
Electrophoretic deposition of hydroxyapatite-hexagonal boron nitride composite coatings on Ti substrate.
Yapıncak Göncü (2017)
10.1016/J.MSEC.2010.06.019
Crystallization kinetics, mineralization and crack propagation in partially crystallized bioactive glass 45S5
S. Kashyap (2011)
10.1016/j.actbio.2008.02.014
Fabrication and in vitro characterization of magnetic hydroxycarbonate apatite coatings with hierarchically porous structures.
Y. Guo (2008)
10.1016/0022-3093(90)90199-V
Surface chemistry of bioactive glass-ceramics
T. Kokubo (1990)
10.1016/J.JMATPROTEC.2008.04.034
Electrophoretic deposition of bioactive glass/polymer composite coatings with and without HA nanoparticle inclusions for biomedical applications
D. Zhitomirsky (2009)
10.1007/s12540-015-1011-y
Electrophoretic deposition and characterization of HA/chitosan nanocomposite coatings on Ti6Al7Nb alloy
T. Moskalewicz (2015)
10.1016/j.carbpol.2013.12.007
Electrodeposition of alginate/chitosan layer-by-layer composite coatings on titanium substrates.
Z. Wang (2014)
10.1016/j.jascer.2014.10.007
Calcium phosphate-forming ability of magnetite and related materials in a solution mimicking in vivo conditions
Yasuyuki Kato (2015)
10.1007/S00339-018-2240-Y
Fabrication and corrosion property of novel 3-aminopropyltriethoxy-modified calcium phosphate/poly(lactic acid) composite coating on AZ60 Mg alloy
Binxin Li (2018)
10.1016/j.msec.2015.10.073
Structure, apatite inducing ability, and corrosion behavior of chitosan/halloysite nanotube coatings prepared by electrophoretic deposition on titanium substrate.
A. Molaei (2016)
10.1016/J.SURFCOAT.2018.02.030
The study of electrodeposition of hydroxyapatite-ZrO2-TiO2 nanocomposite coatings on 316 stainless steel
Morteza Poorraeisi (2018)
10.1016/J.TSF.2007.12.047
Surface modification of metals by calcium carbonate thin films on a layer-by-layer polyelectrolyte matrix
A. P. Ramos (2008)
10.1016/J.TSF.2013.09.034
Surface characteristics of hydroxyapatite-coated layer prepared on nanotubular Ti-35Ta-xHf alloys by EB-PVD
Y. Jeong (2013)
10.1002/APP.29984
The enhanced mechanical properties of a covalently bound chitosan‐multiwalled carbon nanotube nanocomposite
Xiaodong Cao (2009)
10.1016/j.jcis.2009.07.064
Fabrication of superhydrophobic sol-gel composite films using hydrophobically modified colloidal zinc hydroxide.
R. Lakshmi (2009)
10.1111/J.1551-2916.2012.05195.X
Multiwalled Carbon Nanotubes Reinforced Hydroxyapatite‐Chitosan Composite Coating on Ti Metal: Corrosion and Mechanical Properties
P. C. Rath (2012)
10.1016/J.CERAMINT.2015.03.145
Electrophoretic deposition of biomimetic zinc substituted hydroxyapatite coatings with chitosan and carbon nanotubes on titanium
Zhenyu Zhong (2015)
10.1016/j.msec.2014.03.019
Electrophoretic co-deposition of polyvinyl alcohol (PVA) reinforced alginate-Bioglass® composite coating on stainless steel: mechanical properties and in-vitro bioactivity assessment.
Q. Chen (2014)
10.1016/j.bios.2008.06.032
Iron oxide nanoparticles-chitosan composite based glucose biosensor.
Ajeet Kaushik (2008)
10.1111/JACE.12386
Spark Plasma Sintered HA-Fe3O4-Based Multifunctional Magnetic Biocomposites
I. Bajpai (2013)
10.1016/J.JMATPROTEC.2007.03.043
Chitosan-mediated electrosynthesis of organic–inorganic nanocomposites
I. Zhitomirsky (2007)
10.1007/s10856-009-3712-6
Chitosan reinforced apatite–wollastonite coating by electrophoretic deposition on titanium implants
S. Sharma (2009)
10.1016/J.MATLET.2016.11.078
Preparation and characterization of novel sol-gel derived hydroxyapatite/Fe3O4 composites coatings on Ti-6Al-4V for biomedical applications
U. Anjaneyulu (2017)
10.1016/J.TSF.2010.08.072
Preparation and characterization of bio-functionalized iron oxide nanoparticles for biomedical application
B. Bajaj (2010)
10.1002/jbm.b.31908
Electrophoretic deposition of bioactive silica-calcium phosphate nanocomposite on Ti-6Al-4V orthopedic implant.
Aniket (2011)
10.1016/J.CERAMINT.2017.09.170
Evaluation of the mechanical properties, in vitro biodegradability and cytocompatibility of natural chitosan/hydroxyapatite/nano-Fe3O4 composite
Fatemeh Heidari (2018)
10.1016/J.MATCHEMPHYS.2017.06.064
Porous HA and nanocomposite nc-TiO2/HA coatings to improve the electrochemical corrosion resistance of the Co-28Cr-5Mo alloy
T. Moskalewicz (2017)
10.1016/j.msec.2013.06.010
Electrophoretic bilayer deposition of zirconia and reinforced bioglass system on Ti6Al4V for implant applications: an in vitro investigation.
K. P. Ananth (2013)
10.1002/jbm.b.31948
Cellular proliferation, cellular viability, and biocompatibility of HA-ZnO composites.
Naresh Saha (2012)
10.1016/J.CERAMINT.2013.11.119
Bioactive HA/TiO2 coating on magnesium alloy for biomedical applications
P. Amaravathy (2014)
10.1016/J.TSF.2011.01.011
Nanotubular surface and morphology of Ti-binary and Ti-ternary alloys for biocompatibility
H. Choe (2011)
10.1016/J.TSF.2013.05.130
Silicon-substituted hydroxyapatite coating with Si content on the nanotube-formed Ti-Nb-Zr alloy using electron beam-physical vapor deposition
Y. Jeong (2013)
10.1186/1471-2474-11-188
Stimulation of osteogenic differentiation in human osteoprogenitor cells by pulsed electromagnetic fields: an in vitro study
J. Jansen (2010)
10.1016/J.TSF.2011.04.090
Surface characteristics of hydroxyapatite/titanium composite layer on the Ti-35Ta-xZr surface by RF and DC sputtering
Won-Gi Kim (2011)
10.1016/J.CERAMINT.2011.12.056
Electrophoretic deposition of nanocomposite (HAp + TiO2) on titanium alloy for biomedical applications
L. Mohan (2012)
10.1016/J.CLAY.2016.09.008
Investigation of halloysite nanotube content on electrophoretic deposition (EPD) of chitosan-bioglass-hydroxyapatite-halloysite nanotube nanocomposites films in surface engineering
A. Molaei (2017)
10.1016/j.jeurceramsoc.2013.04.030
AC vs. DC electrophoretic deposition of hydroxyapatite on titanium
V. O. Kollatha (2013)
10.1016/j.carbpol.2012.06.004
Chitosan-hydroxyapatite composites.
L. Pighinelli (2013)
10.1039/C3RA40535D
Electrophoretic deposition of nanostructured-TiO2/chitosan composite coatings on stainless steel
Luis Cordero-Arias (2013)
10.1016/J.MATLET.2017.04.073
Electrophoretic deposition of anisotropic α-Fe2O3/PVP/chitosan nanocomposites for biomedical applications
L. Ramos-Rivera (2017)
10.2147/IJN.S68719
Functionalized magnetic iron oxide/alginate core-shell nanoparticles for targeting hyperthermia
Shih-Hsiang Liao (2015)
10.1016/j.msec.2015.05.034
Electrophoretic deposition of ZnO/alginate and ZnO-bioactive glass/alginate composite coatings for antimicrobial applications.
L. Cordero-Arias (2015)
10.1039/C5RA03073K
Binding of a quaternary ammonium polymer-grafted-chitosan onto a chemically modified wool fabric surface: assessment of mechanical, antibacterial and antifungal properties
M. M. Hassan (2015)
10.1016/J.CERAMINT.2015.07.170
Modification of electrophoretic deposition of chitosan–bioactive glass–hydroxyapatite nanocomposite coatings for orthopedic applications by changing voltage and deposition time
A. Molaei (2015)
10.1016/J.JALLCOM.2015.06.250
Enhancement of bioactivity of pulsed magnetron sputtered TiCxNy with bioactive glass (BAG) incorporated polycaprolactone (PCL) composite scaffold
V. A. Thampi (2015)
10.1016/J.ELECTACTA.2017.02.081
Electrophoretic deposition and characterization of chitosan/bioactive glass composite coatings on Mg alloy substrates
S. Heise (2017)
10.1016/J.CERAMINT.2016.05.178
Electrophoretic deposition of chitosan/Bioglass® and chitosan/Bioglass®/TiO2 composite coatings for bioimplants
S. Clavijo (2016)
10.1016/J.TSF.2015.01.028
Surface morphology of Zn-containing hydroxyapatite (Zn-HA) deposited electrochemically on Ti–xNb alloys
In-Seop Byeon (2015)
10.1007/S10965-010-9470-9
Preparation and characterization of a Bacterial cellulose/Chitosan composite for potential biomedical application
J. Kim (2011)
10.1016/J.APSUSC.2017.01.022
Structural and corrosion characterization of hydroxyapatite/zirconium nitride-coated AZ91 magnesium alloy by ion beam sputtering
S. R. Kiahosseini (2017)
10.1016/J.MATLET.2011.11.025
Development and characterization of MgO/hydroxyapatite composite coating on AZ31 magnesium alloy by plasma electrolytic oxidation coupled with electrophoretic deposition
D. Sreekanth (2012)
10.1016/J.COMPOSITESB.2014.04.034
Mechanical properties of Fe3O4/GO/chitosan composites
M. Yadav (2014)
10.1016/J.MATLET.2014.04.022
Selective binding and magnetic separation of histidine-tagged proteins using Ni2+-decorated Fe3O4/hydroxyapatite composite nanoparticles
Shasha Yao (2014)
The Iron Oxides: Structure, Properties, Reactions, Occurrences and Uses
R. M. Cornell (1996)
10.1016/0142-9612(90)90067-Z
Studies of the solubility of different calcium phosphate ceramic particles in vitro.
C. P. Klein (1990)
10.1002/JBM.A.20075
Osteoblast attachment and mineralized nodule formation on rough and smooth 45S5 bioactive glass monoliths.
J. Gough (2004)
10.1016/J.APSUSC.2013.11.150
Improvement of corrosion resistance and antibacterial effect of NiTi orthopedic materials by chitosan and gold nanoparticles
R. Ahmed (2014)
10.1016/J.PMATSCI.2008.06.004
Ti based biomaterials, the ultimate choice for orthopaedic implants – A review
M. Geetha (2009)
10.1016/j.biomaterials.2016.01.016
Multifunctional coatings to simultaneously promote osseointegration and prevent infection of orthopaedic implants.
J. Raphel (2016)
10.1016/S0142-9612(99)00255-0
Bond strength of plasma-sprayed hydroxyapatite/Ti composite coatings.
X. Zheng (2000)
10.1016/j.actbio.2007.11.005
Novel sphene coatings on Ti-6Al-4V for orthopedic implants using sol-gel method.
C. Wu (2008)
10.1007/s10856-013-4955-9
Characterisation, corrosion resistance and in vitro bioactivity of manganese-doped hydroxyapatite films electrodeposited on titanium
Y. Huang (2013)
10.1016/J.TSF.2005.09.179
Biomimetic synthesis of carbonated hydroxyapatite thin films
Elisa Boanini (2006)
10.1016/S0142-9612(02)00413-1
Characterization of the bone-like apatite precipitated on high velocity oxy-fuel (HVOF) sprayed calcium phosphate deposits.
K. Khor (2003)
10.5618/BIO.2011.V1.N1.1
Medical Application of Calcium Orthophosphate Bioceramics
S. Dorozhkin (2011)
10.1016/j.jmbbm.2013.06.001
Artificial hip joints: The biomaterials challenge.
G. Pezzotti (2014)
10.1016/J.CERAMINT.2014.04.116
Improved bio-physical performance of hydroxyapatite coatings obtained by electrophoretic deposition at dynamic voltage
Armin Tahmasbi Rad (2014)
10.1016/J.PARTIC.2010.07.026
Template-based growth of titanium dioxide nanorods by a particulate sol-electrophoretic deposition process
M. Mohammadi (2011)
10.2147/IJN.S147355
Magnetic hydroxyapatite: a promising multifunctional platform for nanomedicine application
S. Mondal (2017)
10.1002/APP.27116
Mechanical properties and porosity of polylactide for biomedical applications
Hassan Sawalha (2008)
10.1023/A:1012462332440
Sol-gel-derived hydroxyapatite powders and coatings
E. Tkalčec (2001)
10.1016/J.TSF.2014.08.035
Electrochemical behavior of hydroxyapatite/TiN multi-layer coatings on Ti alloys
E. Kim (2014)
10.1017/cbo9781139035545.005
Characterization of biomaterials
A. Bandyopadhyay (2013)
10.1016/J.TSF.2016.07.089
Electrochemically-coated hydroxyapatite films on nanotubular TiNb alloys prepared in solutions containing Ca, P, and Zn ions
In-Seop Byeon (2016)
10.1016/J.MICROC.2016.04.022
Chitosan/hydroxyapatite/Fe 3 O 4 magnetic composite for metal-complex dye AY220 removal: Recyclable metal-promoted Fenton-like degradation
Pan Hou (2016)
10.1016/J.SURFCOAT.2018.03.050
Electrophoretic deposition of chitosan/bioactive glass/silica coatings on stainless steel and WE43 Mg alloy substrates
S. Heise (2018)
10.1016/J.MATCHEMPHYS.2019.04.037
In-vitro assessment of HA-Nb coating on Mg alloy ZK60 for biomedical applications
B. Singh (2019)
10.1007/s10856-015-5634-9
Electrophoretic deposition of graphene oxide reinforced chitosan–hydroxyapatite nanocomposite coatings on Ti substrate
Y. Y. Shi (2016)
10.1109/TNB.2014.2338931
Comparing Nanostructured Hydroxyapatite Coating on AZ91 Alloy Samples via Sol-gel and Electrophoretic Deposition for Biomedical Applications
Ramin Rojaee (2014)
10.1016/J.SURFCOAT.2017.03.067
Electrophoretic deposition and characterization of composite chitosan-based coatings incorporating bioglass and sol-gel glass particles on the Ti-13Nb-13Zr alloy
D. Jugowiec (2017)
10.1098/rsif.2010.0156.focus
Electrophoretic deposition of biomaterials
A. Boccaccini (2010)
10.1016/J.MATLET.2005.08.062
Preparation of three-dimensional nano-magnetite/chitosan rod
Q. Hu (2006)
10.1007/s11051-012-0964-8
Synthesis optimization and characterization of chitosan-coated iron oxide nanoparticles produced for biomedical applications
Gozde Unsoy (2012)
10.1016/J.SURFCOAT.2016.10.077
Comparison of electrochemical behavior of hydroxyapatite coated onto WE43 Mg alloy by electrophoretic and pulsed laser deposition
M. Sankar (2017)
10.1007/S10853-006-0170-0
Bioactive ceramic coatings containing carbon nanotubes on metallic substrates by electrophoretic deposition
I. Singh (2006)



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