Online citations, reference lists, and bibliographies.
← Back to Search

Minimising Oil Droplet Size Using Ultrasonic Emulsification.

T. Leong, T. J. Wooster, S. Kentish, M. Ashokkumar
Published 2009 · Chemistry, Medicine

Cite This
Download PDF
Analyze on Scholarcy
Share
The efficient production of nanoemulsions, with oil droplet sizes of less than 100nm would facilitate the inclusion of oil soluble bio-active agents into a range of water based foods. Small droplet sizes lead to transparent emulsions so that product appearance is not altered by the addition of an oil phase. In this paper, we demonstrate that it is possible to create remarkably small transparent O/W nanoemulsions with average diameters as low as 40nm from sunflower oil. This is achieved using ultrasound or high shear homogenization and a surfactant/co-surfactant/oil system that is well optimised. The minimum droplet size of 40nm, was only obtained when both droplet deformability (surfactant design) and the applied shear (equipment geometry) were optimal. The time required to achieve the minimum droplet size was also clearly affected by the equipment configuration. Results at atmospheric pressure fitted an expected exponential relationship with the total energy density. However, we found that this relationship changes when an overpressure of up to 400kPa is applied to the sonication vessel, leading to more efficient emulsion production. Oil stability is unaffected by the sonication process.
This paper references
10.1002/CEAT.200406111
High‐Pressure Homogenization as a Process for Emulsion Formation
S. Schultz (2004)
10.1016/J.JFOODENG.2007.03.007
Production of sub-micron emulsions by ultrasound and microfluidization techniques
S. Jafari (2007)
10.1016/0927-7757(94)02743-9
The science and applications of emulsions — an overview
J. Israelachvili (1994)
10.1205/cherd06199
The formation of stable W/O, O/W, W/O/w cosmetic emulsions in an ultrasonic field
Barbara Tal-Figiel (2007)
10.1177/003591577106400947
Ultrasound
I. Donald (1971)
L'Alloret, Nanoemulsions: a new vehicle for skincare products, Advances in Colloid and Interface
O. Sonneville-Aubrun (2004)
10.2307/j.ctvrnfqk1.10
? ? ? ? f ? ? ? ? ?
A. ADoefaa (2003)
10.1098/RSPA.1934.0169
The formation of emulsions in definable fields of flow
G. I. Taylor (1934)
Cosmetic nanoemulsions
M. Schifone (2006)
10.1016/J.COCIS.2006.08.003
Polyelectrolyte/surfactant mixtures at the air–solution interface
J. Penfold (2006)
10.1016/0009-2509(93)80021-H
Principles of emulsion formation
P. Walstra (1993)
10.1016/J.CEP.2007.09.014
Cavitational reactors for process intensification of chemical processing applications: A critical review
P. Gogate (2008)
10.1016/0009-2509(93)80164-L
hydrolysis of fatty oils: effect of cavitation
A. B. Pandit (1993)
10.1016/J.JCIS.2006.07.055
Formation and stability of paraffin oil-in-water nano-emulsions prepared by the emulsion inversion point method.
W. Liu (2006)
10.1021/la801685v
Impact of oil type on nanoemulsion formation and Ostwald ripening stability.
T. J. Wooster (2008)
10.1016/j.jcis.2007.03.059
Emulsification in turbulent flow 1. Mean and maximum drop diameters in inertial and viscous regimes.
Nina Vankova (2007)
Influence of hydrostatic pressure and gas content on continuous ultrasound emulsification, Ultrasonics Sonochemistry
O. Behrend (2001)
Kinetically trapped food grade nano-emulsions
J. V. Henry (2008)
10.1016/J.JCIS.2007.03.059
Emulsification in turbulent flow 1. Mean and maximum drop diameters in inertial and viscous regimes.
N. Vankova (2007)
10.1016/0255-2701(94)04005-2
Developments in the continuous mechanical production of oil-in-water macro-emulsions
H. Karbstein (1995)
10.1016/J.JBIOTEC.2008.07.311
Formation and stability of new palm-based nanoemulsions
M. Basri (2008)
Cavitation
F. R. Young (1989)
Nano-emulsions
C. Solans (2005)
10.1016/J.CIS.2003.10.023
Formation and stability of nano-emulsions.
T. Tadros (2004)
10.1016/J.CIS.2003.10.026
Nanoemulsions: a new vehicle for skincare products.
O. Sonneville-Aubrun (2004)
10.1016/J.ULTSONCH.2004.10.004
Continuous contact- and contamination-free ultrasonic emulsification-a useful tool for pharmaceutical development and production.
S. Freitas (2006)
10.1080/10408440601177780
Grey Goo on the Skin? Nanotechnology, Cosmetic and Sunscreen Safety
G. Nohynek (2007)
10.1016/J.IFSET.2007.07.005
The use of ultrasonics for nanoemulsion preparation
S. E. Kentish (2008)
10.1016/S1350-4177(03)00103-2
Some aspects of the design of sonochemical reactors.
P. Gogate (2003)
10.1016/S1350-4177(01)00088-8
Influence of hydrostatic pressure and gas content on continuous ultrasound emulsification.
O. Behrend (2001)
Schnoring, Kontinuierliches Emulgieren mit Rotor/Stator-Maschinen: Einfluss der volumenbezognenen Dispergierleistung und der Verweizeit auft die Emulsionfeinheit
B. Koglin (1981)
10.1081/SMTS-200056102
Formation of Concentrated Nanoemulsions by Extreme Shear
K. Meleson (2004)
10.1081/PDT-100101357
Performance of sonication and microfluidization for liquid-liquid emulsification.
Y. Maa (1999)
Power measurement in sonochemistry, Ultrasonics Sonochemistry
C. F. Ratoarinoro (1995)
Garcia-Celma, Nano- emulsions
C. Solans (2005)
Principles of emulsion formation, in Emulsion
E.S.R. Gopal (1968)
10.1046/J.1365-2621.2001.00459.X
Food Emulsions: Principles, Practice, and Techniques
P. Williams (2001)
10.1021/J100103A027
Sonochemistry and sonoluminescence: effects of external pressure
A. Henglein (1993)
10.1016/1350-4177(94)00010-P
Power measurement in sonochemistry
Ratoarinoro F. Contamine (1995)
10.1205/CHERD06199
The Formation of Stable W/O, O/W, W/O/W Cosmetic Emulsions in an Ultrasonic Field
B. Tal-Figiel (2007)
Cavitation
F. R. Young (1989)
10.1016/J.JCIS.2007.01.097
Emulsification in turbulent flow: 3. Daughter drop-size distribution.
S. Tcholakova (2007)
Cosmetic nanoemulsions, Cosmetic Technology (Milano, Italy
M. Schifone (2006)
10.1016/J.ULTSONCH.2007.08.010
Influence of hydrostatic pressure and sound amplitude on the ultrasound induced dispersion and de-agglomeration of nanoparticles.
C. Sauter (2008)
10.1016/S1350-4177(98)00027-3
Emulsification by ultrasound: drop size distribution and stability.
B. Abismaı̈l (1999)
Food Emulsions: Principles, Practice, and Techniques
D. J. Mcclements (1998)
10.1016/J.ULTSONCH.2007.06.011
Ultrasound emulsification: effect of ultrasonic and physicochemical properties on dispersed phase volume and droplet size.
S. Gaikwad (2008)
10.1002/CITE.330530813
Kontinuierliches Emulgieren mit Rotor/Stator‐Maschinen: Einfluß der volumenbezogenen Dispergierleistung und der Verweilzeit auf die Emulsionsfeinheit
B. Koglin (1981)
10.1039/TF9353100835
On the mechanism of emulsification by ultrasonic waves
C. Bondy (1935)



This paper is referenced by
10.1002/9781118462157.CH11
Properties and applications of multilayer and nanoscale emulsions
Moumita Ray (2015)
10.1016/B978-0-12-804306-6.00009-X
Nanoemulsion-based delivery systems: preparation and application in the food industry
Solmaz Maleki Dizaj (2016)
10.1007/978-3-319-70166-0_3
Nanotechnology in the Food Industry
Arun G. Ingale (2018)
10.1016/j.foodchem.2014.10.117
Modelling and optimising of physicochemical features of walnut-oil beverage emulsions by implementation of response surface methodology: effect of preparation conditions on emulsion stability.
Mina Homayoonfal (2015)
10.1250/AST.36.240
Increasing unsaturated dissolved oxygen concentration in water by fine bubbles induced by ultrasonic vibrations
Hikaru Miura (2015)
10.1016/j.cep.2019.107649
Ultrasound assisted synthesis of water-in-oil nanoemulsions: Parametric optimization using hybrid ANN-GA approach
Hemant Kumar (2019)
10.1016/j.ultsonch.2019.02.009
Investigations in enhancement biodesulfurization of model compounds by ultrasound pre-oxidation.
Zhigang Yi (2019)
10.1016/S1773-2247(12)50061-4
Prospective study for the development of emulsion systems containing natural oil products
F. H. Xavier-Júnior (2012)
10.1016/j.ultsonch.2013.10.021
Ultrasonic emulsification of eucalyptus oil nanoemulsion: antibacterial activity against Staphylococcus aureus and wound healing activity in Wistar rats.
S. Sugumar (2014)
10.1016/j.cis.2012.03.002
Crystals and crystallization in oil-in-water emulsions: implications for emulsion-based delivery systems.
D. J. Mcclements (2012)
10.1016/J.CEP.2018.08.006
Effect of operating pressure on the performance of ultrasound-assisted oxidative desulfurization (UAOD) using a horn type sonicator: Experimental investigation and CFD simulation
B. Khodaei (2018)
10.1016/B978-0-12-416641-7.00009-2
Essential Oil-Based Nanoemulsion Formation by Low- and High-Energy Methods and Their Application in Food Preservation against Food Spoilage Microorganisms
Saranya Sugumar (2016)
10.1016/B978-0-12-804306-6.00012-X
Production, stability and application of micro- and nanoemulsion in food production and the food processing industry
Md. Khaled Saifullah (2016)
10.1080/01932691.2014.921188
Optimal Development of a New Stable Nutraceutical Nanoemulsion Based on the Inclusion Complex of 2-Hydroxypropyl-β-cyclodextrin with Canthaxanthin Accumulated by Dietzia natronolimnaea HS-1 Using Ultrasound-Assisted Emulsification
Seyed Mohammad Taghi Gharibzahedi (2015)
10.1038/s41467-019-12615-6
Advantages of eutectic alloys for creating catalysts in the realm of nanotechnology-enabled metallurgy
Jianbo Tang (2019)
10.1016/J.APT.2019.05.005
Formation of drug-loaded nanoemulsions in stirred media mills
Julia Felicitas Schwendner (2019)
10.1016/J.TIFS.2019.02.030
Micro and nano encapsulation, retention and controlled release of flavor and aroma compounds: A critical review
M. Saifullah (2019)
10.1016/J.JDDST.2018.12.006
Entrapment of drug-sorbate complex in submicron emulsion: A potential approach to improve antimicrobial activity in bacterial corneal infection
Durga Prasad Pandey (2019)
10.1016/J.SUPFLU.2018.11.018
Ultrasound-assisted emulsion of laurel leaves essential oil (Laurus nobilis L.) encapsulated by SFEE
P. C. Reis (2019)
10.1016/j.ultsonch.2016.03.017
Ultrasonic encapsulation - A review.
T. Leong (2017)
10.1017/jfm.2019.654
Droplet-turbulence interactions and quasi-equilibrium dynamics in turbulent emulsions.
S. Mukherjee (2019)
Designing and Characterization of Emulsion-Based Matrices for the Encapsulation of Bioactive Oils using Polysaccharides
L. Kumar (2017)
10.1007/S12393-009-9012-6
Nanoencapsulation: A New Trend in Food Engineering Processing
M. X. Quintanilla-Carvajal (2010)
10.1016/j.ultsonch.2011.05.017
Process optimization and stability of D-limonene-in-water nanoemulsions prepared by ultrasonic emulsification using response surface methodology.
Po-Hsien Li (2012)
10.7567/JJAP.55.07KE07
A piezoelectric polymer cavitation sensor installed in an emulsion generation microchannel device and an evaluation of cavitation state
Takefumi Kanda (2016)
10.1080/10498850.2019.1571552
Effect of β-Glucan Stabilized Virgin Coconut Oil Nanoemulsion on Properties of Croaker Surimi Gel
Asir Gani (2019)
10.1007/S12649-018-0528-Y
Evaluation the Effects of Ultrasonic Parameters on Simultaneously Extraction and Size Reduction of Lycopene from Tomato Processing Waste
Navideh Anarjan (2020)
10.1016/J.CEP.2013.03.013
Using microparticles to enhance micromixing in a high frequency continuous flow sonoreactor
Masoud Rahimi (2013)
10.1117/1.JBO.19.10.106006
Evaluation of transdermal delivery of nanoemulsions in ex vivo porcine skin using two-photon microscopy and confocal laser-scanning microscopy
Sanghoon Choi (2014)
10.1007/s10311-017-0663-x
Encapsulation of bioactive compounds using nanoemulsions
D. H. Lohith Kumar (2017)
10.1002/jsfa.8958
Ultrasound improving the physical stability of oil-in-water emulsions stabilized by almond proteins.
Zhenbao Zhu (2018)
10.1038/s41598-019-43439-5
Stability Mechanism of Two Soybean Protein-Phosphatidylcholine Nanoemulsion Preparation Methods from a Structural Perspective: A Raman Spectroscopy Analysis
Ying Zhu (2019)
See more
Semantic Scholar Logo Some data provided by SemanticScholar