Online citations, reference lists, and bibliographies.
← Back to Search

Activity Of Two Extracts Of Cynanchum Paniculatum Against Ichthyophthirius Multifiliis Theronts And Tomonts.

W. Ji-hong, Wang Yan-li, Liu Yuhua, Zhang Ji-yuan, L. Zehong
Published 2017 · Biology, Medicine

Cite This
Download PDF
Analyze on Scholarcy
The present study aims to evaluate the antiparasitic activity of active components from Cynanchum paniculatum against Ichthyophthirius multifiliis. The antiparasitic activities of two bioassay-guided fractionationated compounds from C. paniculatum identified as Cynatratoside-A and Cynanversicoside C, by comparing spectral data (NMR and ESI-MS) with literature values, were evaluated by in vitro assay. These showed that both could kill theronts of I. multifiliis at a concentration of 10·0 mg L-1, with the median effective concentration (EC50) values of 4·6 mg L-1 and 5·2 mg L-1 for Cynatratoside-A and Cynanversicoside C, respectively. Encysted tomonts were killed at concentrations of 8·0 mg L-1 with both compounds. In vivo experiments demonstrated that fish treated with both compounds at 15·0 mg L-1 carried significantly fewer parasites than controls (P < 0·05). There were no mortalities among treated fish group compared with 75% mortality of untreated fish. Cynatratoside-A and Cynanversicoside C are therefore potential candidate drugs for use against I. multifiliis.
This paper references
Treatment of ichthyophthiriasis after malachite green. I. Concrete tanks at salmonid farms.
P. Rintamäki-Kinnunen (2005)
The anti-protozoal activity of bronopol on the key life-stages of Ichthyophthirius multifiliis Fouquet, 1876 (Ciliophora).
A. Shinn (2012)
Antitumor activity of C-21 steroidal glycosides from Cynanchum auriculatum Royle ex Wight.
Yun-ru Peng (2008)
Structures of steroidal saponins from the tubers of Brodiaea californica and their inhibitory activity on tumor promoter-induced phospholipid metabolism.
Y. Mimaki (1995)
Use of formalin and copper to control ichthyophthiriosis in the Australian freshwater fish silver perch (Bidyanus bidyanus Mitchell)
S. Rowland (2008)
Effect of potassium ferrate(VI) on survival and reproduction of Ichthyophthirius multifiliis tomonts
F. Ling (2011)
Naegleria fowleri: contact-dependent secretion of electrondense granules (EDG).
B. Chávez-Munguía (2014)
Antiparasitic efficacy of dihydrosanguinarine and dihydrochelerythrine from Macleaya microcarpa against Ichthyophthirius multifiliis in richadsin (Squaliobarbus curriculus).
Jia-Yun Yao (2011)
Antiparasitic properties of medicinal plants and other naturally occurring products.
S. Tagboto (2001)
Steroidal glycosides from the root of Cynanchum versicolor
Q. Sheng-xiang (1989)
Chlorophyllin for the control of Ichthyophthirius multifiliis (Fouquet)
S. Wohllebe (2012)
Anti-parasitic activities of specific bacterial extracellular products of Streptomyces griseus SDX-4 against Ichthyophthirius multifiliis
Jia-Yun Yao (2014)
Production of plant secondary metabolites: a historical perspective
F. Bourgaud (2001)
Appetite suppressing pregnane glycosides from the roots of Cynanchum auriculatum.
Shuangzhu Liu (2013)
Efficacy of Potassium Permanganate in Treating Ichthyophthiriasis in Channel Catfish
D. L. Straus (2002)
Antiparasitic efficacy of Gracillin and Zingibernsis newsaponin from Costus speciosus (Koen ex. Retz) Sm. against Ichthyophthirius multifiliis.
W. Zheng (2015)
Ichthyophthirius multifiliis Fouquet and Ichthyophthiriosis in Freshwater Teleosts.
R. A. Matthews (2005)
Effect of tricaine methanesulfonate on survival and reproduction of the fish ectoparasite Ichthyophthirius multifiliis
De-hai Xu (2008)
Effect of twenty Chinese herbal medicines on killing trophonts,cysts and theronts of Ichthyophthirius multifiliis in vitro
Luo Fen (2010)
Cynanauriculoside C–E, three new antidepressant pregnane glycosides from Cynanchum auriculatum
Q. Yang (2011)
Host responses against the fish parasitizing ciliate Ichthyophthirius multifiliis.
K. Buchmann (2001)
Parasites in fisheries and mariculture.
J. Timi (2015)
Isolation of active compounds from methanol extracts of Toddalia asiatica against Ichthyophthirius multifiliis in goldfish (Carassius auratus).
Xiao-Feng Shan (2014)
Prevention of Ichthyophthirius multifiliis infestation in goldfish (Carassius auratus) by potassium ferrate(VI) treatment.
F. Ling (2010)
Antiparasitic effect of cynatratoside-C from Cynanchum atratum against Ichthyophthirius multifiliis on grass carp.
Yao-wu Fu (2014)
Neuroprotective effects of polyhydroxy pregnane glycoside isolated from Wattakaka volubilis (L.f.) Stapf. after middle cerebral artery occlusion and reperfusion in rats
R. Jadhav (2013)
Effect of sanguinarine from the leaves of Macleaya cordata against Ichthyophthirius multifiliis in grass carp (Ctenopharyngodon idella)
Jia-Yun Yao (2010)
Ichthyophthirius multifiliis (Ich) Epizootics in Spawning Sockeye Salmon in British Columbia, Canada
G. Traxler (1998)
Five new C21 steroidal glycosides from Periploca sepium
L. Wang (2011)
Evaluation of an antiparasitic compound extracted from Galla chinensis against fish parasite Ichthyophthirius multifiliis.
Qizhong Zhang (2013)

This paper is referenced by
Semantic Scholar Logo Some data provided by SemanticScholar