Online citations, reference lists, and bibliographies.
← Back to Search

Randomly Ordered Addressable High-density Optical Sensor Arrays.

K. Michael, L. A. Taylor, S. L. Schultz, D. Walt
Published 1998 · Chemistry, Medicine

Cite This
Download PDF
Analyze on Scholarcy
Share
Array-based sensors provide an architecture for multianalyte sensing. In this paper, we report a new approach for array fabrication. Sensors are made by immobilizing different reactive chemistries on the surfaces of microspheres. Sensor arrays are prepared by randomly distributing a mixture of microsphere sensors on an optical substrate containing thousands of micrometer-scale wells. The sensors occupy a different location from array to array; thus the identity of each sensor is ascertained and registered on the detector using encoding schemes, rather than by a predetermined location in the array. The approach thereby shifts the demand from fabrication to signal processing. The availability of commercial image analysis software makes such a shift both cost-effective and time efficient.



This paper is referenced by
10.1039/B107733C
Spatial confinement of avidin domains in microwell arrays.
C. Meek (2001)
10.1385/1-59259-358-5:443
Real-time measurements of phasic changes in extracellular dopamine concentration in freely moving rats by fast-scan cyclic voltammetry.
P. Phillips (2003)
10.1101/GR.2255804
Decoding randomly ordered DNA arrays.
K. Gunderson (2004)
10.1007/4243_2008_056
Fibre-Optic and Nanoparticle-Based Fluorescence Sensing Using Indicator Dyes: Pitfalls, Self- Referencing, Application, and Future Trends
G. Mohr (2008)
10.1007/978-0-387-79251-4
Biomarkers for Psychiatric Disorders
C. Turck (2009)
Microarray-based gene expression analysis in natural and experimental cases of porcine circovirus type 2 infection
L. T. Fernandes (2015)
10.1111/j.1556-4029.2009.01223.x
Detection and Classification of Ignitable Liquid Residues Using a Fluorescence‐Based Vapor‐Sensitive Microsphere Array *
M. Aernecke (2010)
10.2172/793090
Direct capture of products from biotransformations.
J. Hestekin (2002)
10.1007/b136673
Special-purpose modifications and immobilized functional nucleic acids for biomolecular interactions
D. D. Giusto (2005)
10.1385/1-59259-858-7:369
Nanosystems for Biosensing
E. Tamiya (2005)
10.1007/978-1-59745-328-8_15
Microarrays and Blood Diagnostics
J. Petrík (2007)
10.1007/s00216-008-2194-6
Luminescence-based methods for sensing and detection of explosives
Melissa S Meaney (2008)
10.1038/srep26125
Proteome-wide drug screening using mass spectrometric imaging of bead-arrays
Y. Zhou (2016)
Sensor Review for Trace Detection of Explosives
L. Mokalled (2014)
10.4018/978-1-60566-076-9.CH013
Gene Expression Profiling with the BeadArrayTM Platform
W. Wruck (2009)
10.1016/S0294-3506(00)90101-7
Puces à ADN et autres systèmes d'analyse génomique
J. Hinfray (2000)
Microfluidic bead-based methods for DNA analysis
A. Russom (2005)
10.4028/www.scientific.net/MSF.657.208
A Review of Dye Incorporated Conducting Polymers Application as Sensors and in Solar Cells
Mangaka C. Matoetoe (2010)
Investigating the tumour promoting roles of complement membrane attack complex using global gene expression analysis.
Laurence D. Towner (2013)
10.3390/microarrays2020131
Evaluation of Different Normalization and Analysis Procedures for Illumina Gene Expression Microarray Data Involving Small Changes
D. Johnstone (2013)
10.1007/3-540-36459-5_7
Protein arrays and their role in proteomics.
D. Cahill (2003)
10.1016/B978-044451024-2/50027-8
Affinity-Based Biosensors, Microarrays and Proteomics
E. Nice (2004)
10.1201/9781420028287.CH12
Planar Waveguide Biosensors for Point-of-Care Clinical and Molecular Diagnostics
D. A. Christensen (2005)
10.1002/9780470061565.HBB095
Fiber-Optic Array Biosensors
Rahela Gašparac (2008)
Development and validation of an in vitro model to explore mechanisms of skeletal muscle toxicity
W. Dott (2014)
10.1117/12.456951
Optical imaging fiber-based recombinant bacterial biosensor
I. Biran (2002)
10.1098/rsif.2010.0594
Multiplexed protein analysis using encoded antibody-conjugated microbeads
N. Theilacker (2011)
10.1002/(SICI)1522-2683(20000101)21:1<91::AID-ELPS91>3.0.CO;2-Y
Parallel reactions in open chip‐based nanovials with continuous compensation for solvent evaporation
E. Litborn (2000)
A microarray format for multi-parameter blood group serology
J. Robb (2006)
10.1038/72006
Screening unlabeled DNA targets with randomly ordered fiber-optic gene arrays
F. Steemers (2000)
10.1016/S0925-4005(01)00781-X
Pattern recognition analysis of optical sensor array data to detect nitroaromatic compound vapors
Gregory A. Bakken (2001)
10.1557/PROC-726-Q9.2
Dam-1 Molecular Sieve Forms, Fibers and Films
D. Coutinho (2002)
See more
Semantic Scholar Logo Some data provided by SemanticScholar