Online citations, reference lists, and bibliographies.

Branched Amino Acid Based Poly(ester Urea)s With Tunable Thermal And Water Uptake Properties

Jiayi Yu, F. Lin, M. Becker
Published 2015 · Chemistry

Cite This
Download PDF
Analyze on Scholarcy
Share
A series of amino-acid based poly(ester urea)s (PEU) with controlled amounts of branching was synthesized and characterized. The mechanical properties, thermal characteristics and water absorptions varied widely with the extent of branch unit incorporation. Herein, the details of the synthesis of a linear bis(l-phenylalanine)-hexane 1,6-diester monomer, a branch tri-O-benzyl-l-tyrosine-1,1,1-trimethylethane triester monomer and a series of copolymers are described. The extent of branching was varied by adjusting the molar ratio of linear to branched monomer during the interfacial polymerization. The elastic moduli span a range of values (1.0–3.1 GPa) that overlaps with several clinically available degradable polymers. Increasing the amount of branching monomers reduces the molecular entanglement, which results in a decrease in elastic modulus values and an increase in values of elongation at break. The l-phenylalanine-based poly(ester urea)s also exhibited a branch density dependent water uptake ability t...
This paper references
10.1021/ma00035a017
Unique behavior of dendritic macromolecules : intrinsic viscosity of polyether dendrimers
T. Mourey (1992)
10.1002/marc.1994.030150114
New polymer syntheses, 76 Hyperbranched polyesters by polycondensation of silylated 5‐acetoxyisophthalic acid
H. R. Kricheldorf (1994)
10.1002/(SICI)1099-0518(19980930)36:13<2347::AID-POLA22>3.0.CO;2-9
New polymer syntheses XCIII. Hyperbranched homo- and copolyesters derived from gallic acid and ?-(4-hydroxyphenyl)-propionic acid
H. Kricheldorf (1998)
10.1021/BC034095G
Polyplexes assembled with internally quaternized PAMAM-OH dendrimer and plasmid DNA have a neutral surface and gene delivery potency.
Jung Ryun Lee (2003)
10.1021/BC010103M
Polyester dendritic systems for drug delivery applications: in vitro and in vivo evaluation.
O. L. Padilla De Jesús (2002)
10.1039/C2RA22210H
Hyperbranched polymers for bioimaging
Qi Zhu (2013)
10.1016/S0079-6700(97)00025-7
Dendrimers—Branching out from curiosities into new technologies
Owen A. Matthews (1998)
10.1016/J.PROGPOLYMSCI.2003.12.002
Hyperbranched polymers: from synthesis to applications
C. Gao (2004)
10.1039/c1cs15242d
Multifunctional dendritic polymers in nanomedicine: opportunities and challenges.
J. Khandare (2012)
10.1021/ja01131a008
Molecular Size Distribution in Three Dimensional Polymers. VI. Branched Polymers Containing A—R—Bf-1 Type Units
P. J. Flory (1952)
10.1021/BM049563J
PAMAM-PEG-PAMAM: novel triblock copolymer as a biocompatible and efficient gene delivery carrier.
T. Kim (2004)
10.1021/nn204431m
Noradrenaline-functionalized hyperbranched fluoropolymer-poly(ethylene glycol) cross-linked networks as dual-mode, anti-biofouling coatings.
Philip M. Imbesi (2012)
10.1021/la900323n
Nanoscale cellulose films with different crystallinities and mesostructures--their surface properties and interaction with water.
C. Aulin (2009)
10.1002/POLA.10968
Amphiphilic and hydrophobic surface patterns generated from hyperbranched fluoropolymer/linear polymer networks: Minimally adhesive coatings via the crosslinking of hyperbranched fluoropolymers
D. Gan (2003)
10.1021/MA300955H
How Melt-Stretching Affects Mechanical Behavior of Polymer Glasses
Gregory D. Zartman (2012)
10.1016/j.biomaterials.2010.01.027
Synthesis, characterization and biodegradation of functionalized amino acid-based poly(ester amide)s.
X. Pang (2010)
10.1016/S0142-9612(00)00091-0
Preparation and mechanical properties of polylactic acid composites containing hydroxyapatite fibers.
T. Kasuga (2001)
10.1002/1099-0518(20000715)38:14<2505::AID-POLA10>3.0.CO;2-8
New developments in hyperbranched polymers
B. Voit (2000)
10.1021/bc700390r
Unnatural amino acid incorporation into virus-like particles.
Erica Strable (2008)
10.1002/app.1979.070230212
Biodegradable polymers: Chymotrypsin degradation of a low molecular weight poly(ester‐urea) containing phenylalanine
S. Huang (1979)
10.1002/POLA.20466
Hyperbranched fluoropolymer and linear poly(ethylene glycol) based amphiphilic crosslinked networks as efficient antifouling coatings: An insight into the surface compositions, topographies, and morphologies
C. Gudipati (2004)
10.1021/MA049232Z
Facile Syntheses and Characterization of Hyperbranched Poly(ester−amide)s from Commercially Available Aliphatic Carboxylic Anhydride and Multihydroxyl Primary Amine
X. Li (2004)
10.1002/(SICI)1521-3927(19990801)20:8<453::AID-MARC453>3.0.CO;2-B
Synthesis of hyperbranched aliphatic polyethers via cationic ring-opening polymerization of 3-ethyl-3-(hydroxymethyl)oxetane
Heléne Magnusson (1999)
10.1002/(SICI)1097-4636(19980905)41:3<443::AID-JBM14>3.0.CO;2-J
Comparative histological evaluation of new tyrosine-derived polymers and poly (L-lactic acid) as a function of polymer degradation.
K. A. Hooper (1998)
10.1002/MACP.1997.021980620
Amino acid based bioanalogous polymers. Novel regular poly(ester urethane)s and poly(ester urea)s based on bis(L-phenylalanine) α,ω-alkylene diesters
T. Kartvelishvili (1997)
10.1021/MA401752B
Phenylalanine-Based Poly(ester urea): Synthesis, Characterization, and in vitro Degradation
Jiayi Yu (2014)
10.1016/S0032-3861(98)00846-5
In vitro study of poly(lactic acid) pin degradation
E. Duek (1999)
10.1016/j.actbio.2012.08.035
Resorbable, amino acid-based poly(ester urea)s crosslinked with osteogenic growth peptide with enhanced mechanical properties and bioactivity.
K. D. Stakleff (2013)
10.1002/POLA.24149
Synthesis, characterization, and aqueous self‐assembly of amphiphilic poly(ethylene oxide)‐functionalized hyperbranched fluoropolymers
Wenjun Du (2010)
10.1016/S0300-9440(00)00122-3
Novel hyperbranched resins for coating applications
R. Benthem (2000)
10.1016/j.biomaterials.2010.03.068
The in vitro biocompatibility of self-assembled hyperbranched copolyphosphate nanocarriers.
J. Liu (2010)
10.1016/S0079-6700(00)00011-3
Functional dendrimers, hyperbranched and star polymers
K. Inoue (2000)
10.1016/j.biomaterials.2009.10.021
Self-assembly of phospholipid-analogous hyperbranched polymers nanomicelles for drug delivery.
J. Liu (2010)
10.1021/cr900068q
Hyperbranched and highly branched polymer architectures--synthetic strategies and major characterization aspects.
B. Voit (2009)
10.1021/MA990090W
Controlled Synthesis of Hyperbranched Polyglycerols by Ring-Opening Multibranching Polymerization
A. Sunder (1999)
10.1021/acs.biomac.5b00153
OGP functionalized phenylalanine-based poly(ester urea) for enhancing osteoinductive potential of human mesenchymal stem cells.
Gina M. Policastro (2015)
10.1021/MA401964E
Postelectrospinning “Click” Modification of Degradable Amino Acid-Based Poly(ester urea) Nanofibers
Fei Lin (2013)
10.1016/S0032-3861(97)00892-6
New polymer syntheses 85. Telechelic, star-shaped and hyperbranched polyesters of β-(4-hydroxyphenyl) propionic acid
H. Kricheldorf (1997)
10.1021/MA001267L
Synthesis and Characterization of Bis(2-hydroxypropyl)amide-Based Hyperbranched Polyesteramides
R. Benthem (2001)
10.1002/(SICI)1521-3935(19990701)200:7<1784::AID-MACP1784>3.0.CO;2-B
New polymer syntheses, 101. Liquid-crystalline hyperbranched and potentially biodegradable polyesters based on phloretic acid and gallic acid
A. Reina (1999)
10.1002/(SICI)1521-3927(19990701)20:7<369::AID-MARC369>3.0.CO;2-S
Branched polyether with multiple primary hydroxyl groups: polymerization of 3‐ethyl‐3‐hydroxymethyloxetane
M. Bednarek (1999)
10.1021/JA9632062
Solid-supported hyperbranched polymerization: Evidence for self-limited growth
P. Bharathi (1997)
10.1021/ja00038a093
Lyotropic liquid crystalline hyperbranched aromatic polyamides
Y. Kim (1992)
10.1002/(SICI)1099-0518(199808)36:11<1685::AID-POLA1>3.0.CO;2-R
Hyperbranched polymers 10 years after
Y. Kim (1998)
10.1126/science.269.5227.1080
Self-Condensing Vinyl Polymerization: An Approach to Dendritic Materials
Jean M. J. Fr�chet (1995)
10.1016/J.POLYMER.2005.12.007
Synthesis and characterization of biodegradable non-toxic poly(ester-urethane-urea)s based on poly(ε-caprolactone) and amino acid derivatives
Á. Marcos-Fernández (2006)
10.1021/ja00011a031
Hyperbranched macromolecules via a novel double-stage convergent growth approach
K. L. Wooley (1991)
10.1002/POLA.10301
Discovery of dendrimers and dendritic polymers: A brief historical perspective*
D. Tomalia (2002)
10.1126/science.8134834
Functional polymers and dendrimers: reactivity, molecular architecture, and interfacial energy.
Jean M. Frechet (1994)
10.1021/ma900798h
Synthesis of Hyperbranched Polyphosphates by Self-Condensing Ring-Opening Polymerization of HEEP without Catalyst
Jinyao Liu (2009)
10.1021/MA060807X
Comparison of the Thermotropic and Solution Behavior of Six-Arm Star and Comb Poly [11-(4'-cyanophenyl-4''-phenoxy) undecyl acrylate] s
A. Kasko (2006)
10.1002/adma.201000369
Self-assembly of hyperbranched polymers and its biomedical applications.
Y. Zhou (2010)
10.1039/b711745k
New methodologies in the construction of dendritic materials.
A. Carlmark (2009)
10.1021/MA100416P
Synthesis of Hyperbranched Polyacrylates by a Chloroinimer Approach
C. Pugh (2010)
10.1021/bm800595b
Amphiphilic hyperbranched fluoropolymers as nanoscopic 19F magnetic resonance imaging agent assemblies.
Wenjun Du (2008)
10.1016/J.BIOMATERIALS.2003.09.110
The formation of poly(ester-urea) networks in the absence of isocyanate monomers.
J. Zimmermann (2004)
10.1021/BM034239U
Nanogel formation consisting of DNA and poly(amido amine) dendrimer studied by static light scattering and atomic force microscopy.
A. Mitra (2004)
10.1039/b814560c
Supramolecular self-assembly of amphiphilic hyperbranched polymers at all scales and dimensions: progress, characteristics and perspectives.
Y. Zhou (2009)
10.1021/MA951909I
Hyperbranched poly(ethylene glycol)s: A new class of ion-conducting materials
C. Hawker (1996)



This paper is referenced by
Semantic Scholar Logo Some data provided by SemanticScholar