Online citations, reference lists, and bibliographies.
← Back to Search

Magnetic Switch Of Permeability For Polyelectrolyte Microcapsules Embedded With Co@Au Nanoparticles.

Z. Lu, Malcolm Prouty, Zhanhu Guo, V. Golub, C. Kumar, Y. Lvov
Published 2005 · Materials Science, Medicine

Save to my Library
Download PDF
Analyze on Scholarcy
We explored using a magnetic field to modulate the permeability of polyelectrolyte microcapsules prepared by layer-by-layer self-assembly. Ferromagnetic gold-coated cobalt (Co@Au) nanoparticles (3 nm diameter) were embedded inside the capsule walls. The final 5 mum diameter microcapsules had wall structures consisting of 4 bilayers of poly(sodium styrene sulfonate)/poly(allylamine hydrochloride) (PSS/PAH), 1 layer of Co@Au, and 5 bilayers of PSS/PAH. External alternating magnetic fields of 100-300 Hz and 1200 Oe were applied to rotate the embedded Co@Au nanoparticles, which subsequently disturbed and distorted the capsule wall and drastically increased its permeability to macromolecules like FITC-labeled dextran. The capsule permeability change was estimated by taking the capsule interior and exterior fluorescent intensity ratio using confocal laser scanning microscopy. Capsules with 1 layer of Co@Au nanoparticles and 10 polyelectrolyte bilayers are optimal for magnetically controlling permeability. A theoretical explanation was proposed for the permeability control mechanisms. "Switching on" of these microcapsules using a magnetic field makes this method a good candidate for controlled drug delivery in biomedical applications.
This paper references

This paper is referenced by
Shell-in-shell microcapsules: a novel tool for integrated, spatially confined enzymatic reactions.
O. Kreft (2007)
Progress in the preparation of magnetic nanoparticles for applications in biomedicine
A. G. Roca (2009)
Responsive microcapsule reactors based on hydrogen-bonded tannic acid layer-by-layer assemblies
V. Kozlovskaya (2010)
Stimuli-responsive nanoparticles, nanogels and capsules for integrated multifunctional intelligent systems
M. Motornov (2010)
Synthesis of hollow magnetic and luminescent bifunctional composite nanoparticles
J. Zhu (2016)
Near-infrared electrochromism of multilayer films of a cyclometalated diruthenium complex prepared by layer-by-layer deposition on metal oxide substrates
Zhijuan Li (2019)
Capsules with external navigation and triggered release.
D. Shchukin (2014)
Author ' s personal copy Polymeric multilayer capsules delivering biotherapeutics ☆
L. D. Cock (2011)
Synthesis and properties of poly(d,l-lactide) drug carrier with maghemite nanoparticles
H. Yin (2010)
Functional multilayered capsules for targeting and local drug delivery
M. Matsusaki (2009)
Assembling polyelectrolytes and porphyrins into hollow capsules with laser-responsive oxidative properties
Matthieu F. Bédard (2009)
A Mini-Review of Magnetic Nanoparticles: Applications in Biomedicine
T. Zare (2015)
Size control of poly(D,L-lactide-co-glycolide) and poly (D,L -lactide -co -glycolide ) -magnetite nanoparticles synthesized by emulsion evaporation technique
C. Astete (2007)
Silver nanoparticles modified nanocapsules for ultrasonically activated drug delivery
S. Anandhakumar (2012)
Magnetically triggered release of molecular cargo from iron oxide nanoparticle loaded microcapsules.
S. Carregal-Romero (2015)
Heat-driven size reduction of biodegradable polyelectrolyte multilayer hollow capsules assembled on CaCO3 template.
D. Trushina (2018)
Polyelectrolyte microcapsules for biomedical applications
B. G. D. Geest (2009)
Synthesis, properties and perspectives of hybrid nanocrystal structures.
P. Cozzoli (2006)
Multifunctional polyelectrolyte microcapsules as a contrast agent for photoacoustic imaging in blood.
A. Yashchenok (2016)
Epitaxial electrodeposition of cobalt on a Pt(111) electrode covered with a Cu(111) film
Po Yu Yen (2011)
Osteogenic effects of inductive coupling magnetism from magnetic 3D printed hydrogel scaffold
H. Lin (2020)
Folate-decorated succinylchitosan nanoparticles conjugated with doxorubicin for targeted drug delivery.
S. Sahu (2011)
Biomedical nanoparticle carriers with combined thermal and magnetic responses
Ting-Yu Liu (2009)
Micropackaging via layer-by-layer assembly: microcapsules and microchamber arrays
M. Antipina (2014)
Multifunctional composite core-shell nanoparticles.
S. Wei (2011)
Layer-by-Layer Self-Assembly of Polyelectrolytes on Superparamagnetic Nanoparticle Surfaces
Zied Ferjaoui (2020)
Polymeric nanomaterials – synthesis, functionalization and applications in diagnosis and therapy
J. Rieger (2007)
Release mechanisms for polyelectrolyte capsules.
B. D. De Geest (2007)
Polyelectrolyte Complexes Drug Delivery Technology
L. Srinivas (2015)
Potential use of smart coatings for corrosion protection of metals and alloys: A review
A. A. Nazeer (2018)
Hard and soft nanocomposites enabled by rationally designed nonlinear copolymers derived from high functionality polyols
James Iocozzia (2018)
Looped carbon capturing and environmental remediation: case study of magnetic polypropylene nanocomposites
J. Zhu (2012)
See more
Semantic Scholar Logo Some data provided by SemanticScholar