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Rapid Gel Formation And Adhesion In Photocurable And Biodegradable Block Copolymers With High DOPA Content

B. P. Lee, Chi-Yang Chao, F. N. Nunalee, Emre Motan, K. Shull, P. Messersmith
Published 2006 · Chemistry

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Marine mussels anchor to a variety of surfaces in turbulent intertidal zones through the use of adhesive plaques formed from hardened mussel adhesive proteins (MAPs). It is believed that 3,4-dihydroxyphenylalanine (DOPA) imparts both water-resistant adhesive characteristics and rapid curing ability to MAPs. In this paper, DOPA-modified triblock copolymers were synthesized and used to form adhesive hydrogels. Amphiphilic block copolymers with DOPA content as high as 10 wt % were prepared, and aqueous solutions of the polymers rapidly (<1 min) formed hydrogels by photopolymerization of methacrylate end groups attached to the hydrophobic segments. Contact mechanics adhesion tests were performed on the photocured hydrogels, and it was shown that incorporating DOPA into the polymer structure significantly enhanced work of adhesion to titanium surfaces submerged in an aqueous medium. Work of adhesion values as high as 410 mJ/m2 were recorded for polymers containing 10 wt % DOPA, although the introduction of Lys...
This paper references
SAR QSAR EnViron. Res
S Fujisawa (2002)
J. Macromolecules Macromolecules
G Floudas (1995)
SAR QSAR En V iron
S. Fujisawa (2002)
Polym. Mater. Sci. Eng
J L Dalsin (2004)
EnViron. Sci. Technol
S Martin (1996)
W D Fuller (1976)
Surf. Interface Anal
G Janchen (1999)
J. Am. Chem. Soc
M Yu (1999)
Geremia, E. Cell Biochem. Funct
G Sichel (1987)
J. Adhes. Sci. Technol
M Yu (1987)
Arch. Biochem. Biophys
L M Rzepecki (1991)
J. Appl. Polym. Sci
H Tatehata (2000)
J. Adhes. Sci. Technol
H Tatehata (2001)
J Rodriguez-Hernandez (2003)
R. Misra (2008)
M Deruelle (1995)
Int. J. Adhes. Adhes. Biotechnol. Genet. Eng. ReV. J. Biol. Chem
J H Waite (1987)
Int. J. Biol. Macromol
H Yamamoto (1990)
Integr. Comp. Biol
J H Waite (2002)
K Huang (2002)
J. Am. Chem. Soc
B.-H Hu (2003)
J. Colloid Interface Sci
H Yamamoto (1993)
J. Org. Chem. Proc. R. Soc
N N Reed (1971)
J. Am. Chem. Soc
J L Dalsin (2003)
Macromol. Chem. Phys
E Andrzejewska (1998)
L Nakonieczna (1055)
J. Polym. Sci., Part A: Polym. Chem
H.-A Klok (2001)
J. Phys. Chem. B
G L Kenausis (2000)
En V iron
P. Z. Araujo (1996)
J. Polym. Sci., Part A: Polym. Chem
J A Burdick (2001)
C M Flanigan (1999)
Org. Lett
R W Flood (2001)
MA0518959 1748 Lee et al. Macromolecules
J H Waite (1990)
R A Stile (2003)
J. Ind. Eng. Chem. Res
I V Khudyakov (1999)
F. G. Young (1955)
Am. Surg
W R Ranger (1997)
J. Biomater. Sci., Polym. Ed
B P Lee (2004)
J. Am. Chem. Soc
A R Statz (2005)
J. Appl. Polym. Sci
M Dossot (2000)
J. Colloid Interface Sci
H Yamamoto (1995)
Interface Sci
H J Hertz (1881)
S R Sousa (2004)
B P Lee (2002)
57) Sugumaran, M. AdV. Insect Physiol

This paper is referenced by
Thermal gelation and tissue adhesion of biomimetic hydrogels.
Seán Burke (2007)
Autodesk and Stereolithography 3D Printing: Bio-inspired Resins for Better Human and Environmental Health
C. cheng (2015)
Ionically Crosslinked Polymer Networks for Underwater Adhesion and Long-Term Controlled Release
Patrick G. Lawrence (2014)
Versatile anti-fouling surface design through nature-inspired approaches
Yuji Higaki (2017)
Integrating Mussel Chemistry into a Bio-Based Polymer to Create Degradable Adhesives
Courtney L Jenkins (2017)
A novel low-friction surface for biomedical applications: modification of poly(dimethylsiloxane) (PDMS) with polyethylene glycol(PEG)-DOPA-lysine.
K. Chawla (2009)
Mussel-inspired bioadhesives in healthcare: design parameters, current trends, and future perspectives.
Nikhil Pandey (2020)
pH Responsive and Oxidation Resistant Wet Adhesive based on Reversible Catechol–Boronate Complexation
Ameya R Narkar (2016)
Molecular weight effects upon the adhesive bonding of a mussel mimetic polymer.
Courtney L Jenkins (2013)
Preparation and characterization of a photocrosslinkable bioadhesive inspired by marine mussel.
Jie Xue (2013)
Substrate independent coating formation and anti-biofouling performance improvement of mussel inspired polydopamine.
Yuan Dang (2015)
Surface modification of PE porous membranes based on the strong adhesion of polydopamine and covalent immobilization of heparin
Jinhong Jiang (2010)
Protein- and Metal-dependent Interactions of a Prominent Protein in Mussel Adhesive Plaques*
D. Hwang (2010)
Catechol‐Based Biomimetic Functional Materials and their Applications
F. Busqué (2014)
Proposal of a new method for treating type II odontoid fractures: Odontoid process prosthetic (Ti)
M. Johnston (2008)
Controlled RAFT Polymerization and Zinc Binding Performance of Catechol-Inspired Homopolymers
A. Isakova (2014)
Freeze-drying synthesis, characterization and in vitro bioactivity of chitosan/graphene oxide/hydroxyapatite nanocomposite
F. Mohandes (2014)
Catechol-functionalized hydrogels: biomimetic design, adhesion mechanism, and biomedical applications.
W. Zhang (2020)
Novel wound sealants: biomaterials and applications
H. Peng (2010)
Bioinspired catecholic chemistry for surface modification.
Q. Ye (2011)
Self-assembly of alkylcatechols on HOPG investigated by scanning tunneling microscopy and molecular dynamics simulations
J. Saiz-Poseu (2012)
Simultaneous Reduction and Surface Functionalization of Graphene Oxide for Hydroxyapatite Mineralization
H. Liu (2012)
Mussel-Inspired Thiol–Ene Polymer Networks: Influencing Network Properties and Adhesion with Catechol Functionality
B. Sparks (2012)
Mussel‐Inspired Polyesters with Aliphatic Pendant Groups Demonstrate the Importance of Hydrophobicity in Underwater Adhesion
Y. Xu (2017)
A new microporous layer material to improve the performance and durability of polymer electrolyte membrane fuel cells
Y. Jiang (2015)
Preparation and characterization of a bioadhesive with poly (vinyl alcohol) crosslinking agent
J. Xue (2013)
Quinone-rich polydopamine functionalization of yttria stabilized zirconia for apatite biomineralization: The effects of coating temperature
Norhidayu Muhamad Zain (2015)
Biomimetic Adhesives and Coatings Based on Mussel Adhesive Proteins
Yuan Liu (2016)
Bioinspired Functional Catechol Derivatives Through Simple Thiol Conjugate Addition.
J. Mancebo-Aracil (2019)
Versatile nanostructured materials via direct reaction of functionalized catechols.
J. Saiz-Poseu (2013)
Cell-instructive pectin hydrogels crosslinked via thiol-norbornene photo-click chemistry for skin tissue engineering.
Rúben F. Pereira (2018)
Ionically cross-linked poly(allylamine) as a stimulus-responsive underwater adhesive: ionic strength and pH effects.
P. G. Lawrence (2015)
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