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Controlling Hydrogel Mechanics Via Bio-Inspired Polymer-Nanoparticle Bond Dynamics.

Q. Li, D. Barrett, P. Messersmith, N. Holten-Andersen
Published 2016 · Materials Science, Medicine

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Interactions between polymer molecules and inorganic nanoparticles can play a dominant role in nanocomposite material mechanics, yet control of such interfacial interaction dynamics remains a significant challenge particularly in water. This study presents insights on how to engineer hydrogel material mechanics via nanoparticle interface-controlled cross-link dynamics. Inspired by the adhesive chemistry in mussel threads, we have incorporated iron oxide nanoparticles (Fe3O4 NPs) into a catechol-modified polymer network to obtain hydrogels cross-linked via reversible metal-coordination bonds at Fe3O4 NP surfaces. Unique material mechanics result from the supra-molecular cross-link structure dynamics in the gels; in contrast to the previously reported fluid-like dynamics of transient catechol-Fe(3+) cross-links, the catechol-Fe3O4 NP structures provide solid-like yet reversible hydrogel mechanics. The structurally controlled hierarchical mechanics presented here suggest how to develop hydrogels with remote-controlled self-healing dynamics.
This paper references
10.1039/c3cc48896a
Multi-stimuli responsive self-healing metallo-hydrogels: tuning of the gel recovery property.
Shibaji Basak (2014)
10.1021/ja5097094
Self-healing multiphase polymers via dynamic metal-ligand interactions.
Davoud Mozhdehi (2014)
10.3390/ma3052986
Development of Biomedical Polymer-Silicate Nanocomposites: A Materials Science Perspective
C. Wu (2010)
10.1021/BM025546N
Synthesis and gelation of DOPA-modified poly(ethylene glycol) hydrogels.
B. P. Lee (2002)
10.1074/JBC.270.34.20183
Hydroxyarginine-containing Polyphenolic Proteins in the Adhesive Plaques of the Marine Mussel Mytilus edulis(*)
V. Papov (1995)
10.1016/j.biomaterials.2010.02.073
A pH-sensitive molecularly imprinted nanospheres/hydrogel composite as a coating for implantable biosensors.
Chunyan Wang (2010)
10.1021/MA047431C
Mechanism of Forming Organic/Inorganic Network Structures during In-situ Free-Radical Polymerization in PNIPA−Clay Nanocomposite Hydrogels
K. Haraguchi (2005)
10.1126/SCIENCE.212.4498.1038
Polyphenolic Substance of Mytilus edulis: Novel Adhesive Containing L-Dopa and Hydroxyproline.
J. Waite (1981)
10.1021/LA062042S
Colloidal stabilization of nanoparticles in concentrated suspensions.
A. Studart (2007)
10.1021/nn203735b
Multidentate catechol-based polyethylene glycol oligomers provide enhanced stability and biocompatibility to iron oxide nanoparticles.
Hyon Bin Na (2012)
Self - Healing MusselInspired MultipHResponsive Hydrogels
M. Krogsgaard
10.1002/ADFM.201202034
Reinforcement of Shear Thinning Protein Hydrogels by Responsive Block Copolymer Self-Assembly.
M. Glassman (2013)
10.1039/c2nr31276j
Pebbles and PebbleJuggler: software for accurate, unbiased, and fast measurement and analysis of nanoparticle morphology from transmission electron microscopy (TEM) micrographs.
S. Mondini (2012)
10.1039/c2cc34745h
A magnetic self-healing hydrogel.
Yaling Zhang (2012)
10.1126/SCIENCE.1147241
Mussel-Inspired Surface Chemistry for Multifunctional Coatings
H. Lee (2007)
10.1021/MA9709011
Synthesis and Linear Viscoelasticity of Fluorinated Hydrophobically Modified Ethoxylated Urethanes (F-HEUR)
Nathalie Cathébras (1998)
10.1021/nl902212q
Ultrastable iron oxide nanoparticle colloidal suspensions using dispersants with catechol-derived anchor groups.
E. Amstad (2009)
10.1038/nature05968
A reversible wet/dry adhesive inspired by mussels and geckos
H. Lee (2007)
10.1002/marc.201100248
Self-healing in nanocomposite hydrogels.
K. Haraguchi (2011)
10.1021/la401858s
Catechol-functionalized chitosan/iron oxide nanoparticle composite inspired by mussel thread coating and squid beak interfacial chemistry.
O. Zvarec (2013)
10.1002/adma.201301034
Clay: new opportunities for tissue regeneration and biomaterial design.
J. Dawson (2013)
10.1126/science.1130557
Nanoparticle Polymer Composites: Where Two Small Worlds Meet
A. C. Balazs (2006)
10.1021/BI002718X
Polyphosphoprotein from the adhesive pads of Mytilus edulis.
J. Waite (2001)
10.1002/1521-4095(200109)13:17<1320::AID-ADMA1320>3.0.CO;2-8
Gold Nanoparticle/Hydrogel Composites with Solvent‐Switchable Electronic Properties
V. Pardo-Yissar (2001)
10.1002/adhm.201200316
Mechanically robust, negative-swelling, mussel-inspired tissue adhesives.
D. Barrett (2013)
10.1039/C3SM51824H
Versatile tuning of supramolecular hydrogels through metal complexation of oxidation-resistant catechol-inspired ligands.
M. Menyo (2013)
10.1039/P29950000259
Spontaneous autoxidation of dopamine
E. Herlinger (1995)
10.1038/nature08693
High-water-content mouldable hydrogels by mixing clay and a dendritic molecular binder
Q. Wang (2010)
10.1002/1521-4095(20020816)14:16<1120::AID-ADMA1120>3.0.CO;2-9
Nanocomposite Hydrogels: A Unique Organic–Inorganic Network Structure with Extraordinary Mechanical, Optical, and Swelling/De‐swelling Properties
K. Haraguchi (2002)
10.1103/PHYSREVLETT.53.958
Models of hierarchically constrained dynamics for glassy relaxation
R. G. Palmer (1984)
10.1007/S00396-008-1949-0
Nanocomposite polymer hydrogels
Patrick J. Schexnailder (2009)
10.1021/bm301908y
Adhesion of mussel foot protein-3 to TiO2 surfaces: the effect of pH.
J. Yu (2013)
Bio-mimetic metal-ligand crosslinks yield self-healing polymer networks with near-covalent elastic moduli
Niels Holten-Andersen (2011)
10.1002/POLA.23607
HYDROGELS FROM SOFT CONTACT LENSES AND IMPLANTS TO SELF-ASSEMBLED NANOMATERIALS.
J. Kopeček (2009)
10.1039/C3TB21374A
Metal-coordination: Using one of nature's tricks to control soft material mechanics.
Niels Holten-Andersen (2014)
10.1073/pnas.1015862108
pH-induced metal-ligand cross-links inspired by mussel yield self-healing polymer networks with near-covalent elastic moduli
Niels Holten-Andersen (2011)
10.1021/bm301844u
Self-healing mussel-inspired multi-pH-responsive hydrogels.
M. Krogsgaard (2013)
10.1039/c2cc31996a
Mussel-inspired load bearing metal-polymer glues.
A. Stepuk (2012)
10.1039/C2JM32439C
Mussel foot protein-1 (mcfp-1) interaction with titania surfaces().
D. Hwang (2012)
10.1126/science.1181044
Iron-Clad Fibers: A Metal-Based Biological Strategy for Hard Flexible Coatings
Matthew J. Harrington (2010)
10.1021/CM050060+
Magnetite Nanocrystals: Nonaqueous Synthesis, Characterization, and Solubility†
N. Pinna (2005)
10.1126/science.1188328
Hydrogen Bonding Controls the Dynamics of Catechol Adsorbed on a TiO2(110) Surface
S. Li (2010)
10.1073/pnas.0605552103
Single-molecule mechanics of mussel adhesion
H. Lee (2006)



This paper is referenced by
10.1016/j.polymer.2020.122214
Bioinspired functional organohydrogels with synergistic multiphases heterostructure
J. Huang (2020)
10.1039/d0sm01776k
Bio-inspired surface modification of iron oxide nanoparticles for active stabilization in hydrogels.
M. Ahmadi (2020)
10.1002/ANGE.201801063
Die chemischen Grundlagen der Adhäsion von Catechol
J. Saiz-Poseu (2019)
10.1038/s41467-019-13115-3
Extravascular gelation shrinkage-derived internal stress enables tumor starvation therapy with suppressed metastasis and recurrence
K. Zhang (2019)
10.1002/adhm.201700845
Advances in Magnetic Nanoparticles for Biomedical Applications.
V. Cardoso (2018)
10.1021/acsami.7b09237
Multiligand Metal-Phenolic Assembly from Green Tea Infusions.
Md Arifur Rahim (2018)
10.1021/acsami.7b04428
A Bioinspired Alginate-Gum Arabic Hydrogel with Micro-/Nanoscale Structures for Controlled Drug Release in Chronic Wound Healing.
Mi Li (2017)
Design, synthesis, and characterization of photoresponsive materials usingcoordination bonds and other supramolecular interactions
A. Razgoniaev (2017)
Mechanics at Soft Interfaces
A. Pandey (2018)
10.1109/TNANO.2019.2904583
Nanoscale Multiparametric Imaging of Peptide-Assembled Nanofibrillar Hydrogels by Atomic Force Microscopy
M. Li (2019)
10.1016/J.APSUSC.2018.08.039
TiO2 nanoscale ionic materials using mussel adhesive proteins inspired ligand
Wu Jun-jie (2018)
10.1002/MACP.201600584
Cross‐Linking Dynamics of Cellulose Nanofibrils‐Based Transient Network Hydrogels: A Study of pH Dependence
Aishu Yin (2017)
10.1021/ACS.CHEMMATER.6B03676
Switch of Surface Adhesion to Cohesion by Dopa-Fe3+ Complexation, in Response to Microenvironment at the Mussel Plaque/Substrate Interface
Byeongseon Yang (2016)
10.1002/APP.44963
Strengthening mechanism of poly(acrylamide)/graphene oxide/laponite dual nanocomposite hydrogels
Jing Ling (2017)
10.1021/ACSMACROLETT.8B00370
Brønsted-Acid-Catalyzed Exchange in Polyester Dynamic Covalent Networks
J. L. Self (2018)
10.1016/J.EURPOLYMJ.2019.05.033
Hydrogels with self-healing ability, excellent mechanical properties and biocompatibility prepared from oxidized gum arabic
Yunyun Wang (2019)
10.1016/j.memsci.2020.117857
Polyphenol-metal manipulated nanohybridization of CNT membranes with FeOOH nanorods for high-flux, antifouling and self-cleaning oil/water separation
X. Zhao (2020)
10.1021/ACS.MACROMOL.7B00304
High-Toughness Polycation Cross-Linked Triblock Copolymer Hydrogels
Yaoyao Chen (2017)
10.1002/macp.201900329
Activation Energy for Dissociation of Hydrogen‐Bonding Crosslinkers in Phase‐Change Salogels: Dynamic Light Scattering versus Rheological Studies
Parvin Karimineghlani (2019)
10.1088/1361-648X/ab6d12
First-order "hyper-selective" binding transition of multivalent particles under force.
Tine Curk (2020)
10.1016/j.jmbbm.2017.07.029
Strain rate dependent hyperelastic stress-stretch behavior of a silica nanoparticle reinforced poly (ethylene glycol) diacrylate nanocomposite hydrogel.
Yuexing Zhan (2017)
10.1016/J.POLYMER.2017.07.044
Doubly-crosslinked, emulsion-templated hydrogels through reversible metal coordination
Tao Zhang (2017)
10.1021/ACS.CHEMMATER.7B05246
Enhanced Water Retention Maintains Energy Dissipation in Dehydrated Metal-Coordinate Polymer Networks: Another Role for Fe-Catechol Cross-Links?
S. Kim (2018)
10.1002/cplu.202000468
A Reductive Supramolecular Hydrogel: A Platform for Facile Fabrication of Diverse Metal-Nanoparticle-Decorated Conductive Networks with Spatiotemporal Control.
P. Wang (2020)
10.1016/j.cclet.2020.02.032
Anti-inflammatory catecholic chitosan hydrogel for rapid surgical trauma healing and subsequent prevention of tumor recurrence
G. He (2020)
10.1002/adhm.201700973
Moldable Hyaluronan Hydrogel Enabled by Dynamic Metal-Bisphosphonate Coordination Chemistry for Wound Healing.
L. Shi (2018)
10.1002/anie.201608413
Metal-Phenolic Supramolecular Gelation.
Md Arifur Rahim (2016)
10.1021/ACS.MACROMOL.6B01607
Polymer Structure Dependent Hierarchy in PolyMOC Gels
A. Zhukhovitskiy (2016)
10.1002/ADFM.201703826
Supertough Hybrid Hydrogels Consisting of a Polymer Double-Network and Mesoporous Silica Microrods for Mechanically Stimulated On-Demand Drug Delivery
Suji Choi (2017)
10.1002/ANIE.201902900
Polymer Networks: From Plastics and Gels to Porous Frameworks.
Y. Gu (2020)
10.1016/j.biomaterials.2019.05.001
An injectable collagen-genipin-carbon dot hydrogel combined with photodynamic therapy to enhance chondrogenesis.
Zhenhui Lu (2019)
10.1007/s10570-018-1889-x
A facile preparation strategy for conductive and magnetic agarose hydrogels with reversible restorability composed of nanofibrillated cellulose, polypyrrole, and Fe3O4
K. Liu (2018)
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