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Lewis-Acid-Mediated Benzotriazole Ring Cleavage (BtRC) Strategy For The Synthesis Of 2-Aryl Benzoxazoles From N-Acylbenzotriazoles†

Anoop S. Singh, N. Mishra, D. Kumar, V. K. Tiwari
Published 2017 · Chemistry, Medicine

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A Lewis-acid-mediated ring cleavage of acylbenzotriazoles (RCOBt) followed by cyclization to corresponding benzoxazoles was achieved in good to excellent yields. The reaction was found consistent with the milligram to gram scale.
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