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Blue Light-mediated Manipulation Of Transcription Factor Activity In Vivo.

S. Masuda, Y. Nakatani, Shukun Ren, Mikiko Tanaka
Published 2013 · Biology, Medicine

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We developed a novel technique for manipulating the activity of transcription factors with blue light (termed "PICCORO") using the bacterial BLUF-type photoreceptor protein PixD. The chimeric dominant-negative T-box transcription factor No Tail formed heterologous complexes with a PixD decamer in a light-dependent manner, and these complexes affected transcription repressor activity. When applied to zebrafish embryos, PICCORO permitted regulation of the activity of the mutant No Tail in response to 472-nm light provided by a light-emitting diode.
This paper references
Active repression of transcription by the engrailed homeodomain protein.
J. Jaynes (1991)
Active repression
J. B. Jaynes (1991)
Functional domains of the Drosophila Engrailed protein.
K. Han (1993)
The zebrafish book : a guide for the laboratory use of zebrafish (Danio rerio)
M. Westerfield (1995)
Stages of embryonic development of the zebrafish
C. Kimmel (1995)
Crystallographic structure of the T domain–DNA complex of the Brachyury transcription factor
C. Müller (1997)
Molecular identification of spadetail: regulation of zebrafish trunk and tail mesoderm formation by T-box genes.
Kevin J P Griffin (1998)
Photo-mediated gene activation using caged RNA/DNA in zebrafish embryos
H. Ando (2001)
A light-switchable gene promoter system
S. Shimizu-Sato (2002)
The use of inducible engrailed fusion proteins to study the cellular functions of eukaryotic transcription factors.
E. Vickers (2002)
The use of inducible
E. R. Vickers (2002)
An interacting network of T-box genes directs gene expression and fate in the zebrafish mesoderm
L. Goering (2003)
Biochemical characterization of the major adenylyl cyclase, Cya1, in the cyanobacterium Synechocystis sp. PCC 6803
S. Masuda (2004)
Light-induced structural changes in a putative blue-light receptor with a novel FAD binding fold sensor of blue-light using FAD (BLUF); Slr1694 of synechocystis sp. PCC6803.
S. Masuda (2004)
A transposon-mediated gene trap approach identifies developmentally regulated genes in zebrafish.
K. Kawakami (2004)
A transposon-mediated gene
N. Matsuda (2004)
Biochemical and functional characterization of BLUF-type flavin-binding proteins of two species of cyanobacteria.
K. Okajima (2005)
Functional Dissection of the Tol2 Transposable Element Identified the Minimal cis-Sequence and a Highly Repetitive Sequence in the Subterminal Region Essential for Transposition
Akihiro Urasaki (2006)
Light-controlled gene silencing in zebrafish embryos.
Ilya A. Shestopalov (2007)
PixE promotes dark oligomerization of the BLUF photoreceptor PixD
H. Yuan (2008)
Crucial role in light signal transduction for the conserved Met93 of the BLUF protein PixD/Slr1694.
S. Masuda (2008)
PixE promotes dark
H. Yuan (2008)
A gene regulatory network directed by zebrafish No tail accounts for its roles in mesoderm formation
R. H. Morley (2009)
Induction of protein-protein interactions in live cells using light
M. Yazawa (2009)
Rapid blue light induction of protein interactions in living cells
M. J. Kennedy (2010)
A Synthetic Optogenetic Transcription Device Enhances Blood-Glucose Homeostasis in Mice
Haifeng Ye (2011)
Manipulation of gene expression in zebrafish using caged circular morpholino oligomers
Y. Wang (2012)
Spatiotemporal control of gene expression by a light-switchable transgene system
X. Wang (2012)
Light-Inducible Spatiotemporal Control of Gene Activation by Customizable Zinc Finger Transcription Factors
Lauren R. Polstein (2012)
A gene regulatory network model for control
J. Krohn (2013)
A predicted structure for the PixD-PixE complex determined by homology modeling, docking simulations, and a mutagenesis study.
Shukun Ren (2013)
Light Detection and Signal Transduction in the BLUF Photoreceptors.
S. Masuda (2014)

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