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Bioactive Glass Granules S53P4 In Osteotomy Le Fort I

E. L. de Souza Cruz, Fernando Jordão de Souza, Lucas Machado de Menezes, F. Tuji, J. T. Carneiro
Published 2020 · Medicine

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We evaluated bioactive glass graft (S53P4) in patients undergoing Le Fort I osteotomy, with non-grafted patients as controls. Computed tomography facial scans of the 25 patients submitted for Le Fort I were divided into two groups: Group 1—S53P4 group and Group 2—without grafting. CT scans were analyzed in the immediate postoperative period (T1) and 6 months later (T2), for linear bone gap measurements, tomographic radiodensity and behavior of the maxillary sinus. A Kruskal–Wallis test on bone gap data adopted α significance levels ( p  ≤ 0.05). The Friedman test ( p  ≤ 0.05) was used to evaluate sinus reaction cores. For gap measurements, we observed a decrease in median data between T1 and T2 in both groups, with statistical significances observed between groups in T0; G1 presented statistical difference in its two studied times ( p  ≤ 0.0001). For bone density, the studied data behaved inversely. G1′s bone density decreased from T1 to T2, whereas in G2 there was an increase from T1 to T2. S53P4 did not elicit increased reactions and/or sinus infections in the G1 group ( p  ≥ 1.00). S53P4 did not impact on Le Fort I osteotomies as a coadjuvant and a favorable factor in bone formation, and appeared innocuous in the maxillary sinus.
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