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Structure–activity Relationship Study Of Dendritic Polyglycerolamines For Efficient SiRNA Transfection

Fatemeh Sheikhi Mehrabadi, Ole Hirsch, Reiner Zeisig, Paola Posocco, Erik Laurini, Sabrina Pricl, Rainer Haag, Wolfgang Kemmner, Marcelo Calderón

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Structure–activity relationship studies were performed through in vitro, in silico, and in vivo analysis in order to evaluate the gene transfection potential of dendritic polyglycerolamines with different amine loadings.