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An Injectable PEG-based Hydrogel Synthesized By Strain-promoted Alkyne–azide Cycloaddition For Use As An Embolic Agent

Xin Su, Linlin Bu, Hui Dong, Shuangli Fu, Renxi Zhuo, Zhenlin Zhong

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Cyclooctyne and azide functionalized PEGs are prepared by ring-opening polymerization. They form a biodegradable hydrogel in situ to temporarily block rabbit ear vessels.