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Killing Cancer Cells Using Nanotechnology: Novel Poly(I:C) Loaded Liposome–silica Hybrid Nanoparticles

Valentina Colapicchioni, Sara Palchetti, Daniela Pozzi, Elettra Sara Marini, Anna Riccioli, Elio Ziparo, Massimiliano Papi, Heinz Amenitsch, Giulio Caracciolo

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Synthesized core–shell liposome–silica hybrid nanoparticles (LSH NPs), when loaded with the anti-cancer polyinosinic–polycytidylic acid (poly(I:C)), exhibit high anti-tumoral activity in prostate and breast cancer cells.