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1,3-Dipolar Cycloadditions: Applications To The Synthesis Of Antiviral Agents.

C. Nájera, J. Sansano
Published 2009 · Chemistry, Medicine

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In the present perspective the advances and real possibilities of 1,3-dipolar cycloadditions as key steps in the total synthesis of virus inhibitors are described. Azides, nitrones, and azomethine ylides are the most appropriate 1,3-dipoles for the synthesis of privileged structures with the highest biological responses against viruses.
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