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HSA Coated MnO Nanoparticles With Prominent MRI Contrast For Tumor Imaging.
J. Huang, J. Xie, K. Chen, Lihong Bu, S. Lee, Z. Cheng, X. Li, X. Chen
Published 2010 · Chemistry, Medicine
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We report in this Communication a facile, two-step surface modification strategy to achieve manganese oxide nanoparticles with prominent MRI T1 contrast. In a U87MG glioblastoma xenograft model, we confirmed that the particles can accumulate efficiently in tumor area to induce effective T1 signal alteration.
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