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Inhibitor Structure-guided Design And Synthesis Of Near-infrared Fluorescent Probes For Monoamine Oxidase A (MAO-A) And Its Application In Living Cells And In Vivo

Zhengmin Yang, Wenxiu Li, Hua Chen, Qingyuan Mo, Jun Li, Shulin Zhao, Cheng Hou, Jiangke Qin, Guifa Su

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A series of near-infrared fluorescent probes based on inhibitor (clorgyline) structure-guided design were synthesized for the specific detection of MAO-A in cells and in vivo.