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Amine-catalyzed And Functional Group-controlled Chemo- And Regioselective Synthesis Of Multi-functionalized CF3-benzene Via A Metal-free Process

Fu Peng, Qian Zhao, Wei Huang, Shuai-Jiang Liu, Ya-Jun Zhong, Qing Mao, Nan Zhang, Gu He, Bo Han

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A novel strategy for the synthesis of CF3-containing multi-substituted benzenes with high chemo- and regioselectivities under metal-free and air-tolerant conditions was established.