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Development Of Potent Inhibitors For Strigolactone Receptor DWARF 14

Masahiko Yoshimura, Sojung F. Kim, Ryosuke Takise, Shuhei Kusano, Sakuya Nakamura, Masanori Izumi, Akiko Yagi, Kenichiro Itami, Shinya Hagihara

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Strigolactones (SLs) are plant hormones that suppress shoot branching through perception by their receptor protein DWARF 14 (D14). Based on the binding model of DL1, a small-molecule D14 inhibitor, more potent compounds were developed.