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Three-component Heteroannulation For Tetrasubstituted Furan Construction Enabled By Successive Defluorination And Dual Sulfonylation Relay

Song-Zhou Cai, Danhua Ge, Li-Wen Sun, Weidong Rao, Xin Wang, Zhi-Liang Shen, Xue-Qiang Chu

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An efficient method for the facile assembly of fluoroalkylated tetrasubstituted furan derivatives via a three-component cascade reaction of polyfluoroalkyl peroxide with sulfinates was developed.