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A Dose Of 75 μg/kg/d Of I.v. Anti‐D Increases The Platelet Count More Rapidly And For A Longer Period Of Time Than 50 μg/kg/d In Adults With Immune Thrombocytopenic Purpura

G. Newman, M. Novoa, E. M. Fodero, M. Lesser, B. Woloski, J. Bussel
Published 2001 · Medicine

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Treatment with 75 μg/kg/d intravenous (i.v.) anti‐D was compared with 50 μg/kg/d in a prospective randomized study of 27 RhD‐positive, human immunodeficiency virus‐negative, adult, acute, non‐splenectomized patients with immune thrombocytopenic purpura (ITP) and platelet counts ≤ 30 × 109/l. The higher dose resulted in greater median d 1 (43 × 109/l vs. 7·5 × 109/l; P = 0·012) and d 7 (153 × 109/l vs. 64·5 × 109/l; P = 0·001) platelet increases despite no greater haemoglobin decrease. Children with acute ITP receiving 75 μg/kg/d had overnight platelet increases in seven out of nine cases. The duration of effect at the 75 μg/kg/d dose was 46 d vs. 21 d (P = 0·03). Adverse events were mild to moderate and ameliorated with prednisone and acetaminophen premedication.
This paper references
STERILISATION BY STEAM UNDER INCREASED PRESSURE; A THIRD COMMUNICATION TO THE MEDICAL RESEARCH COUNCIL BY THE WORKING PARTY ON PRESSURE-STEAM STERILISERS.
M. Marshall (1964)
10.1016/S0140-6736(83)90175-7
EFFECT OF INTRAVENOUS IMMUNOGLOBULIN IN IMMUNE THROMBOCYTOPENIA Competitive Inhibition of Reticuloendothelial System Function by Sequestration of Autologous Red Blood Cells?
A. Salama (1983)
10.1016/S0022-3476(85)80231-6
Treatment of acute idiopathic thrombocytopenia of childhood with intravenous infusions of gammaglobulin.
J. Bussel (1985)
10.1182/blood.v71.5.1499.1499
Anti-RH immunoglobulin therapy for human immunodeficiency virus-related immune thrombocytopenic purpura.
E. Oksenhendler (1988)
10.1182/blood.v77.9.1884.bloodjournal7791884
Intravenous anti-D treatment of immune thrombocytopenic purpura: analysis of efficacy, toxicity, and mechanism of effect.
J. Bussel (1991)
10.1016/S0140-6736(94)92205-5
Randomised trial of intravenous immunoglobulin G, intravenous anti-D, and oral prednisone in childhood acute immune thrombocytopenic purpura
V. Blanchette (1994)
Randomized trial of intravenous immunoglobulin G , Intravenous anti - D , and oral prednisone in childhood acute immune thrombocytopenic purpura
V. Blanchette (1994)
Randomized trial of intravenous immunoglobulin G, Intravenous anti-D, and oral prednisone in childhood acute
V. Blanchette (1994)
10.1182/BLOOD.V88.1.3.BLOODJOURNAL8813
Idiopathic thrombocytopenic purpura: a practice guideline developed by explicit methods for the American Society of Hematology.
J. George (1996)
Idiopathic thrombocytopenic purpura: a practice guideline developed by explicit methods for
J. N. George (1996)
Idiopathic thrombocytopenic purpura: a practice guideline developed by explicit methods for the
J N George (1996)
10.1016/s0887-7963(97)80114-9
Intravenous anti-D treatment of immune thrombocytopenic purpura: experience in 272 patients.
A. Scaradavou (1997)
10.1182/BLOOD.V89.8.2689
Intravenous Anti-D Treatment of Immune Thrombocytopenic Purpura: Experience in 272 Patients
A. Scaradavou (1997)
10.1016/S0022-3476(99)70367-7
Treatment of childhood acute immune thrombocytopenic purpura with anti-D immune globulin or pooled immune globulin.
M. Tarantino (1999)
10.1097/00043426-200001000-00011
Self-reported diagnostic and management strategies in childhood idiopathic thrombocytopenic purpura: results of a survey of practicing pediatric hematology/oncology specialists.
S. Vesely (2000)
10.1182/BLOOD.V95.8.2523
Acute onset hemoglobinemia and/or hemoglobinuria and sequelae following Rho(D) immune globulin intravenous administration in immune thrombocytopenic purpura patients
A. Gaines (2000)



This paper is referenced by
10.32553/IJMBS.V3I12.841
DENGUE FEVER: A TRIGGERING FACTOR FOR IMMUNE THROMBOCYTOPENIC PURPURA IN ADULT FEMALE- A RARE CASE REPORT
Arth H Shah (2019)
10.1055/s-0039-1684031
First-Line Therapy for Immune Thrombocytopenia.
Siraj Mithoowani (2019)
Can Some First-Line Therapies Induce Long-Term Remission ?
Siraj Mithoowani (2019)
10.1055/s-0039-1700512
Immune Thrombocytopenia in Adults: Modern Approaches to Diagnosis and Treatment.
H. Al-Samkari (2019)
10.1177/1753495X17709188
Refractory severe immune thrombocytopenia in a twin pregnancy
P. Harrington (2018)
Clinical Practice Updates in the Management Of Immune Thrombocytopenia.
Ayesha M. Khan (2017)
10.1080/14728214.2017.1294158
Emerging drugs for immune thrombocytopenia (ITP)
A. Salama (2017)
10.3324/haematol.2017.174615
Comparison of up-front treatments for newly diagnosed immune thrombocytopenia -a systematic review and network meta-analysis
Y. Arai (2017)
10.5812/COMPREPED.12334
Comparison of the Therapeutic Effect of Anti-D IG and IVIG in Children with Acute Immune Thrombocytopenic Purpura Attending a Children’s Medical Center: A Randomized, Double-Blind, Controlled Clinical Trial
L. Koochakzadeh (2017)
10.1080/21678707.2016.1247691
Immune thrombocytopenia: a comprehensive review from pathophysiology to promising treatment modalities
Hassan M. Moukhadder (2016)
10.1053/j.seminhematol.2016.04.019
Anti-D treatment for pediatric immune thrombocytopenia: Is the bad reputation justified?
J. Yacobovich (2016)
10.1111/trf.13185
How we use WinRho in patients with idiopathic thrombocytopenic purpura
B. Stotler (2015)
10.1055/s-0034-1544001
Can immune thrombocytopenia be cured with medical therapy?
A. Cuker (2015)
10.3109/08880018.2015.1040931
Initial Management of Childhood Acute Immune Thrombocytopenia: Single-Center Experience of 32 Years
I. Yıldız (2015)
10.17463/RCM.2014.02.005
Comparison of dexamethasone and anti-D immune globulin for immune thrombocytopenia purpura in children
Abdollah Banihashem (2014)
10.1016/j.autrev.2014.01.026
Diagnosis and classification of immune-mediated thrombocytopenia.
Ernest N. Lo (2014)
10.1007/978-3-0348-0706-7_11
B-Cell Targeted Therapies in Autoimmune Cytopenias and Thrombosis
B. Matta (2013)
10.1016/B978-0-12-387837-3.00040-7
Immune Thrombocytopenia (ITP)
B. Psaila (2013)
10.1182/asheducation-2013.1.283
Is anti-D immunoglobulin still a frontline treatment option for immune thrombocytopenia?
J. Despotovic (2013)
10.1002/pbc.24574
RHD zygosity predicts degree of platelet response to anti‐D immune globulin treatment in children with immune thrombocytopenia
J. Despotovic (2013)
DIJAGNOSTIČKI PRISTUP I LIJEČENJE IMUNE TROMBOCITOPENIJE U ODRASLOJ DOBI
S. O. Kolonić (2013)
10.1586/17474086.2013.841076
Contemporary treatment of immune thrombocytopenia
M. Izak (2013)
La place des nouvelles molécules dans la prise en charge thérapeutique du purpura thrombopénique idiopathique
Angélique Carniel (2013)
10.1097/MBC.0b013e32835e5337
A comparison of intravenous immunoglobulin (2 g/kg totally) and single doses of anti-D immunoglobulin at 50 &mgr;g/kg, 75 &mgr;g/kg in newly diagnosed children with idiopathic thrombocytopenic purpura: Ankara hospital experience
Bulent Alioglu (2013)
10.1186/1752-1947-7-91
Refractory immune thrombocytopenia successfully treated with high-dose vitamin D supplementation and hydroxychloroquine: two case reports
B. Bockow (2013)
10.1182/blood-2012-06-438804
Rozrolimupab, a mixture of 25 recombinant human monoclonal RhD antibodies, in the treatment of primary immune thrombocytopenia.
T. Robak (2012)
antibodies, in the treatment of primary immune thrombocytopenia Rozrolimupab, a mixture of 25 recombinant human monoclonal RhD
Torben Peter Frandsen (2012)
10.1007/s11239-012-0801-z
Comparison of anti-D immunoglobulin, methylprednisolone, or intravenous immunoglobulin therapy in newly diagnosed pediatric immune thrombocytopenic purpura
Muhittin Çelik (2012)
Canadian cost- utility analysis of intravenous immunoglobulin for acute childhood idiopathic thrombocytopenic purpura.
G. Blackhouse (2012)
10.1002/9781118356807.CH15
Rh (D) Immunoglobulin
M. Genereux (2012)
10.4274/TPA.1659
2011 yılında çocukluk çağı immün trombositopenik purpura hastalığı izlem ve tedavisinde değişiklikler
T. Celkan (2012)
El número necesario a tratar como medida de efecto en el tratamiento de la trombocitopenia inmune primaria
G. Vizcaíno (2012)
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