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Sarcomatoid Mesothelioma And Its Histological Mimics: A Comparative Immunohistochemical Study

D. Lucas, H. Pass, S. K. Madan, N. V. Adsay, A. Wali, P. Tabaczka, F. Lonardo
Published 2003 · Biology, Medicine

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Aims:  Differentiating sarcomatoid mesothelioma from other pleural‐based spindle cell tumours by light microscopy can be challenging, especially in a biopsy. The role of immunohistochemistry in this differential diagnosis is not as well defined as it is for distinguishing epithelioid mesothelioma from adenocarcinoma. In this study, we investigate the utility of diagnostic immunohistochemistry for distinguishing sarcomatoid mesothelioma from its histological mimics, high‐grade sarcoma and pulmonary sarcomatoid carcinoma.
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