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Predictors Of Post-ERCP Complications In Patients With Suspected Choledocholithiasis.

S. Mehta, E. Pavone, J. Barkun, S. Bouchard, A. Barkun
Published 1998 · Medicine

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BACKGROUND AND STUDY AIMS Determinants of complications after endoscopic retrograde cholangiopancreatography (ERCP) have not yet been completely characterized. PATIENTS AND METHODS Data were collected from an endoscopic database. Univariate analysis and multivariate logistic regression analysis were used to generate the best model of independent predictors of post-ERCP pancreatitis. RESULTS The database included 1239 ERCP examinations carried out to investigate suspected choledocholithiasis over a five-year period. From these, 45 patients who developed post-ERCP complications were compared to a random sample of 486 patients who had undergone an uncomplicated ERCP for suspected choledocholithiasis. Univariate analysis demonstrated significant differences between the two patient groups for the following factors: age, using a cut-off point of 59 years (27% vs. 51%, P = 0.002), pancreatic channel opacification (73% vs. 58%, P = 0.05), and absence of common bile duct stones (41% vs. 24%, P = 0.03). Using multivariate logistic regression, the best model for predicting post-ERCP pancreatitis in patients undergoing sphincterotomy included age under 59 years (P = 0.04), and absence of a common bile duct stone (P = 0.004). The model yielded probabilities of developing post-sphincterotomy pancreatitis that ranged from 2.8% if no predictor was present, to 27% when both predictors were present. Among patients in whom a sphincterotomy was not performed, the only significant independent predictor found was pancreatic channel opacification (P = 0.05). CONCLUSION Age under 59 years, pancreatic channel opacification, and an absence of common bile duct stones at ERCP are all independent predictors of post-ERCP pancreatitis.

This paper is referenced by
Endoscopic retrograde cholangiopancreatography in the elderly.
J. A. Avila-Funes (2005)
Are we meeting the standards set for endoscopy? Results of a large-scale prospective survey of endoscopic retrograde cholangio-pancreatograph practice
E. Williams (2007)
Prevention of post-endoscopic retrograde cholangiopancreatography pancreatitis by pancreatic duct stenting: should it be routine?
R. Kozarek (2011)
Adverse outcomes of ERCP.
M. Freeman (2002)
Risk factors for complications after ERCP: a multivariate analysis of 11,497 procedures over 12 years.
P. Cotton (2009)
Surgical management of ERCP-related complications
A. Fathi (2011)
Pancreatitis with an unusual fatal complication following endoscopic retrograde cholangiopancreaticography: a case report
B. Kanen (2008)
Is the double‐guidewire technique superior to the pancreatic duct guidewire technique in cases of pancreatic duct opacification?
R. Tanaka (2013)
The comparison between combination of pancreatic stent and nsaid with nsaid alone in preventing post ERCP pancreatitis
Alizadeh Arash Heidarnezhad (2018)
Post-ERCP pancreatitis: Reduction by routine antibiotics
S. Räty (2001)
Guidelines on the management of common bile duct stones (CBDS)
E. Williams (2008)
ERCP as an outpatient treatment: a review.
S. Jeurnink (2008)
Development and validation of a risk prediction model and scoring system for post-endoscopic retrograde cholangiopancreatography pancreatitis.
Ruhua Zheng (2020)
Frequency of common factors for post endoscopic retrograde cholangiopancreatography pancreatitis.
Syed Afzal-ul-Haq Haqqi (2011)
Prevention and Intervention Strategies in Acute Pancreatitis
M. Besselink (2005)
Factores de riesgo predictores para complicaciones post-colangiopancreatografía retrógrada endoscópica
Alan Mijail Langarica Zárate (2016)
T. Nishino (2008)
Risk Factors for Post-ERCP Pancreatitis: A Prospective Multicenter Study
Chi-Liang Cheng (2006)
Pancreatitis Potentially Associated Drugs as a Risk Factor for Post–Endoscopic Retrograde Cholangiopancreatography Pancreatitis: A Prospective Cohort Study
D. Sigounas (2013)
Prophylaxis of post-endoscopic retrograde cholangiopancreatography pancreatitis by an endoscopic pancreatic spontaneous dislodgement stent.
A. Sofuni (2007)
Aplicación de una escala pronóstica para complicaciones postcolangiopancreatografía retrógrada endoscópica
Alan Mijail Langarica Zárate (2016)
Feasibility of Temporary Pancreatic Stenting after Early Endoscopic Retrograde Cholangiopancreatography in Patients with Acute Biliary Pancreatitis.
J. Lee (2017)
Prophylactic pancreatic stent placement and post-ERCP pancreatitis: an updated meta-analysis
T. Mazaki (2013)
Quality indicators, including complications, of ERCP in a community setting: a prospective study.
Joshua B Colton (2009)
Acute pancreatitis – the most common complication after endoscopic retrograde cholangiopancreatography
Laura Maðalaitë (2008)
Evaluation of recombinant platelet-activating factor acetylhydrolase for reducing the incidence and severity of post-ERCP acute pancreatitis.
S. Sherman (2009)
Are drugs a risk factor of post-ERCP pancreatitis?
P. Perney (2003)
Brushing the distal biliary stricture in the surrounding of the papilla increased the risk of post-endoscopic retrograde cholangiopancreatography pancreatitis: A retrospective study using propensity score analysis
K. Kato (2017)
Intravenous Synthetic Secretin Reduces the Incidence of Pancreatitis Induced by Endoscopic Retrograde Cholangiopancreatography
P. Jowell (2011)
The role of gallbladder, cholecystokinin and microbes in gallstone and post-ERCP pancreatitis
S. Räty (2000)
Randomised clinical trial: MRCP‐first vs. ERCP‐first approach in patients with suspected biliary obstruction due to bile duct stones
M. Bhat (2013)
[Efficacy and complications of double guidewire technique in biliary tract cannulation].
E. Guzmán-Calderón (2017)
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