Online citations, reference lists, and bibliographies.

A Randomized Comparison Of Coronary-stent Placement And Balloon Angioplasty In The Treatment Of Coronary Artery Disease. Stent Restenosis Study Investigators.

David L Fischman, M. Bonilla León, Donald S. Baim, Richard A. Schatz, Michael P Savage, Israel Penn, K Detre, Luca Veltri, Deborah Ricci, Masakiyo Nobuyoshi
Published 1994 · Medicine
Cite This
Download PDF
Analyze on Scholarcy
BACKGROUND Coronary-stent placement is a new technique in which a balloon-expandable, stainless-steel, slotted tube is implanted at the site of a coronary stenosis. The purpose of this study was to compare the effects of stent placement and standard balloon angioplasty on angiographically detected restenosis and clinical outcomes. METHODS We randomly assigned 410 patients with symptomatic coronary disease to elective placement of a Palmaz-Schatz stent or to standard balloon angioplasty. Coronary angiography was performed at base line, immediately after the procedure, and six months later. RESULTS The patients who underwent stenting had a higher rate of procedural success than those who underwent standard balloon angioplasty (96.1 percent vs. 89.6 percent, P = 0.011), a larger immediate increase in the diameter of the lumen (1.72 +/- 0.46 vs. 1.23 +/- 0.48 mm, P < 0.001), and a larger luminal diameter immediately after the procedure (2.49 +/- 0.43 vs. 1.99 +/- 0.47 mm, P < 0.001). At six months, the patients with stented lesions continued to have a larger luminal diameter (1.74 +/- 0.60 vs. 1.56 +/- 0.65 mm, P = 0.007) and a lower rate of restenosis (31.6 percent vs. 42.1 percent, P = 0.046) than those treated with balloon angioplasty. There were no coronary events (death; myocardial infarction; coronary-artery bypass surgery; vessel closure, including stent thrombosis; or repeated angioplasty) in 80.5 percent of the patients in the stent group and 76.2 percent of those in the angioplasty group (P = 0.16). Revascularization of the original target lesion because of recurrent myocardial ischemia was performed less frequently in the stent group than in the angioplasty group (10.2 percent vs. 15.4 percent, P = 0.06). CONCLUSIONS In selected patients, placement of an intracoronary stent, as compared with balloon angioplasty, results in an improved rate of procedural success, a lower rate of angiographically detected restenosis, a similar rate of clinical events after six months, and a less frequent need for revascularization of the original coronary lesion.

This paper is referenced by
Three-Dimensional Computational Fluid Dynamics Modeling of Alterations in Coronary Wall Shear Stress Produced by Stent Implantation
John F. LaDisa (2004)
Coronary artery stents: identification and evaluation
Jagdish W Butany (2005)
Elevated preprocedural high-sensitivity C-reactive protein levels are associated with neointimal hyperplasia and restenosis development after successful coronary artery stenting.
Young Joon Hong (2005)
Clinical outcomes of stents versus balloon angioplasty in non-acute coronary artery disease. A meta-analysis of randomized controlled trials.
Alain J. Nordmann (2004)
Role of IN-1233 in the prevention of neointimal hyperplasia after stent placement in a rat artery model.
Hyun-Jung Yoon (2011)
Multi-Link Vision stent vs. first-generation drug-eluting stents: systematic review and meta-analysis.
Luca Testa (2011)
Impact of intravascular ultrasound guidance in stent deployment on 6-month restenosis rate: a multicenter, randomized study comparing two strategies--with and without intravascular ultrasound guidance. RESIST Study Group. REStenosis after Ivus guided STenting.
François Schiele (1998)
Recent developments in drug-eluting stents
Yue Li (2011)
Optimizing stent expansion with new stent delivery systems.
Yuzuru Takano (2001)
Znaczenie optymalizacji wyników przeznaczyniowej rewaskularyzacji serca pod kontrolą ultrasonografii wewnątrznaczyniowej w zapobieganiu restenozie
Adam Sukiennik (2000)
Anti-thrombogenic Study of Ultrathin Monoethylene Glycol Adlayer on 316L Stainless Steel against Whole Human Blood
Tairan Yang (2015)
Chest pain after coronary interventional procedures
Allen Jeremias (1999)
Stent directo sin predilatación. Experiencia en 300 lesiones
Jose M. de la Torre Hernandez (1999)
Initial Results after Implantation of Coronary Artery Stents with Antiplatelet Agents
Ji won Son (1998)
Percutaneous Coronary Intervention in Diabetics
Juhana Karha (2004)
Nart F. Abida (2007)
Coronary Irradiation for the Prevention of Restenosis after Percutaneous Transluminal Coronary Angioplasty
Ki Bae Seung (1998)
Statin therapy is associated with reduced restenosis rates after coronary stent implantation in carriers of the Pl(A2)allele of the platelet glycoprotein IIIa gene.
Dirk Walter (2001)
Quality of life and ethics-patients with ischemic heart disease
Lars Westin (2005)
Genetic risk factors and restenosis after percutaneous coronary interventions
Adnan Kastrati (2000)
Microsystems for drug and gene delivery
Michael L. Reed (2004)
RIBONUCLEOTIDE REDUCTASE INHIBITORS FOR RESTENOSIS MASTER ’ S THESIS Presented in Partial Fulfillment of the Requirements for the Degree Master in Science in The Graduate School of The Ohio State University By
Megan Marie Mutchler (2008)
Stent placement compared with balloon angioplasty for obstructed coronary bypass grafts . Saphenous Vein De Novo Trial Investigators
ohn (2017)
Design optimisation for stent manufacture
Muhammad Farhan Khan (2018)
Intraarterial beta irradiation to reduce restenosis after PTCA
Vitali Dr Verin (2009)
Novel devices Bioresorbable scaffolds : rationale , current status , challenges , and future
Javaid Iqbal (2014)
A focused review on materials and generations of coronary stents
Hamidreza Shirzadfar (2018)
Cutting Balloon: Review on Principles and Background of Use in Peripheral Arteries
Manfred Cejna (2004)
Percutaneous stent implantation for treating multivessel coronary disease in patients with and without involvement of the proximal segment of the anterior descending coronary artery.
Sandro Salgueiro (2002)
Coated stents for the prevention of restenosis: Part I.
Mohan N Babapulle (2002)
Clopidogrel with Aspirin Is the Optimal Antiplatelet Regimen for Intracoronary Stenting
Steven R. Steinhubl (1999)
Application of 64-slice spiral computed tomography angiography in a follow-up evaluation after coronary stent implantation: A Chinese clinical study
F. Huang (2019)
See more
Semantic Scholar Logo Some data provided by SemanticScholar