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Chemistry Of The Synthetic Strigolactone Mimic GR24

Liam J. Bromhead, Jason Smith, Christopher S. P. McErlean

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This research paper describes a second-generation, enantioselective synthesis of (+)-GR24. This new strategy circumvents the need for ozonolysis, which may not be suitable for reactions performed on scale. This flexible new approach is then used to synthesise a novel bromo-GR24 analogue. Finally, the optimal solvent for making GR24 stock solutions is identified.