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The Synthesis Of 2-heteroarylimidazo[1,2-a]pyridin-3-ols And Related Compounds

LW Deady, MS Stanborough

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A reaction between pyridin-2-amine 1-oxides and phenacyl bromides has been extended to some bromoacetyl heteroaromatic compounds to form the title compounds. The reaction of some 2-amino-diazine 1-oxides with phenacyl bromides has also been studied. The imidazo[1,2-a]pyrimidine and imidazo[2,1-a]phthalazine systems have been prepared but reaction of pyrazin-2-amine 1-oxide did not give the desired cyclization.