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A Novel Closed-circular Mitochondrial DNA With Properties Of A Replicating Intermediate.

H. Kasamatsu, D. Robberson, J. Vinograd
Published 1971 · Biology, Medicine

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A fraction of the covalently closed mitochondrial DNA in mouse L cells contains a replicated heavy-strand segment that is hydrogen bonded to the circular light strand. The inserted single strand is dissociable from the circular duplex at an elevated temperature.



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