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A New Route To (±) Metoprolol

M. Gurjar, S. V. Joshi, B. S. Sastry, A. V. R. Rao
Published 1990 · Chemistry

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Abstract Synthesis of 4-(2-methoxyethyl)phenol (5) from phenol is described. The derived aryloxyallyl ether (6) is converted into (±)-metoprolol (10) by involving dihydroxylation reaction with OsO4 and NMO.
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