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A Patient-specific CT-based Finite Element Methodology To Calculate The 6D Stiffness Matrix Of Vertebral Bodies
Published 2009 · Engineering
Finite element analysis, which can predict the strength of human vertebral bodies better than DEXA, has recently been used in follow-up studies of antiresorptive or anabolic treatments (Keaveny et al. 2007). In most FE studies of vertebrae, axial compression is the loading mode of choice to investigate structural properties. However, this might not adequately reflect the various loads to which the spine is subjected during daily activities, or the increased fracture risk associated with shearing or bending loads (Whealan et al. 2000). The goal of this work is to propose a patient-specific CT-based methodology, using the currently most advanced, clinically applicable finite element approach to perform a structural investigation of the vertebral body by calculation of its full 6D stiffness matrix.