Online citations, reference lists, and bibliographies.
Referencing for people who value simplicity, privacy, and speed.
Get Citationsy
← Back to Search

On The Functional Anatomy Of The Urge-for-action

S. Jackson, Amy Parkinson, So Young Kim, Martin Schüermann, S. Eickhoff
Published 2011 · Psychology, Medicine

Save to my Library
Download PDF
Analyze on Scholarcy Visualize in Litmaps
Share
Reduce the time it takes to create your bibliography by a factor of 10 by using the world’s favourite reference manager
Time to take this seriously.
Get Citationsy
Several common neuropsychiatric disorders (e.g., obsessive-compulsive disorder, Tourette syndrome (TS), autistic spectrum disorder) are associated with unpleasant bodily sensations that are perceived as an urge for action. Similarly, many of our everyday behaviors are also characterized by bodily sensations that we experience as urges for action. Where do these urges originate? In this paper, we consider the nature and the functional anatomy of “urges-for-action,” both in the context of everyday behaviors such as yawning, swallowing, and micturition, and in relation to clinical disorders in which the urge-for-action is considered pathological and substantially interferes with activities of daily living (e.g., TS). We review previous frameworks for thinking about behavioral urges and demonstrate that there is considerable overlap between the functional anatomy of urges associated with everyday behaviors such as swallowing, yawning, and micturition, and those urges associated with the generation of tics in TS. Specifically, we show that the limbic sensory and motor regions––insula and mid-cingulate cortex––are common to all of these behaviors, and we argue that this “motivation-for-action” network should be considered distinct from an “intentional action” network, associated with regions of premotor and parietal cortex, which may be responsible for the perception of “willed intention” during the execution of goal-directed actions.
This paper references
10.1001/ARCHPSYC.1980.01780250029002
Sensory experiences of Gilles de la Tourette syndrome.
J. Bliss (1980)
Bereitschaftspotential in tic disorders: a preliminary observation.
H. Duggal (2002)
10.1007/s00429-010-0256-y
Clinical effects of insular damage in humans
Agustín Ibáñez (2010)
10.1007/978-3-540-88955-7_17
Tourette's syndrome.
K. Müller-Vahl (2009)
10.1016/j.neuroimage.2008.04.234
Sensory stimulation activates both motor and sensory components of the swallowing system
Soren Y. Lowell (2008)
10.1068/P2911RVW
Review: The Feeling of What Happens: Body, Emotion and the Making of Consciousness
Robert W. Kentridge (2000)
10.1093/brain/awp299
Altered modulation of intracortical excitability during movement preparation in Gilles de la Tourette syndrome.
K-F Heise (2010)
10.1126/SCIENCE.275.5306.1593
A Neural Substrate of Prediction and Reward
W. Schultz (1997)
10.1038/89551
Cerebral mechanisms of word masking and unconscious repetition priming
S. Dehaene (2001)
10.1007/s00408-007-9045-7
Urge-to-Cough: What Can It Teach Us About Cough?
P. Davenport (2007)
10.1212/WNL.41.2_Part_1.223
Patient perception of tics and other movement disorders
A. Lang (1991)
10.1016/j.neuropsychologia.2010.06.039
Parietal cortex coding of limb posture: In search of the body-schema
Amy Parkinson (2010)
10.1161/STROKEAHA.107.495606
Tight Link Between Our Sense of Limb Ownership and Self-Awareness of Actions
B. Baier (2008)
10.1080/17588928.2010.525627
Modulation of somatosensory perception by motor intention
A. Parkinson (2011)
10.1016/j.tics.2009.08.001
A parietal-premotor network for movement intention and motor awareness
M. Desmurget (2009)
10.3758/s13415-011-0035-0
Hearing others’ pain: neural activity related to empathy
S. Lang (2011)
10.1002/hbm.21240
Altered motor network recruitment during finger tapping in boys with tourette syndrome
V. Roessner (2012)
10.1016/j.neuropsychologia.2009.09.034
My body in the brain: A neurocognitive model of body-ownership
M. Tsakiris (2010)
10.1016/j.tins.2008.09.009
The hidden island of addiction: the insula
N. Naqvi (2009)
10.1016/j.tics.2004.07.009
Action sets and decisions in the medial frontal cortex
M. Rushworth (2004)
10.1146/annurev.neuro.29.051605.112851
Habits, rituals, and the evaluative brain.
A. Graybiel (2008)
10.1038/nn896
Unmyelinated tactile afferents signal touch and project to insular cortex
H. Olausson (2002)
10.1016/S1364-6613(02)01907-1
Abnormalities in the awareness of action
Sarah-Jayne Blakemore (2002)
10.1093/BRAIN/78.4.445
The insula; further observations on its function.
W. Penfield (1955)
10.1093/CERCOR/12.4.376
Representation of pain and somatic sensation in the human insula: a study of responses to direct electrical cortical stimulation.
K. Ostrowsky (2002)
10.1098/rstb.2005.1763
Glucose-sensing neurons of the hypothalamus
D. Burdakov (2005)
10.1016/j.brat.2008.07.005
Examining the impact of distraction on tic suppression in children and adolescents with Tourette syndrome.
Christine A. Conelea (2008)
10.1038/81497
Computational principles of movement neuroscience
D. Wolpert (2000)
10.1016/j.neuroimage.2004.10.022
Yearning to yawn: the neural basis of contagious yawning
M. Schürmann (2005)
10.1016/S0959-4388(01)00266-5
Imaging the premotor areas
N. Picard (2001)
10.1016/j.neuropsychologia.2006.01.009
Parietal updating of limb posture: An event-related fMRI study
Asa Pellijeff (2006)
10.1038/nn1160
Altered awareness of voluntary action after damage to the parietal cortex
A. Sirigu (2004)
10.1176/AJP.150.1.98
Premonitory urges in Tourette's syndrome.
J. Leckman (1993)
10.1016/S0165-0173(96)00011-2
Circuitry and functional aspects of the insular lobe in primates including humans
J. R. Augustine (1996)
10.1177/1073858407299288
The Neural Basis of Inhibition in Cognitive Control
A. Aron (2007)
10.1007/s11229-007-9204-7
The illusion of conscious will
P. Carruthers (2007)
10.1093/brain/awq380
Double-blind clinical trial of thalamic stimulation in patients with Tourette syndrome.
L. Ackermans (2011)
10.1038/2245
Maintaining internal representations: the role of the human superior parietal lobe
D. Wolpert (1998)
10.1016/0006-8993(78)90561-9
An electrical sign of participation of the mesial ‘supplementary’ motor cortex in human voluntary finger movement
L. Deecke (1978)
10.1136/jnnp.2010.221143
Delayed experience of volition in Gilles de la Tourette syndrome
G. Moretto (2011)
10.1038/nrn894
How do you feel? Interoception: the sense of the physiological condition of the body
A. Craig (2002)
10.1038/nn1954
Learning the value of information in an uncertain world
T. Behrens (2007)
10.1093/BRAIN/AWH318
Motor inhibition in patients with Gilles de la Tourette syndrome: functional activation patterns as revealed by EEG coherence.
D. J. Serrien (2005)
10.1038/nature06976
What we can do and what we cannot do with fMRI
N. Logothetis (2008)
10.1017/S0012162203001294
Premonitory sensory phenomena and suppressibility of tics in Tourette syndrome: developmental aspects in children and adolescents.
T. Banaschewski (2003)
10.1093/CERCOR/BHI106
The human parietal operculum. II. Stereotaxic maps and correlation with functional imaging results.
S. Eickhoff (2006)
10.1016/j.tics.2005.04.012
Conscious intention and motor cognition
P. Haggard (2005)
10.1002/hbm.20718
Coordinate‐based activation likelihood estimation meta‐analysis of neuroimaging data: A random‐effects approach based on empirical estimates of spatial uncertainty
S. Eickhoff (2009)
10.1093/BRAIN/AWL050
Neural correlates of tic generation in Tourette syndrome: an event-related functional MRI study.
S. Bohlhalter (2006)
10.1146/ANNUREV.NEURO.26.041002.131022
Pain mechanisms: labeled lines versus convergence in central processing.
A. Craig (2003)
10.1007/s002210050722
On the relation between brain potentials and the awareness of voluntary movements
P. Haggard (1999)
[Behavioral manifestations induced by electric stimulation of the anterior cingulate gyrus in man].
J. Bancaud (1976)
10.1016/j.conb.2008.08.003
Reinforcement learning: The Good, The Bad and The Ugly
P. Dayan (2008)
Visceral Sensory Neuroscience: Interoception
O. Cameron (2001)
10.1523/JNEUROSCI.4286-07.2008
Human Insula Activation Reflects Risk Prediction Errors As Well As Risk
K. Preuschoff (2008)
10.1006/nimg.2002.1131
Meta-Analysis of the Functional Neuroanatomy of Single-Word Reading: Method and Validation
P. Turkeltaub (2002)
10.1152/JN.1999.81.6.2753
Unmyelinated afferents constitute a second system coding tactile stimuli of the human hairy skin.
A. Vallbo (1999)
10.1016/j.neuron.2007.05.016
Human Medial Frontal Cortex Mediates Unconscious Inhibition of Voluntary Action
P. Sumner (2007)
10.1016/J.COGBRAINRES.2004.11.011
Contagious yawning and the brain.
S. Platek (2005)
10.1016/j.cub.2011.02.047
Compensatory Neural Reorganization in Tourette Syndrome
S. Jackson (2011)
10.1016/0013-4694(94)90068-X
Functional anatomy of the human supplementary sensorimotor area: results of extraoperative electrical stimulation.
S. H. Lim (1994)
10.1037/a0013551
Dissociating consciousness from inhibitory control: evidence for unconsciously triggered response inhibition in the stop-signal task.
Simon van Gaal (2009)
Is Yawning A Warning, Neurologically?
S. Thompson (2011)
10.1016/S0022-3999(02)00581-0
Developmental processes and brain imaging studies in Tourette syndrome.
E. Gerard (2003)
10.1136/jnnp.44.8.735
Simple tics in Gilles de la Tourette's syndrome are not prefaced by a normal premovement EEG potential.
J. Obeso (1981)
10.1002/hbm.20711
Intentional inhibition: How the “veto‐area” exerts control
S. Kühn (2009)
10.1016/j.infbeh.2010.03.004
Contagious crying beyond the first days of life.
Elena Geangu (2010)
10.1002/hbm.20333
FMRI activations of amygdala, cingulate cortex, and auditory cortex by infant laughing and crying
K. Sander (2007)
10.1016/j.conb.2009.02.005
General mechanisms for making decisions?
M. Rushworth (2009)
10.1016/j.conb.2010.08.022
Basal ganglia contributions to motor control: a vigorous tutor
R. Turner (2010)
10.1126/SCIENCE.1135926
Damage to the Insula Disrupts Addiction to Cigarette Smoking
N. Naqvi (2007)
10.1371/journal.pbio.0050260
Brain Dynamics Underlying the Nonlinear Threshold for Access to Consciousness
A. Del Cul (2007)
10.1016/S0959-4388(01)00265-3
Computational approaches to motor control
T. Flash (2001)
10.1016/j.neuropsychologia.2008.10.030
Sex differences in the brain response to affective scenes with or without humans
A. Proverbio (2009)
10.1002/mds.10618
Premonitory sensory phenomenon in Tourette's syndrome
C. Kwak (2003)
Psychophysical assessment of the urge-to-cough
Pw Devenport (2002)
10.1177/147470490700500109
Yawning as a Brain Cooling Mechanism: Nasal Breathing and Forehead Cooling Diminish the Incidence of Contagious Yawning
Andrew C Gallup (2007)
10.5860/choice.37-6553
The Feeling of What Happens: Body and Emotion in the Making of Consciousness
A. Damasio (1999)
10.1002/hbm.20705
Two systems of resting state connectivity between the insula and cingulate cortex
Keri S. Taylor (2009)
10.1007/s00429-010-0265-x
Conjoint activity of anterior insular and anterior cingulate cortex: awareness and response
N. Medford (2010)
10.1093/CERCOR/BHL131
Neural signatures of body ownership: a sensory network for bodily self-consciousness.
M. Tsakiris (2007)
10.1016/j.tins.2006.01.001
Recent advances in Tourette syndrome research
R. Albin (2006)
10.1007/978-1-4612-0355-1_15
Time of conscious intention to act in relation to onset of cerebral activity (readiness-potential). The unconscious initiation of a freely voluntary act.
B. Libet (1983)
10.1136/jnnp.61.1.103
Simple motor tics may be preceded by a premotor potential.
B. Karp (1996)
10.1016/0013-4694(73)90149-1
The cingulate gyrus and human behaviour.
J. Talairach (1973)
10.1523/JNEUROSCI.1590-05.2005
Awareness of the Functioning of One's Own Limbs Mediated by the Insular Cortex?
H. Karnath (2005)
10.1016/j.cognition.2008.11.006
Feelings of control: Contingency determines experience of action
James W. Moore (2009)
10.1038/nrn2555
How do you feel — now? The anterior insula and human awareness
A. D. Craig (2009)
10.3758/BF03196307
Links between conscious awareness and response inhibition: Evidence from masked priming
M. Eimer (2002)



This paper is referenced by
10.1038/s41380-020-01007-8
Toward a neurocircuit-based taxonomy to guide treatment of obsessive–compulsive disorder
E. Shephard (2021)
10.1093/braincomms/fcab067
Inhibitory control in children with tic disorder: aberrant fronto-parietal network activity and connectivity
J. Jurgiel (2021)
10.1007/s40474-021-00230-4
Correlates and Clinical Implications of Tic Suppressibility
Keisuke Ueda (2021)
10.1038/s41598-020-60405-8
Impact of cardiac interoception cues and confidence on voluntary decisions to make or withhold action in an intentional inhibition task
C. Rae (2020)
10.1101/2020.01.29.924399
The role of the cingulate cortex in the generation of motor tics and the experience of the premonitory urge-to-tic in Tourette syndrome
S. Jackson (2020)
10.1016/j.cub.2020.04.079
Neurodevelopmental Disorders: Sensing Tourette’s Tics Away
A. Jha (2020)
10.2147/NDT.S274165
Sensory Hypersensitivity Severity and Association with Obsessive-Compulsive Symptoms in Adults with Tic Disorder
David A. Isaacs (2020)
10.3389/fpsyt.2020.00021
Clinical Features That Evoke the Concept of Disinhibition in Tourette Syndrome
Lille Kurvits (2020)
10.1016/j.cortex.2019.12.021
The role of the insula in the generation of motor tics and the experience of the premonitory urge-to-tic in Tourette syndrome
S. Jackson (2020)
10.1002/hbm.24898
The buildup of an urge in obsessive–compulsive disorder: Behavioral and neuroimaging correlates
Emily R. Stern (2020)
10.1111/jsr.13127
The urge to move: From restless legs syndrome to impulse control disorders in Parkinson’s disease
A. Marques (2020)
10.3389/fpsyg.2020.603385
Compassion As an Intervention to Attune to Universal Suffering of Self and Others in Conflicts: A Translational Framework
S. S. Ho (2020)
10.1016/j.cortex.2020.04.014
A feasibility study for somatomotor cortical mapping in Tourette syndrome using neuronavigated transcranial magnetic stimulation
H. Sigurdsson (2020)
10.1016/j.encep.2019.11.003
Stimulation therapeutic approaches to better understand Obsessive Compulsive Disorder: The issue of 'where' to treat.
R. Maatoug (2020)
10.1101/2020.05.01.071837
Examining the neural antecedents of tics in Tourette syndrome using electroencephalography
Barbara Morera Maiquez (2020)
10.1093/braincomms/fcaa199
Amplified engagement of prefrontal cortex during control of voluntary action in Tourette syndrome
C. Rae (2020)
10.1016/j.jpsychires.2020.01.019
The functional connectivity profile of tics and obsessive-compulsive symptoms in Tourette Syndrome.
Tracy Bhikram (2020)
10.1016/b978-0-444-64196-0.00016-9
Cingulate impairments in ADHD: Comorbidities, connections, and treatment.
B. Vogt (2019)
10.3389/fpsyt.2019.00029
A Bayesian Account of the Sensory-Motor Interactions Underlying Symptoms of Tourette Syndrome
C. Rae (2019)
10.1093/brain/awy306
Impaired forward model updating in young adults with Tourette syndrome
S. Kim (2019)
10.7916/D8-GKH0-CG55
Psychophysical Evaluation of Descriptors and Tools for Measurement of Urge-to-Cough Sensation in Healthy Young Adults (HYA)
A. Rajappa (2019)
10.1016/j.cortex.2019.07.010
The urge to blink in Tourette syndrome
H. Botteron (2019)
10.1162/jocn_a_01423
The Functional Role of Response Suppression during an Urge to Relieve Pain
Kelsey K. Sundby (2019)
10.1016/j.neuron.2019.09.024
The Meaning of Behavior: Discriminating Reflex and Volition in the Brain
B. Balleine (2019)
10.1016/j.parkreldis.2019.02.005
Tics and stereotypies: A comparative clinical review.
D. Martino (2019)
10.1101/477372
The urge to blink in Tourette syndrome
H. Botteron (2019)
10.1016/j.cortex.2019.06.016
Help or hurt? How attention modulates tics under different conditions
Katja Herrmann (2019)
10.1016/j.jpsychires.2018.11.018
Functional neural mechanisms of sensory phenomena in obsessive-compulsive disorder.
Carina M Brown (2019)
10.1111/ner.12874
A Comprehensive Review of Dorsomedial Prefrontal Cortex rTMS Utilizing a Double Cone Coil
Peter M. Kreuzer (2018)
10.1093/brain/awy254
Face perception enhances insula and motor network reactivity in Tourette syndrome
C. Rae (2018)
10.1016/j.concog.2018.09.011
Subjective embodiment during the rubber hand illusion predicts severity of premonitory sensations and tics in Tourette Syndrome
C. Rae (2018)
10.1111/ner.12875
Lack of Target Engagement Following Low‐Frequency Deep Transcranial Magnetic Stimulation of the Anterior Insula
P. Spagnolo (2018)
See more
Semantic Scholar Logo Some data provided by SemanticScholar