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On The Functional Anatomy Of The Urge-for-action
S. Jackson, A. Parkinson, S. Kim, Martin Schüermann, S. Eickhoff
Published 2011 · Psychology, Medicine
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Several common neuropsychiatric disorders (e.g., obsessive-compulsive disorder, Tourette syndrome (TS), autistic spectrum disorder) are associated with unpleasant bodily sensations that are perceived as an urge for action. Similarly, many of our everyday behaviors are also characterized by bodily sensations that we experience as urges for action. Where do these urges originate? In this paper, we consider the nature and the functional anatomy of “urges-for-action,” both in the context of everyday behaviors such as yawning, swallowing, and micturition, and in relation to clinical disorders in which the urge-for-action is considered pathological and substantially interferes with activities of daily living (e.g., TS). We review previous frameworks for thinking about behavioral urges and demonstrate that there is considerable overlap between the functional anatomy of urges associated with everyday behaviors such as swallowing, yawning, and micturition, and those urges associated with the generation of tics in TS. Specifically, we show that the limbic sensory and motor regions––insula and mid-cingulate cortex––are common to all of these behaviors, and we argue that this “motivation-for-action” network should be considered distinct from an “intentional action” network, associated with regions of premotor and parietal cortex, which may be responsible for the perception of “willed intention” during the execution of goal-directed actions.
This paper references
Maintaining internal representations: the role of the human superior parietal lobe
D. Wolpert (1998)
Hearing others’ pain: neural activity related to empathy
S. Lang (2011)
Altered awareness of voluntary action after damage to the parietal cortex
A. Sirigu (2004)
Neural correlates of tic generation in Tourette syndrome: an event-related functional MRI study.
S. Bohlhalter (2006)
A Neural Substrate of Prediction and Reward
W. Schultz (1997)
Glucose-sensing neurons of the hypothalamus
D. Burdakov (2005)
Contagious yawning and the brain.
S. Platek (2005)
The hidden island of addiction: the insula
N. Naqvi (2009)
On the relation between brain potentials and the awareness of voluntary movements
P. Haggard (1999)
Modulation of somatosensory perception by motor intention
A. Parkinson (2011)
Habits, rituals, and the evaluative brain.
A. Graybiel (2008)
Urge-to-Cough: What Can It Teach Us About Cough?
P. Davenport (2007)
Psychophysical assessment of the urge-to-cough
Pw Devenport (2002)
Sensory stimulation activates both motor and sensory components of the swallowing system
Soren Y. Lowell (2008)
Time of conscious intention to act in relation to onset of cerebral activity (readiness-potential). The unconscious initiation of a freely voluntary act.
B. Libet (1983)
Premonitory sensory phenomena and suppressibility of tics in Tourette syndrome: developmental aspects in children and adolescents.
T. Banaschewski (2003)
Feelings of control: Contingency determines experience of action
J. Moore (2009)
Premonitory urges in Tourette's syndrome.
J. Leckman (1993)
Cerebral mechanisms of word masking and unconscious repetition priming
S. Dehaene (2001)
Delayed experience of volition in Gilles de la Tourette syndrome
G. Moretto (2011)
Is Yawning A Warning, Neurologically?
Simon B. N. Thompson (2011)
The Feeling of What Happens: Body and Emotion in the Making of Consciousness
A. Damasio (1999)
What we can do and what we cannot do with fMRI
N. Logothetis (2008)
Human Medial Frontal Cortex Mediates Unconscious Inhibition of Voluntary Action
P. Sumner (2007)
Double-blind clinical trial of thalamic stimulation in patients with Tourette syndrome.
L. Ackermans (2011)
An electrical sign of participation of the mesial ‘supplementary’ motor cortex in human voluntary finger movement
L. Deecke (1978)
Parietal updating of limb posture: An event-related fMRI study
Asa Pellijeff (2006)
Brain Dynamics Underlying the Nonlinear Threshold for Access to Consciousness
A. Del Cul (2007)
Compensatory Neural Reorganization in Tourette Syndrome
S. Jackson (2011)
Functional anatomy of the human supplementary sensorimotor area: results of extraoperative electrical stimulation.
S. H. Lim (1994)
Clinical effects of insular damage in humans
Agustín Ibáñez (2010)
Unmyelinated tactile afferents signal touch and project to insular cortex
H. Olausson (2002)
How do you feel? Interoception: the sense of the physiological condition of the body
A. D. Craig (2002)
Awareness of the Functioning of One's Own Limbs Mediated by the Insular Cortex?
H. Karnath (2005)
Computational approaches to motor control
T. Flash (2001)
Altered motor network recruitment during finger tapping in boys with tourette syndrome
V. Roessner (2012)
Two systems of resting state connectivity between the insula and cingulate cortex
Keri S. Taylor (2009)
Yawning as a Brain Cooling Mechanism: Nasal Breathing and Forehead Cooling Diminish the Incidence of Contagious Yawning
Andrew C Gallup (2007)
Abnormalities in the awareness of action
Sarah-Jayne Blakemore (2002)
Action sets and decisions in the medial frontal cortex
M. Rushworth (2004)
Conjoint activity of anterior insular and anterior cingulate cortex: awareness and response
N. Medford (2010)
Tight Link Between Our Sense of Limb Ownership and Self-Awareness of Actions
B. Baier (2008)
Review: The Feeling of What Happens: Body, Emotion and the Making of Consciousness
Robert W. Kentridge (2000)
The Neural Basis of Inhibition in Cognitive Control
A. Aron (2007)
My body in the brain: A neurocognitive model of body-ownership
M. Tsakiris (2010)
Contagious crying beyond the first days of life.
Elena Geangu (2010)
Recent advances in Tourette syndrome research
R. Albin (2006)
Imaging the premotor areas
N. Picard (2001)
Patient perception of tics and other movement disorders
A. Lang (1991)
Dissociating consciousness from inhibitory control: evidence for unconsciously triggered response inhibition in the stop-signal task.
Simon van Gaal (2009)
Basal ganglia contributions to motor control: a vigorous tutor
R. Turner (2010)
Sensory experiences of Gilles de la Tourette syndrome.
J. Bliss (1980)
How do you feel — now? The anterior insula and human awareness
A. D. Craig (2009)
[Behavioral manifestations induced by electric stimulation of the anterior cingulate gyrus in man].
J. Bancaud (1976)
Examining the impact of distraction on tic suppression in children and adolescents with Tourette syndrome.
Christine A. Conelea (2008)
Premonitory sensory phenomenon in Tourette's syndrome
C. Kwak (2003)
Neural signatures of body ownership: a sensory network for bodily self-consciousness.
M. Tsakiris (2007)
Developmental processes and brain imaging studies in Tourette syndrome.
E. Gerard (2003)
General mechanisms for making decisions?
M. Rushworth (2009)
Simple motor tics may be preceded by a premotor potential.
B. Karp (1996)
The insula; further observations on its function.
W. Penfield (1955)
Sex differences in the brain response to affective scenes with or without humans
A. Proverbio (2009)
Coordinate‐based activation likelihood estimation meta‐analysis of neuroimaging data: A random‐effects approach based on empirical estimates of spatial uncertainty
S. Eickhoff (2009)
Computational principles of movement neuroscience
D. Wolpert (2000)
Altered modulation of intracortical excitability during movement preparation in Gilles de la Tourette syndrome.
K-F Heise (2010)
K. Müller-Vahl (2009)
FMRI activations of amygdala, cingulate cortex, and auditory cortex by infant laughing and crying
K. Sander (2007)
Simple tics in Gilles de la Tourette's syndrome are not prefaced by a normal premovement EEG potential.
J. Obeso (1981)
Reinforcement learning: The Good, The Bad and The Ugly
P. Dayan (2008)
A parietal-premotor network for movement intention and motor awareness
M. Desmurget (2009)
Parietal cortex coding of limb posture: In search of the body-schema
A. Parkinson (2010)
The cingulate gyrus and human behaviour.
J. Talairach (1973)
Visceral Sensory Neuroscience: Interoception
O. Cameron (2001)
Human Insula Activation Reflects Risk Prediction Errors As Well As Risk
K. Preuschoff (2008)
Bereitschaftspotential in tic disorders: a preliminary observation.
H. Duggal (2002)
The human parietal operculum. II. Stereotaxic maps and correlation with functional imaging results.
S. Eickhoff (2006)
Conscious intention and motor cognition
P. Haggard (2005)
Unmyelinated afferents constitute a second system coding tactile stimuli of the human hairy skin.
A. Vallbo (1999)
Intentional inhibition: How the “veto‐area” exerts control
S. Kühn (2009)
Meta-Analysis of the Functional Neuroanatomy of Single-Word Reading: Method and Validation
P. Turkeltaub (2002)
Damage to the Insula Disrupts Addiction to Cigarette Smoking
N. Naqvi (2007)
Representation of pain and somatic sensation in the human insula: a study of responses to direct electrical cortical stimulation.
K. Ostrowsky (2002)
Yearning to yawn: the neural basis of contagious yawning
M. Schürmann (2005)
Links between conscious awareness and response inhibition: Evidence from masked priming
M. Eimer (2002)
Pain mechanisms: labeled lines versus convergence in central processing.
A. Craig (2003)
The illusion of conscious will
P. Carruthers (2007)
Learning the value of information in an uncertain world
T. Behrens (2007)
Motor inhibition in patients with Gilles de la Tourette syndrome: functional activation patterns as revealed by EEG coherence.
D. J. Serrien (2005)
Circuitry and functional aspects of the insular lobe in primates including humans
J. Augustine (1996)
This paper is referenced by
Premonitory urges are associated with decreased grey matter thickness within the insula and sensorimotor cortex in young people with Tourette syndrome
A. Draper (2016)
The neural antecedents to voluntary action: A conceptual analysis
P. Nachev (2014)
Cognitive control over motor output in Tourette syndrome
J. Jung (2013)
Tics and stereotypies: A comparative clinical review.
D. Martino (2019)
Immune-mediated animal models of Tourette syndrome
M. Hornig (2013)
Subjective embodiment during the rubber hand illusion predicts severity of premonitory sensations and tics in Tourette Syndrome
C. Rae (2018)
The role of the insula in the generation of motor tics and the experience of the premonitory urge-to-tic in Tourette syndrome
S. Jackson (2020)
TITLE : Anterior cingulate implant for alcohol addiction : case report
D. Ridder ()
The Functional Role of Response Suppression during an Urge to Relieve Pain
Kelsey K. Sundby (2019)
Functional neural mechanisms of sensory phenomena in obsessive-compulsive disorder.
Carina M Brown (2019)
Neurology of volition
S. Kranick (2013)
Neural basis of contagious itch and why some people are more prone to it
H. Holle (2012)
Intrusive Thoughts Elicited by Direct Electrical Stimulation during Stereo-Electroencephalography
I. Popa (2016)
Role of the right dorsal anterior insula in the urge to tic in tourette syndrome
S. Tinaz (2015)
Investigating interoception and body awareness in adults with and without autism spectrum disorder
L. Fiene (2015)
Pathophysiology-Based Neuromodulation for Addictions
D. Ridder (2016)
Independent component analysis of functional networks for response inhibition: Inter‐subject variation in stop signal reaction time
Shenmin Zhang (2015)
Neural Plasticity in Functional and Anatomical MRI Studies of Children with Tourette Syndrome
Heike Eichele (2013)
Tics and Tourette's: update on pathophysiology and tic control.
C. Ganos (2016)
Impact of cardiac interoception cues and confidence on voluntary decisions to make or withhold action in an intentional inhibition task
C. Rae (2020)
Cingulate impairments in ADHD: Comorbidities, connections, and treatment.
B. Vogt (2019)
Neurodevelopmental Disorders: Sensing Tourette’s Tics Away
A. Jha (2020)
The Psychosocial Impact of Tic Disorders: Nature and Intervention
David C. Houghton (2016)
Development of a measure of cognitions and beliefs in trichotillomania
Imogen C Rehm (2016)
Centrality of prefrontal and motor preparation cortices to Tourette Syndrome revealed by meta-analysis of task-based neuroimaging studies
Liliana Polyanska (2017)
Psychophysical Evaluation of Descriptors and Tools for Measurement of Urge-to-Cough Sensation in Healthy Young Adults (HYA)
A. Rajappa (2019)
Neuroimaging Applications in Tourette's Syndrome.
D. Martino (2018)
Impaired forward model updating in young adults with Tourette syndrome
S. Kim (2019)
Premonitory Urges and Sensorimotor Processing in Tourette Syndrome
S. Rajagopal (2013)
Neural Circuitry of Interoception: New Insights into Anxiety and Obsessive-Compulsive Disorders
Emily R. Stern (2014)
Quantitative Sensory Testing in adults with Tourette syndrome.
Odette Schunke (2016)
Examining the neural antecedents of tics in Tourette syndrome using electroencephalography
Barbara Morera Maiquez (2020)See more