Online citations, reference lists, and bibliographies.
Please confirm you are human
(Sign Up for free to never see this)
← Back to Search

Influence Of Temperature Upon Contractile Activation And Isometric Force Production In Mechanically Skinned Muscle Fibers Of The Frog

R. Godt, B. Lindley
Published 1982 · Chemistry, Medicine

Save to my Library
Download PDF
Analyze on Scholarcy
Share
Increasing temperature (4-22 degrees C) increases the Ca2+ concentration required for activation of mechanically skinned frog muscle fibers. The pCa required for 50% maximal force (pCa50) was inversely proportional to absolute temperature. Assuming that relative force is directly related to fractional occupancy of the Ca2+-binding sites on troponin that regulate force, the shift was consistent with a Gibbs free energy change of binding (delta G) of about -7.8 kcal/mol. This is close to the delta G for Ca2+ binding to the calcium-specific sites on troponin C reported by others. Decreasing Mg2+ from 1 mM to 60 microM shifts the force-pCa curves at either 4 or 22 degrees C to higher pCa, but the shift of pCa50 with temperature over this range (0.4 log units) was the same at low and high Mg2+. Maximal force increased with temperature for the entire range 4-22 degrees C with a Q10 of 1.41, and over the restricted range 4-15 degrees C with a Q10 of 1.20. From the dual effects of temperature on Ca2+ activation and maximal force, one would expect that force would respond differently to temperature change at high or low Ca2+. At high Ca2+, a temperature increase will lead to an increased force. However, at low to intermediate Ca2+ levels (below the intersection of the force-pCa curves for the initial and final temperatures), steady state force should decrease with increasing temperature. The inverse responses should occur with a decrease in temperature. These responses are observed when temperature is changed by rapid solution exchange.
This paper references
10.1016/S0065-3233(08)60190-4
LINKED FUNCTIONS AND RECIPROCAL EFFECTS IN HEMOGLOBIN: A SECOND LOOK.
J. Wyman (1964)
10.1021/ja00956a008
Thermodynamic quantities associated with the interaction of adenosine triphosphate with metal ions.
M. Khan (1966)
Komplexone . XXXVI . Reaktionsenthalpi e and entropie bei der Metallkomplexe der hohern EDTA-Homologen
Anderegg (1964)
Komplexone . XXXVI . Reaktionsenthalpi e and entropie bei der Metallkomplexe der hohern EDTAHomologen
G. ANDEREGG (1964)
Th e role of actin in modulating Ca2' binding to troponin
J D Potter (1982)
10.1038/233533A0
Proposed Mechanism of Force Generation in Striated Muscle
A. Huxley (1971)
10.1152/PHYSREV.1972.52.1.129
Dynamic properties of mammalian skeletal muscles.
R. Close (1972)
10.1021/BI00889A005
THE STABILITY CONSTANTS OF METAL-ADENINE NUCLEOTIDE COMPLEXES.
W. O'Sullivan (1964)
Characterization of the Effects of Mg 2 + on Ca 2 +-and Sr 2 +-Activated Tension Generation of Skinned Skeletal Muscle Fibers
S. B. Donaldson (1975)
GODT AND LINDLEY Temperature Effects on Cat+-activated Force
10.1016/0005-2728(82)90261-4
Parallel measurements of bound calcium and force in glycerinated rabbit psoas muscle fibers.
F. Fuchs (1982)
10.1038/260440A0
Development of difference between red and white muscles in sensitivity to Ca2+ in the rabbit from embryo to adult
W. G. Kerrick (1976)
10.1113/jphysiol.1978.sp012188
Calcium and strontium concentration changes within skinned muscle preparations following a change in the external bathing solution.
D. Moisescu (1978)
The effect of pH on Ca 2+ -activated force in frog skeletal muscle fibers. Pflu'gers Arch. Gesamte PhysioL Menschen Tiere
S P Robertson (1979)
A study on rapid cooling contracture from the viewpoint of excitation-contraction coupling
T Sakai (1974)
The effect of pH on Ca 2+ -activated force in frog skeletal muscle fibers. Pflu'gers Arch
S P Robertson (1979)
10.1152/AJPCELL.1977.233.5.C127
Regulation of tension in skinned muscle fibers: effect of high concentrations of Mg-ATP.
M. Orentlicher (1977)
10.1101/SQB.1973.037.01.061
Length Dependence of Activation of Skinned Muscle Fibers by Calcium
M. Endo (1973)
10.1016/0005-2736(80)90205-9
Neutral carrier ion-selective microelectrodes for measurement of intracellular free calcium.
R. Tsien (1980)
10.1021/BI00885A015
Alkali Metal Binding by Ethylenediaminetetraacetate, Adenosine 5'-Triphosphate, and Pyrophosphate*
J. Botts (1965)
10.1113/jphysiol.1981.sp013825
Calcium‐activated force responses in fast‐ and slow‐twitch skinned muscle fibres of the rat at different temperatures.
D. Stephenson (1981)
10.1016/s0021-9258(19)41347-1
The calcium and magnesium binding sites on troponin and their role in the regulation of myofibrillar adenosine triphosphatase.
J. Potter (1975)
10.1007/springerreference_36688
THE SARCOPLASMIC RETICULUM
K. Porter (1961)
Cat+ -and Sr2+-activated tension generation of skinned skeletal muscle fibers
10.1085/JGP.63.4.415
Effect of External Calcium and of Temperature on Contraction in Snake Muscle Fibers
H. Washio (1974)
Post - denervation contractile properties of rat muscle
W. BERBERICH (1981)
Thermodynamics of ion association . XII . EGTA complexes with divalent metal ions
Boyd (1965)
Thermodynamics of ion association . XII . EGTA complexes with divalent metal ions
S Boyd (1965)
10.1016/0005-2728(76)90091-8
Ca2+ dependence of tension and ADP production in segments of chemically skinned muscle fibers.
R. M. Levy (1976)
10.1085/JGP.63.6.722
Calcium-Activated Tension of Skinned Muscle Fibers of the Frog
R. Godt (1974)
10.1126/SCIENCE.841325
Aequorin luminescence: relation of light emission to calcium concentration--a calcium-independent component.
D. G. Allen (1977)
10.1113/jphysiol.1977.sp011911
Tension responses to sudden length change in stimulated frog muscle fibres near slack length
L. Ford (1977)
Isometric contractile properties and instantaneous stiffness of amphibian skeletal muscle in the temperature range from 0°C to 20°C . Can
B H Bressler (1981)
10.1016/0005-2728(79)90170-1
Sarcomere length effects on the Sr2+- and Ca2+-activation curves in skinned frog muscle fibres.
D. Moisescu (1979)
Isometric contractile properties and instantaneous stiffness of amphibian skeletal muscle in the temperature range from 0 ° C to 20 ° C . Can
B H Bressler (1981)
Thermodynami c studies of the formation and ionization of the magnesium (II) complexes of ADP and ATP over the pH range
R C Phillips (1966)
10.1021/cen-v028n018.p1517
The Physical Chemistry of Electrolytic Solutions
H. Harned (1963)
Proceedings: Effect of temperature on the pCa-tension relation of skinned ventricular muscle of the cat.
P. Brandt (1976)
10.1113/jphysiol.1972.sp009858
The effect of low temperature on the excitation‐contraction coupling phenomena of frog single muscle fibres
C. Caputo (1972)
A study on rapid cooling contracture from the viewpoint of excitation-contraction coupling
Sakai (1974)
10.1111/J.1748-1716.1950.TB00744.X
Tensile force in total striated muscle, isolated fibre and sarcolemma.
C. Casella (1950)
10.1016/0014-4886(77)90161-3
Guinea pig soleus and extensor digitorum longus: A study on single-skinned fibers
A. Takagi (1977)
Komplexone. XXIX . Eln grosser Chelateffekt besonderer Art . Helv. Chim. Acta
Schwartzenbach (1957)
The effect of pH on Ca2+-activated force in frog skeletal muscle fibers
W. G . L. KERRICK (1979)
Komplexone . XXXVI . Reaktionsenthalpi e and entropie bei der Metallkomplexe der hohern EDTA-Homologen
G Anderegg (1964)
Calculator programs for computing the composition of the solutions containing multiple metals and ligands used for experiments in skinned muscle cells.
A. Fabiato (1979)
Proportionale Aktivierung von ATPase-Aktivitat and Kontraktionsspannung durch Calciumionen in isolierten contractilen Strukturen Verschiedener
M. SCHADLER (1967)
Critical Stability Constants. Volume 1: Amino Acids
A. E. MARTELL (1974)
10.1021/BI00866A011
Hydrogen ion buffers for biological research.
W. J. Ferguson (1980)
10.1139/Y81-082
Isometric contractile properties and instantaneous stiffness of amphibian skeletal muscle in the temperature range from 0 to 20 degrees C.
B. Bressler (1981)
10.1113/jphysiol.1978.sp012273
Calcium transients in isolated amphibian skeletal muscle fibres: detection with aequorin.
J. R. Blinks (1978)
10.1017/S0033583500001190
Control of muscle contraction.
S. Ebashi (1969)
10.1113/jphysiol.1979.sp012972
Rabbit diaphragm: two types of fibres determined by calcium strontium activation and protein content.
P. E. Hoar (1979)
The sarcoplasmic reticulum: Transport and energy transduction
L. Meis (1981)
10.1016/S0006-3495(78)85367-3
Contractile deactivation by rapid, microwave-induced temperature jumps.
B. Lindley (1978)
J. Am . Chem. Soc
10.1016/s0021-9258(18)50787-0
A fluorescence stopped flow analysis of Ca2+ exchange with troponin C.
J. D. Johnson (1979)
Post-denervation contractile properties of rat muscle
Kirby (1981)
Forc e measurements in skinned muscle fibers
D C Hellam (1969)
Post-denervation contractile properties of rat muscle
A. C. KIRBY (1981)
Th e purification of cardiac myofibrils with Triton X-100
R J Solaro (1971)
10.1021/JA01592A009
The Apparent Stability Constants of Ionic Complexes of Various Adenosine Phosphates with Divalent Cations1,2
R. M. Smith (1956)
10.1113/jphysiol.1981.sp014004
A comparative study of charge movement in rat and frog skeletal muscle fibres.
S. Hollingworth (1981)
10.1113/jphysiol.1977.sp011972
Effect of changing the composition of the bathing solution upon the isometric tension—pCa relationship in bundles of crustacean myofibrils
C. Ashley (1977)
Voltage-dependen t charge movement in skeletal muscle : a possible step in excitation-contraction coupling
M F Schneider (1973)
Forc e measurements in skinned muscle fibers
Hellam (1969)
Receivedforpublication 13 April 1981 and in revised form 18
(1982)
This work was supported by grants AM 25851 (REG) and HL 19848 (BDL) from the U .S . Public Health Service
Effect of temperature on the pCa-tension relation of skinned ventricular muscle of the cat .J
P. W. BRANDT (1976)
10.1021/JA00964A002
Thermodynamic studies of the formation and ionization of the magnesium(II) complexes of ADP and ATP over the pH range 5 to 9.
R. Phillips (1966)
10.1016/s0021-9258(17)40577-1
Thermodynamics of Ca2+ binding to troponin-C.
J. Potter (1977)



This paper is referenced by
10.3389/fphys.2017.00840
Altered Right Ventricular Mechanical Properties Are Afterload Dependent in a Rodent Model of Bronchopulmonary Dysplasia
J. R. Patel (2017)
10.1111/j.1469-7793.2000.t01-1-00541.x
Attenuation of length dependence of calcium activation in myofilaments of transgenic mouse hearts expressing slow skeletal troponin I
G. Arteaga (2000)
MODELING TEMPERATURE DEPENDENT DYNAMIC CONTRACTILE PROPERTIES IN HUMAN SKELETAL MUSCLE FIBERS USING CROSSBRIDGE MODELS
Sampath K Gollapudi (2011)
10.1007/s003600050173
Effects of pH and temperature on myocardial calcium-activation in Pterygoplichthys (catfish)
K. Meadows (1998)
10.1152/ajpheart.1999.276.5.H1511
Aging-dependent depression in the kinetics of force development in rat skinned myocardium.
D. Fitzsimons (1999)
10.1016/S0304-3940(00)01001-6
Mechanisms underlying the M-current block by barium in bullfrog sympathetic neurons
S. Kotani (2000)
10.1016/0301-4622(91)80007-E
Time-resolved synchrotron X-ray diffraction studies of a single frog skeletal muscle fiber. Time courses of intensity changes of the equatorial reflections and intracellular Ca2+ transients.
M. Konishi (1991)
10.1152/ajpregu.90564.2008
Human vastus lateralis and soleus muscles display divergent cellular contractile properties.
N. Luden (2008)
10.1152/ajpheart.00374.2014
Sex-dependent, zinc-induced dephosphorylation of phospholamban by tissue-nonspecific alkaline phosphatase in the cardiac sarcomere.
Y. Wang (2014)
10.1074/jbc.M114.562231
Magnesium Modulates Actin Binding and ADP Release in Myosin Motors*
Anja M. Swenson (2014)
10.1007/BF00584534
Evolutionary adaptation of muscle power output to environmental temperature: force-velocity characteristics of skinned fibres isolated from antarctic, temperate and tropical marine fish
I. Johnston (2004)
10.1007/978-3-030-50476-2_5
Bioinspired Sensors and Actuators Based on Stimuli-Responsive Hydrogels for Underwater Soft Robotics
Chiao‐Yueh Lo (2021)
10.1113/jphysiol.1997.sp022044
Contrasting effects of intracellular redox couples on the regulation of maxi‐K channels in isolated myocytes from rabbit pulmonary artery.
D. Thuringer (1997)
Development in Single Adult Cardiac Myocytes-Activated Tension 2 + Effects of Myosin Heavy Chain Isoform Switching on Ca
J. Metzger (1999)
10.1152/ajpheart.1997.273.5.H2428
The Frank-Starling mechanism is not mediated by changes in rate of cross-bridge detachment.
T. Wannenburg (1997)
10.1016/j.bpj.2010.06.047
The influence of myosin converter and relay domains on cross-bridge kinetics of Drosophila indirect flight muscle.
Chaoxing Yang (2010)
10.1085/JGP.93.3.429
Block of contracture in skinned frog skeletal muscle fibers by calcium antagonists
M. Fill (1989)
Thermal dependence of maximum Ca2+-activated force in skinned muscle fibres of the toad Bufo marinus acclimated at different temperatures.
B. Rees (1987)
10.1074/JBC.M508430200
The Essential Light Chain N-terminal Extension Alters Force and Fiber Kinetics in Mouse Cardiac Muscle*
M. S. Miller (2005)
10.1161/CIRCHEARTFAILURE.108.802298
Effects of Cardiac Myosin Isoform Variation on Myofilament Function and Crossbridge Kinetics in Transgenic Rabbits
T. Suzuki (2009)
10.1111/j.1469-7793.2001.0583c.xd
Cardiac troponin T mutations: correlation between the type of mutation and the nature of myofilament dysfunction in transgenic mice
D. E. Montgomery (2001)
10.1007/BF00240028
E-1020, a water soluble imidazopyridine, has direct effects on Ca2+-dependent force and ATP hydrolysis of canine and bovine cardiac myofilaments
F. M. Powers (2004)
10.1152/JAPPL.2001.90.4.1196
Effect of unilateral denervation on maximum specific force in rat diaphragm muscle fibers.
P. Geiger (2001)
10.1152/JAPPL.1999.87.5.1894
Force-calcium relationship depends on myosin heavy chain and troponin isoforms in rat diaphragm muscle fibers.
P. Geiger (1999)
10.1016/S0006-3495(98)77793-8
Phosphorylation of myosin regulatory light chain eliminates force-dependent changes in relaxation rates in skeletal muscle.
J. R. Patel (1998)
10.1007/BF02505757
Temperature dependence of embryonic cardiac gap junction conductance and channel kinetics
Y. Chen (1993)
10.1016/j.bpj.2011.08.047
Roles for cardiac MyBP-C in maintaining myofilament lattice rigidity and prolonging myosin cross-bridge lifetime.
B. Palmer (2011)
10.1016/j.yjmcc.2012.12.022
Elevated rates of force development and MgATP binding in F764L and S532P myosin mutations causing dilated cardiomyopathy.
B. Palmer (2013)
Specific force in human single muscle fibres with specific reference to ageing
Michaeljohn Kalakoutis (2017)
10.1152/JAPPL.2000.89.2.695
Maximum specific force depends on myosin heavy chain content in rat diaphragm muscle fibers.
P. Geiger (2000)
10.1007/BF01964791
The effects of temperature on ATPase activity and force generation in skinned muscle fibers from the Pacific blue marlin (Makaira nigricans)
J. Altringham (2005)
10.1152/AJPREGU.00376.2006
Myofilament response to Ca2+ and Na+/H+ exchanger activity in sex hormone-related protection of cardiac myocytes from deactivation in hypercapnic acidosis.
Tepmanas Bupha-Intr (2007)
See more
Semantic Scholar Logo Some data provided by SemanticScholar