Online citations, reference lists, and bibliographies.
← Back to Search

Novel Regulation Of Lipoprotein Lipase Activity In Rat Brown Adipose Tissue: Effects Of Fasting And Caloric Restriction During Refeeding.

S. Fried, J. Hill, M. Nickel, M. Digirolamo
Published 1983 · Biology, Medicine

Cite This
Download PDF
Analyze on Scholarcy
Share
We studied the effects of a 3-day fast and 20 days of refeeding on lipoprotein lipase activity (LPL) in the interscapular brown adipose tissue (BAT) of sexually mature male rats. Rats were refed either ad libitum or restricted quantities (75 or 50% of normal ad libitum food intake). BAT-LPL, expressed on a per depot basis, decreased with fasting and returned to control values by day 3 of refeeding ad libitum. In contrast, refeeding restricted quantities for 5 to 20 days limited regain of body weight and increased BAT-LPL significantly above the values observed in rats refed ad libitum. These adaptations in BAT-LPL activity differ markedly from those observed in rat white adipose tissue or heart muscle and may serve to increase the supply of fatty acids from circulating lipoproteins for BAT metabolic needs and maintenance of thermogenesis during undernutrition.
This paper references
10.1016/0014-5793(79)80706-1
Purification and characterization of lipoprotein lipase from rat brown fat
D. Guerrier (1979)
10.1016/0026-0495(81)90046-9
Onset and development of hypertriglyceridemia in the Zucker rat (fa/fa).
A. Boulangé (1981)
10.1055/S-2007-999207
Adipose, muscle and lung tissue lipoprotein lipase activities in young streptozotocin treated rats.
R. Rauramaa (1980)
10.1042/BJ1740447
Developmental changes in the activity of lipoprotein lipase (clearing-factor lipase) in rat lung, cardiac muscle, skeletal muscle and brown adipose tissue.
A. Cryer (1978)
10.1055/S-0028-1093708
The lipoprotein lipase activity of brown adipose tissue during early post-natal development of the normal and hypothyroid rat.
P. Hémon (1975)
10.1152/AJPLEGACY.1971.220.6.1852
Response of lipoprotein lipase in various tissues to cold exposure.
M. Radomski (1971)
10.1038/281031A0
A role for brown adipose tissue in diet-induced thermogenesis
N. Rothwell (1979)
10.1139/Y78-015
Nonshivering thermogenesis in the rat. II. Measurements of blood flow with microspheres point to brown adipose tissue as the dominant site of the calorigenesis induced by noradrenaline.
D. Foster (1978)
Development and testing of an automated food dispenser for small rodents.
M. Digirolamo (1981)
A simple method for the isolation and purification of total lipides from animal tissues.
J. Folch (1957)
10.1111/J.1432-1033.1969.TB00759.X
Oxidative phosphorylation and compartmentation of fatty acid metabolism in brown fat mitochondria.
K. Hittelman (1969)
10.1093/JN/113.9.1861
Prolonged effects of fasting-refeeding on rat adipose tissue lipoprotein lipase activity: influence of caloric restriction during refeeding.
S. Fried (1983)
10.1016/0306-4565(78)90080-3
Biochemical aspects of nonshivering thermogenesis
J. Himms-Hagen (1978)
10.1146/ANNUREV.BI.49.070180.003315
Lipolytic enzymes and plasma lipoprotein metabolism.
P. Nilsson-ehle (1980)
10.1042/CS0500213
Effect of nutritional status on rat adipose tissue, muscle and post-heparin plasma clearing factor lipase activities: their relationship to triglyceride fatty acid uptake by fat-cells and to plasma insulin concentrations.
A. Cryer (1976)
Lipoprotein lipase activities in tissues of normal and genetically obese (ob-ob) mice.
E. Rath (1974)
10.3181/00379727-169-41351
Palmitate Metabolism and Norepinephrine Sensitivity in Brown Adipose, Liver, and White Adipose Tissues of Zucker Rats 1
T. R. Kasser (1982)
10.1016/0005-2760(81)90098-9
The utilization of ketone bodies by the interscapular brown adipose tissue of the rat.
L. Agius (1981)
10.1152/AJPENDO.1980.238.6.E511
Importance of muscle lipoprotein lipase in rats during suckling.
E. Planche (1980)



This paper is referenced by
10.1042/BSR20080089
Oleoyl-oestrone inhibits lipogenic, but maintains thermogenic, gene expression of brown adipose tissue in overweight rats.
M. M. Romero (2009)
10.1016/j.jnutbio.2015.01.010
Short-term food restriction followed by controlled refeeding promotes gorging behavior, enhances fat deposition, and diminishes insulin sensitivity in mice.
Kara L. Kliewer (2015)
10.1210/ENDO.138.2.4908
Immunohistochemical localization of leptin and uncoupling protein in white and brown adipose tissue.
S. Cinti (1997)
10.1016/j.arr.2009.11.004
Perspective: Does brown fat protect against diseases of aging?
M. Mattson (2010)
10.3109/13813458909104544
Alterations of energy metabolism induced by hexadecane in mice.
J. Huguet (1989)
10.1006/BBRC.2000.3864
Disruption of klotho gene causes an abnormal energy homeostasis in mice.
K. Mori (2000)
10.1093/JN/116.3.429
Meal-induced changes in lipoprotein lipase activity in brown fat and other tissues of rats.
L. A. Smolin (1986)
Modulación metabólica de la oleoil estrona en ratas con sobrepeso
Romero Romero (2013)
10.21767/2573-4466.100013
Lipoprotein Lipase: A General Review
Moacir Couto de Andrade Júnior (2018)
Catabolic and Compensatory Metabolic Events in Mice during Conditions of Cachexia and Food Restriction
Kara L. Kliewer (2014)
10.1016/j.bbalip.2014.03.013
Physiological regulation of lipoprotein lipase.
S. Kersten (2014)
10.1186/1743-7075-9-10
Periodic 48 h feed withdrawal improves glucose tolerance in growing pigs by enhancing adipogenesis and lipogenesis
P. S. Mir (2012)
10.1016/S0955-2863(99)00050-9
Effects of fasting on lipoprotein lipase activity in different depots of white and brown adipose tissues in diet-induced overweight rats.
I. Lladó (1999)
10.1152/AJPREGU.2000.279.3.R1145
Weight cycling-induced alteration in fatty acid metabolism.
M. M. Sea (2000)
10.1093/JN/116.10.2000
Energy utilization in food-restricted female rats.
J. Hill (1986)
10.1016/0165-022X(88)90102-9
An improved procedure for the isolation of rat brown adipose tissue cells.
M. Vendrell (1988)
10.1016/j.nutres.2009.09.009
Feed withdrawal abate regimens lipodystrophy and metabolic syndrome symptoms, such as glucose tolerance, are associated with the diameter of retroperitoneal adipocytes in rats.
M. He (2010)
Oleoyl-oestrone inhibits lipogenic, but maintains thermogenic, gene expression of brown adipose tissue in overweight rats
Mar ´ õa (2009)
10.1016/j.mce.2020.110869
Regulation of thermogenic adipocytes during fasting and cold
Isabel Reinisch (2020)
10.1016/S1568-1254(01)80011-5
Chapter 9 Fasting and refeeding: Models of changes in metabolic efficiency
S. Brooks (2001)
10.1016/J.LIVSCI.2011.08.002
Effect of supplementation of beef steer diets with oil containing n6 and n3 fatty acids and 48 h feed withdrawal treatments on animal productivity, carcass characteristics and fatty acid composition
M. He (2011)
Semantic Scholar Logo Some data provided by SemanticScholar