Online citations, reference lists, and bibliographies.
← Back to Search

Relation Between Exercise-induced Hypertension And Sustained Hypertension In Adult Patients After Successful Repair Of Aortic Coarctation

J. Vriend, G. A. Montfrans, H. Romkes, H. Vliegen, G. Veen, J. Tijssen, B. Mulder
Published 2004 · Medicine, Mathematics

Save to my Library
Download PDF
Analyze on Scholarcy Visualize in Litmaps
Reduce the time it takes to create your bibliography by a factor of 10 by using the world’s favourite reference manager
Time to take this seriously.
Get Citationsy
Objectives To investigate whether exercise-induced hypertension in successfully repaired adult post-coarctectomy patients is associated with hypertension on 24-h blood pressure measurement and increased left ventricular mass. Methods One hundred and forty-four consecutive post-coarctectomy patients (mean age 31.5 years, range 17–74 years; mean age at repair 7.9 years, range 0–45 years) from three tertiary referral centres were studied using ambulatory blood pressure monitoring, treadmill exercise testing and echocardiography. Results Of the 144 patients, 27 (19%) were known to have sustained hypertension, based on their history, and all were on antihypertensive medication. However, 32 (27%) of the remaining 117 patients showed elevated mean daytime systolic blood pressure readings at 24-h ambulatory blood pressure monitoring (systolic blood pressure ⩾ 140 mmHg). Of the remaining 85 patients with normal mean daytime systolic blood pressure, 18 patients (21%) had exercise-induced hypertension (maximal exercise systolic blood pressure > 200 mmHg). Mean daytime systolic blood pressure was higher in the exercise-induced hypertensive patients compared to the normotensive patients with normal exercise blood pressure (134 ± 5 versus 129 ± 7 mmHg, P = 0.008). By multivariate analysis, both maximal exercise systolic blood pressure (P = 0.007) and resting systolic blood pressure (P < 0.0001) were independently associated with mean daytime systolic blood pressure. Maximal exercise systolic blood pressure had no independent predictive value for left ventricular mass (P = 0.132). Conclusions In adult post-coarctectomy patients, maximal exercise systolic blood pressure is independently associated with mean daytime systolic blood pressure at ambulatory blood pressure monitoring. In this study no independent predictive value of maximal exercise systolic blood pressure for left ventricular mass could be demonstrated.
This paper references
Systolic Hypertension During Submaximal Exercise After Correction of Coarctation of Aorta
F. James (1974)
Exercise-induced hypertension after surgical repair of coarctation of the aorta.
M. Freed (1979)
Exerciseinduced hypertension after surgical repair of coarctation of the aorta
MD Freed (1979)
Blood pressure and effect of exercise in children before and after surgical correction of coarctation of aorta.
A. Earley (1980)
Different reactivity and structure of the prestenotic and poststenotic aorta in human coarctation. Implications for baroreceptor function.
J. Sehested (1982)
Results after repair of coarctation of the aorta beyond infancy: a 10 to 28 year follow-up with particular reference to late systemic hypertension.
P. Clarkson (1983)
Increased forearm vascular reactivity in patients with hypertension after repair of coarctation.
S. Gidding (1985)
Persistent ventricular adaptations in postoperative coarctation of the aorta.
B. Kimball (1986)
Exercise in children before and after coarctectomy: hemodynamic, echocardiographic, and biochemical assessment.
A. Pelech (1986)
Exercise-induced hypertension after repair of coarctation of the aorta: arm versus leg exercise.
H. Markel (1986)
Echocardiographic assessment of left ventricular hypertrophy: comparison to necropsy findings.
R. Devereux (1986)
Long term results (15-30 years) of surgical repair of aortic coarctation.
P. Presbitero (1987)
Blood pressure at rest and during maximal dynamic and isometric exercise as predictors of systemic hypertension.
R. H. Chaney (1988)
Long-term systemic hypertension in children after successful repair of coarctation of the aorta.
R. Simsolo (1988)
Coarctation of the aorta. Long-term follow-up and prediction of outcome after surgical correction.
M. Cohen (1989)
Exaggerated pressure response to exercise in men at risk for systemic hypertension.
M. Wilson (1990)
Altered systolic and diastolic function in children after "successful" repair of coarctation of the aorta.
W. Moskowitz (1990)
Continuous wave Doppler echocardiography after surgical repair of coarctation of the aorta
K. C. Chan (1992)
Discrepancies in aortic growth explain aortic arch gradients during exercise.
H. Weber (1993)
Left ventricular diastolic dysfunction late after coarctation repair in childhood: influence of left ventricular hypertrophy.
O. Krogmann (1993)
Persistent hyperdynamic cardiovascular state at rest and during exercise in children after successful repair of coarctation of the aorta.
T. Kimball (1994)
Arterial reactivity is significantly impaired in normotensive young adults after successful repair of aortic coarctation in childhood.
H. Gardiner (1994)
Influence of age on survival, late hypertension, and recoarctation in elective aortic coarctation repair. Including long-term results after elective aortic coarctation repair with a follow-up from 25 to 44 years.
R. Brouwer (1994)
Noninvasive ambulatory 24-hour blood pressure in patients with high normal blood pressure and exaggerated systolic pressure response to exercise.
E. Lima (1995)
Exercise-induced hypertension in the arms due to impaired arterial reactivity after successful coarctation resection.
J. Günthard (1995)
Blood pressure measurement during ergometric stress testing.
I. Franz (1996)
Exercise-Induced Hypertension After Corrective Surgery for Coarctation of the Aorta
L.Ý. Sigurðóttir (1996)
Enhanced resting left ventricular filling in patients with successful coarctation repair and exercise-induced hypertension.
M. V. Tantengco (1997)
Blood Pressure Response during Treadmill Testing As a Risk Factor for New-Onset Hypertension:
Ilker Angin (1999)
Blood pressure response during treadmill testing as a risk factor for new-onset hypertension. The Framingham heart study.
J. Singh (1999)
Task force IV: Clinical use of ambulatory blood pressure monitoring. Participants of the 1999 Consensus Conference on Ambulatory Blood Pressure Monitoring.
J. Staessen (1999)
Predicting cardiovascular risk using conventional vs ambulatory blood pressure in older patients with systolic hypertension.
J. Staessen (1999)
Cardiac and Arterial Target Organ Damage in Adults with Elevated Ambulatory and Normal Office Blood Pressure
J. Liu (1999)
Systolic Hypertension in Europe Trial Investigators. Predicting cardiovascular risk using conventional and ambulatory blood pressure in older patients with systolic hypertension
JA Staessen (1999)
for the Systolic Hypertension in Europe Trial Investigators. Predicting cardiovascular risk using conventional and ambulatory blood pressure in older patients with systolic hypertension
J A Staessen (1999)
Vascular dysfunction after repair of coarctation of the aorta: Impact of Early Surgery
M. de Divitiis (2001)
Limitations of Doppler echocardiography for the post-operative evaluation of aortic coarctation.
S. De Mey (2001)
Long-term follow-up of patients after coarctation of the aorta repair.
Olga H Toro-Salazar (2002)
Prevalence of hypertension in children after early repair of coarctation of the aorta: a cohort study using casual and 24 hour blood pressure measurement
J. O'Sullivan (2002)
Blood Pressure Response to Heart Rate During Exercise Test and Risk of Future Hypertension
N. Miyai (2002)
`Reverse white-coat hypertension’ in older hypertensives
L. Wing (2002)
Exercise systolic blood pressures are of questionable value in the assessment of the adult with a previous coarctation repair
L. Swan (2003)
Exercise blood pressure in congenital heart disease and in patients after coarctation repair
M. Hauser (2003)

This paper is referenced by
Metabolic syndrome and coronary artery disease in adults with congenital heart disease.
K. Niwa (2021)
Clinical And Ambulatory Blood Pressure Monitoring In Subjects With Stent Implanted Aortic Coarctation
Nurdan Erol (2020)
Long-term observation of adults after successful repair of aortic coarctation
Beata Róg (2019)
Metabolic Syndrome in Adult Congenital Heart Disease
K. Niwa (2019)
Exercise Capacity in Asymptomatic Adult Patients Treated for Coarctation of the Aorta
E. J. Dijkema (2019)
Hypertensive Response With Exercise to Reveal Increased Cardiovascular Risk in Adults With Aortic Coarctation Repair: Value and Caution.
P. Millar (2018)
A systematic review and meta-analysis of exercise and exercise hypertension in patients with aortic coarctation
H. Foulds (2017)
Hypertension in Coarctation of the Aorta: Challenges in Diagnosis in Children
T. Vigneswaran (2017)
The study of left ventricular hypertrophy in ECG and QT dispersion in marathon runner with exercise-induced hypertension.
Shun-Zhe Piao (2015)
Heart failure caused by congenital left-sided lesions.
E. Krieger (2014)
A prospective observational multicenter study of balloon angioplasty for the treatment of native and recurrent coarctation of the aorta
K. C. Harris (2014)
Congenital and Inflammatory Arteritides
B. Greco (2014)
Aortic coarctation: late complications and treatment strategies
P. Luijendijk (2014)
Usefulness of cardiopulmonary exercise testing to predict the development of arterial hypertension in adult patients with repaired isolated coarctation of the aorta.
R. Buys (2013)
Long-term follow-up after aortic coarctation repair: the unsolved issue of exercise-induced hypertension.
A. Correia (2013)
Correlation of exercise response in repaired coarctation of the aorta to left ventricular mass and geometry.
E. Krieger (2013)
Hypertension after repair of aortic coarctation--a systematic review.
C. Canniffe (2013)
Rationale and design of a trial on the effect of high dose statins on cardiovascular risk in adults after successful coarctation repair.
P. Luijendijk (2012)
Initial and six-year results of stent implantation for aortic coarctation in children.
B. Thanopoulos (2012)
Surgical versus percutaneous treatment of aortic coarctation: new standards in an era of transcatheter repair
P. Luijendijk (2012)
Coarctation of the Aorta Stent Trial (COAST): study design and rationale.
R. Ringel (2012)
Late morbidity after repair of aortic coarctation.
T. Pedersen (2012)
Comparison of surgical, stent, and balloon angioplasty treatment of native coarctation of the aorta: an observational study by the CCISC (Congenital Cardiovascular Interventional Study Consortium).
T. Forbes (2011)
Usefulness of exercise-induced hypertension as predictor of chronic hypertension in adults after operative therapy for aortic isthmic coarctation in childhood.
P. Luijendijk (2011)
Augmentation of central arterial pressure in adult patients after coarctation repair
L. Szczepaniak-Chicheł (2011)
Hypertension and coarctation of the aorta: an inevitable consequence of developmental pathophysiology
D. Kenny (2011)
Therapy refractory hypertension in adults: aortic coarctation has to be ruled out
M. Hemels (2011)
Coarctation of the aorta: from fetal life to adulthood.
D. Kenny (2011)
High long-term morbidity in repaired aortic coarctation: weak association with residual arch obstruction.
T. Pedersen (2011)
Treatment of congenital heart disease: risk-reducing measures in young adults.
T. van der Bom (2011)
Aortic stent implantation in the isthmic region in an animal model to investigate pathophysiology and treatment of human aortic coarctation
L. Semplicini (2010)
Parameters of arterial function and structure in adult patients after coarctation repair
O. Trojnarska (2010)
See more
Semantic Scholar Logo Some data provided by SemanticScholar