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Survival Of Malignant Pleural Mesothelioma Cases In The Tuscan Mesothelioma Register, 1988–2000: A Population-based Study
G. Gorini, G. De Gregorio, S. Silvestri, E. Chellini, V. Cupelli, A. Seniori Costantini
Published 2005 · Medicine
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This study analyses survival of Tuscan residents (Italy, 3.5 million population) diagnosed by histological examination with malignant pleural mesothelioma (MPM) during the period 1988–2000, and recorded in the Tuscan Malignant Mesothelioma Register. The aim was to establish the prognostic role of demographic, diagnostic and asbestos exposure variables. During 1988–2000, 381 MPM cases were recorded (318 men; 63 women). Vital status was ascertained up to 31 December 2002. No cases were lost to follow-up. Median survival of certain MPM was 324 days (11 months; 95% CI 297–366); 45.7% (95% CI 40.6–50.6%) survived more than 1 year; 24.2% (95% CI 20.0–28.5%) more than 2 years. In univariate and multivariate analyses survival was associated with histological subtype (epithelioid subtype had the longest survival). Gender, age, period of diagnosis, hospital of diagnosis and asbestos exposure did not show significant effects. Therapeutic information was available for patients of the period 1997–2000. There was no significant difference in survival between treated versus untreated patients. In conclusion, no advance in prognosis at the population level in the most recent period can be suggested on the basis of the data available to the Tuscan Malignant Mesothelioma Register.
This paper references
Malignant pleural mesothelioma: a disease unaffected by current therapeutic maneuvers.
A. Alberts (1988)
The management of malignant pleural mesothelioma; single centre experience in 10 years.
T. Aziz (2002)
Cancer incidence in five continents. Volume VIII.
Diffuse malignant mesothelioma of the pleura in Ontario and Quebec: a retrospective study of 332 patients.
P. Ruffié (1989)
Diffuse malignant mesothelioma of pleura: Diagnosis and survival in 92 cases
V. Adams (1986)
The EUROCARE II study
F. Berrino (1998)
[Malignant pleural mesothelioma incidence and mortality in Tuscany in 1988-1999].
G. Gorini (2003)
Survival after Pleural Malignant Mesothelioma a Population-based Study in Italy
C. Magnani (2002)
Prognostic factors in diffuse malignant pleural mesothelioma. A study of 167 patients.
E. Chailleux (1988)
Factors influencing long-term survival in mesothelioma patients—results of the German mesothelioma register
V. Neumann (2004)
Analysis of survival of mesothelioma cases in the Italian register (ReNaM).
A. Marinaccio (2003)
The European mesothelioma epidemic
J. Peto (1999)
Prognostic factors for malignant mesothelioma in 142 patients: validation of CALGB and EORTC prognostic scoring systems
J. Edwards (2000)
DIFFUSE MALIGNANT MESOTHELIOMA OF THE PLEURA.
F. Manfredi (1965)
Malignant mesothelioma: prognostic variables in a registry of 180 patients, the Dana-Farber Cancer Institute and Brigham and Women's Hospital experience over two decades, 1965-1985.
K. Antman (1988)
Survival patterns for malignant mesothelioma: The seer experience
R. Spirtas (1988)
Features of asbestos-exposed and unexposed mesothelioma.
A. Hirsch (1982)
Diagnosis and prognostic factors in malignant pleural mesothelioma: a retrospective analysis of 65 patients
L Tammilehto (1992)
Prognostic factors of malignant mesothelioma of the pleura.
A. Anand (1994)
Trends in mortality from primary pleural tumors and incidence of pleural mesothelioma in Italy: a very serious situation
E Merler (1999)
Prognostic factors of malignant mesothelioma of the pleura
V. de Pangher Manzini (1993)
Malignant mesothelioma: experience at the Singapore General Hospital.
K. Chan (2003)
[Malignant mesothelioma in Basse-Normandie, a French population study. Descriptive analysis, prognostic factors and survival].
N. Desoubeaux (2001)
Malignant mesothelioma – German mesothelioma register 1987–1999
V. Neumann (2001)
Evidence for longer survival of patients with pleural mesothelioma without asbestos exposure.
M. Law (1983)
Radical surgery for mesothelioma
T. Treasure (2004)
[Tuscany mesothelioma registry (1988-2000): evaluation of asbestos exposure].
G. Gorini (2002)
Increased but low incidence and poor survival of malignant mesothelioma in the southeastern part of The Netherlands since 1970: a population-based study.
M. Janssen-Heijnen (1999)
Prognostic factors and survival in malignant pleural mesothelioma.
T. van Gelder (1994)
Important prognostic factors in patients with malignant pleural mesothelioma, managed surgically.
V. Rusch (1999)
Malignant pleural mesothelioma: a disease unaffected by current therapeutic manoeuvres
AS Alberts (1988)
Malignant mesothelioma in Italy, 1997.
M. Nesti (2004)
Factors predictive of survival among 337 patients with mesothelioma treated between 1984 and 1994 by the Cancer and Leukemia Group B.
J. Herndon (1998)
Diffuse malignant mesothelioma. Prospective evaluation of 69 patients.
A. Chahinian (1982)
Is the ratio of pleural mesothelioma mortality to pleural cancer mortality approximately unity for Italy? Considerations from the oldest regional mesothelioma register in Italy
G. Gorini (2002)
Diagnosis and prognostic factors in malignant pleural mesothelioma: a retrospective analysis of sixty-five patients.
L. Tammilehto (1992)
Thoracoscopy in pleural malignant mesothelioma: A prospective study of 188 consecutive patients. Part 2: Prognosis and staging
C. Boutin (1993)
This paper is referenced by
Effects of combined therapies on the survival of pleural mesothelioma patients treated in Brescia, 1982-2006.
P. Barbieri (2012)
Clinical Features and Treatment Outcome of Malignant Pleural Mesothelioma
M. Mencoboni (2017)
Survival of pleural malignant mesothelioma in Italy: A population‐based study
F. Montanaro (2009)
Sarcomatoid neoplasms of the lung and pleura.
W. Travis (2010)
Predicting survival in malignant mesothelioma
A. Musk (2011)
Effects of Combined Therapies on the Survival of Pleural Mesothelioma Patients Treated in Brescia, 1982–2006
Pietro Gino Barbieri (2012)
Effects of treatment regimens on survival in patients with malignant pleural mesothelioma.
A. Abakay (2013)
Malignant mesothelioma: a clinical study of 238 cases.
Steven E. Haber (2011)
A Clinical, Radiographic and Laboratory Evaluation of Prognostic Factors in 363 Patients with Malignant Pleural Mesothelioma
A. C. Tanrıkulu (2010)
SAHİBİ VE SORUMLU MÜDÜR/ OWNER AND RESPONSIBLE MANAGER
Bahaüddin ÇOLAKOĞLU (2018)
The incidence of mesothelioma has not decreased for the last twenty years in Southeast region of Anatolia.
A. I. Carkanat (2011)
Impact of mesothelioma histologic subtype on outcomes in the Surveillance, Epidemiology, and End Results database.
R. Meyerhoff (2015)
Regulation of sex hormone receptors in sexual dimorphism of human cancers.
Daoshan Zheng (2018)
Prognostic factors in malignant pleural mesothelioma: a retrospective study of 60 Turkish patients.
A. Koyuncu (2015)
A Novel Prospective Study Assessing the Combination of Photodynamic Therapy and Proton Radiation Therapy: Safety and Outcomes When Treating Malignant Pleural Mesothelioma
S. Rice (2019)
A. Binazzi (2016)
MALIGN PLEVRAL MEZOTELYOMA AYIRICI TANISI VE PROGNOZUNDA 18F-FDG PET/BT’NİN ROLÜ
D. Şimşek (2019)
Reliability of Family Proxy Data for Studies of Malignant Mesothelioma: Results from the ATSDR Pilot Surveillance
N. Melnikova (2013)
Malignant Pleural Mesothelioma: A Population-Based Study of Survival
M. Milano (2010)
Malignant Mesothelioma: Pathology
S. Anttila (2014)
Relationship between 18 FDG PET-CT findings and the survival of 177 patients with malignant pleural mesothelioma.
A. Abakay (2013)