Online citations, reference lists, and bibliographies.
← Back to Search

Survival Of Malignant Pleural Mesothelioma Cases In The Tuscan Mesothelioma Register, 1988–2000: A Population-based Study

G. Gorini, G. De Gregorio, S. Silvestri, E. Chellini, V. Cupelli, A. Seniori Costantini
Published 2005 · Medicine

Cite This
Download PDF
Analyze on Scholarcy
Share
This study analyses survival of Tuscan residents (Italy, 3.5 million population) diagnosed by histological examination with malignant pleural mesothelioma (MPM) during the period 1988–2000, and recorded in the Tuscan Malignant Mesothelioma Register. The aim was to establish the prognostic role of demographic, diagnostic and asbestos exposure variables. During 1988–2000, 381 MPM cases were recorded (318 men; 63 women). Vital status was ascertained up to 31 December 2002. No cases were lost to follow-up. Median survival of certain MPM was 324 days (11 months; 95% CI 297–366); 45.7% (95% CI 40.6–50.6%) survived more than 1 year; 24.2% (95% CI 20.0–28.5%) more than 2 years. In univariate and multivariate analyses survival was associated with histological subtype (epithelioid subtype had the longest survival). Gender, age, period of diagnosis, hospital of diagnosis and asbestos exposure did not show significant effects. Therapeutic information was available for patients of the period 1997–2000. There was no significant difference in survival between treated versus untreated patients. In conclusion, no advance in prognosis at the population level in the most recent period can be suggested on the basis of the data available to the Tuscan Malignant Mesothelioma Register.
This paper references
10.1200/JCO.1988.6.3.527
Malignant pleural mesothelioma: a disease unaffected by current therapeutic maneuvers.
A. Alberts (1988)
10.1016/S1010-7940(02)00273-7
The management of malignant pleural mesothelioma; single centre experience in 10 years.
T. Aziz (2002)
Cancer incidence in five continents. Volume VIII.
(2002)
10.1200/JCO.1989.7.8.1157
Diffuse malignant mesothelioma of the pleura in Ontario and Quebec: a retrospective study of 332 patients.
P. Ruffié (1989)
10.1002/1097-0142(19861001)58:7<1540::AID-CNCR2820580727>3.0.CO;2-5
Diffuse malignant mesothelioma of pleura: Diagnosis and survival in 92 cases
V. Adams (1986)
10.1016/S0959-8049(98)00334-7
The EUROCARE II study
F. Berrino (1998)
[Malignant pleural mesothelioma incidence and mortality in Tuscany in 1988-1999].
G. Gorini (2003)
10.1177/030089160208800403
Survival after Pleural Malignant Mesothelioma a Population-based Study in Italy
C. Magnani (2002)
10.1378/CHEST.93.1.159
Prognostic factors in diffuse malignant pleural mesothelioma. A study of 167 patients.
E. Chailleux (1988)
10.1007/S00420-003-0498-6
Factors influencing long-term survival in mesothelioma patients—results of the German mesothelioma register
V. Neumann (2004)
10.1016/S0959-8049(03)00233-8
Analysis of survival of mesothelioma cases in the Italian register (ReNaM).
A. Marinaccio (2003)
10.1038/sj.bjc.6690105
The European mesothelioma epidemic
J. Peto (1999)
10.1136/thorax.55.9.731
Prognostic factors for malignant mesothelioma in 142 patients: validation of CALGB and EORTC prognostic scoring systems
J. Edwards (2000)
DIFFUSE MALIGNANT MESOTHELIOMA OF THE PLEURA.
F. Manfredi (1965)
10.1200/JCO.1988.6.1.147
Malignant mesothelioma: prognostic variables in a registry of 180 patients, the Dana-Farber Cancer Institute and Brigham and Women's Hospital experience over two decades, 1965-1985.
K. Antman (1988)
10.1002/IJC.2910410409
Survival patterns for malignant mesothelioma: The seer experience
R. Spirtas (1988)
10.1002/AJIM.4700030407
Features of asbestos-exposed and unexposed mesothelioma.
A. Hirsch (1982)
Diagnosis and prognostic factors in malignant pleural mesothelioma: a retrospective analysis of 65 patients
L Tammilehto (1992)
10.1002/1097-0142(19930715)72:2<410::AID-CNCR2820720216>3.0.CO;2-G
Prognostic factors of malignant mesothelioma of the pleura.
A. Anand (1994)
Trends in mortality from primary pleural tumors and incidence of pleural mesothelioma in Italy: a very serious situation
E Merler (1999)
10.1002/1097-0142(19930715)72:2<410::aid-cncr2820720216>3.0.co;2-g
Prognostic factors of malignant mesothelioma of the pleura
V. de Pangher Manzini (1993)
Malignant mesothelioma: experience at the Singapore General Hospital.
K. Chan (2003)
[Malignant mesothelioma in Basse-Normandie, a French population study. Descriptive analysis, prognostic factors and survival].
N. Desoubeaux (2001)
10.1007/S004200100240
Malignant mesothelioma – German mesothelioma register 1987–1999
V. Neumann (2001)
10.1136/thx.38.10.744
Evidence for longer survival of patients with pleural mesothelioma without asbestos exposure.
M. Law (1983)
10.1136/BMJ.328.7434.237
Radical surgery for mesothelioma
T. Treasure (2004)
[Tuscany mesothelioma registry (1988-2000): evaluation of asbestos exposure].
G. Gorini (2002)
10.1097/00008469-199908000-00007
Increased but low incidence and poor survival of malignant mesothelioma in the southeastern part of The Netherlands since 1970: a population-based study.
M. Janssen-Heijnen (1999)
Prognostic factors and survival in malignant pleural mesothelioma.
T. van Gelder (1994)
10.1016/S0003-4975(99)01038-3
Important prognostic factors in patients with malignant pleural mesothelioma, managed surgically.
V. Rusch (1999)
Malignant pleural mesothelioma: a disease unaffected by current therapeutic manoeuvres
AS Alberts (1988)
10.1002/AJIM.10313
Malignant mesothelioma in Italy, 1997.
M. Nesti (2004)
10.1378/CHEST.113.3.723
Factors predictive of survival among 337 patients with mesothelioma treated between 1984 and 1994 by the Cancer and Leukemia Group B.
J. Herndon (1998)
10.7326/0003-4819-96-6-746
Diffuse malignant mesothelioma. Prospective evaluation of 69 patients.
A. Chahinian (1982)
10.1038/sj.bjc.6600363
Is the ratio of pleural mesothelioma mortality to pleural cancer mortality approximately unity for Italy? Considerations from the oldest regional mesothelioma register in Italy
G. Gorini (2002)
10.1159/000196043
Diagnosis and prognostic factors in malignant pleural mesothelioma: a retrospective analysis of sixty-five patients.
L. Tammilehto (1992)
10.1002/1097-0142(19930715)72:2<394::AID-CNCR2820720214>3.0.CO;2-5
Thoracoscopy in pleural malignant mesothelioma: A prospective study of 188 consecutive patients. Part 2: Prognosis and staging
C. Boutin (1993)



This paper is referenced by
10.1700/1088.11932
Effects of combined therapies on the survival of pleural mesothelioma patients treated in Brescia, 1982-2006.
P. Barbieri (2012)
10.1159/000464410
Clinical Features and Treatment Outcome of Malignant Pleural Mesothelioma
M. Mencoboni (2017)
10.1002/ijc.23874
Survival of pleural malignant mesothelioma in Italy: A population‐based study
F. Montanaro (2009)
10.1043/2010-0086-RAR.1
Sarcomatoid neoplasms of the lung and pleura.
W. Travis (2010)
10.1183/09031936.00000811
Predicting survival in malignant mesothelioma
A. Musk (2011)
10.1177/030089161209800206
Effects of Combined Therapies on the Survival of Pleural Mesothelioma Patients Treated in Brescia, 1982–2006
Pietro Gino Barbieri (2012)
Effects of treatment regimens on survival in patients with malignant pleural mesothelioma.
A. Abakay (2013)
10.2486/INDHEALTH.MS1147
Malignant mesothelioma: a clinical study of 238 cases.
Steven E. Haber (2011)
10.1159/000321370
A Clinical, Radiographic and Laboratory Evaluation of Prognostic Factors in 363 Patients with Malignant Pleural Mesothelioma
A. C. Tanrıkulu (2010)
SAHİBİ VE SORUMLU MÜDÜR/ OWNER AND RESPONSIBLE MANAGER
Bahaüddin ÇOLAKOĞLU (2018)
The incidence of mesothelioma has not decreased for the last twenty years in Southeast region of Anatolia.
A. I. Carkanat (2011)
10.1016/j.jss.2015.01.043
Impact of mesothelioma histologic subtype on outcomes in the Surveillance, Epidemiology, and End Results database.
R. Meyerhoff (2015)
10.1016/j.canlet.2018.09.001
Regulation of sex hormone receptors in sexual dimorphism of human cancers.
Daoshan Zheng (2018)
10.4103/0973-1482.138094
Prognostic factors in malignant pleural mesothelioma: a retrospective study of 60 Turkish patients.
A. Koyuncu (2015)
10.1111/php.13065
A Novel Prospective Study Assessing the Combination of Photodynamic Therapy and Proton Radiation Therapy: Safety and Outcomes When Treating Malignant Pleural Mesothelioma
S. Rice (2019)
SENTIERI-ReNaM: Risultati
A. Binazzi (2016)
10.26650/iuitfd.2019.0019
MALIGN PLEVRAL MEZOTELYOMA AYIRICI TANISI VE PROGNOZUNDA 18F-FDG PET/BT’NİN ROLÜ
D. Şimşek (2019)
10.1155/2013/325409
Reliability of Family Proxy Data for Studies of Malignant Mesothelioma: Results from the ATSDR Pilot Surveillance
N. Melnikova (2013)
10.1097/JTO.0b013e3181f1cf2b
Malignant Pleural Mesothelioma: A Population-Based Study of Survival
M. Milano (2010)
10.1007/978-1-4471-2825-0_16
Malignant Mesothelioma: Pathology
S. Anttila (2014)
Relationship between 18 FDG PET-CT findings and the survival of 177 patients with malignant pleural mesothelioma.
A. Abakay (2013)
Semantic Scholar Logo Some data provided by SemanticScholar