Online citations, reference lists, and bibliographies.

The Contribution Of Family History To Hearing Loss In An Older Population

C. McMahon, A. Kifley, E. Rochtchina, P. Newall, P. Mitchell
Published 2008 · Medicine

Cite This
Download PDF
Analyze on Scholarcy
Share
Objectives: Although it has been well established that the prevalence of and severity of hearing loss increase with age, the contribution of familial factors to age-related hearing loss cannot be quantified. This is largely because hearing loss in older people has both genetic and environmental contributions. As environmental factors play an increasing role with age, it is difficult to delineate the separate contribution of genetic factors to age-related hearing loss. In a population-based survey of hearing loss in a representative older Australian community, we attempted to overcome this using logistic regression analysis, accounting for known factors associated with hearing loss including age, sex, noise exposure at work, diabetes, and current smoking. Design: We tested hearing thresholds using pure tone audiometry and used a forced choice questionnaire to determine the nature of family history in a population of individuals aged 50 yrs or older in a defined region, west of Sydney, Australia (N = 2669). We compared the characteristics of participants with and without family history of hearing loss. Of those reporting a positive family history, we compared subgroups for age, gender and severity of hearing loss, and trends by the severity of hearing loss. Logistic regression was used to obtain odds ratios (ORs) with 95% confidence intervals (CIs) that compared the chances of having hearing loss in participants with and without family history, after adjusting for other factors known associated with hearing loss. Results: Our findings indicate that family history was most strongly associated with moderate to severe age-related hearing loss. We found a strong association between maternal family history of hearing loss and moderate to severe hearing loss in women (adjusted OR 3.0; 95% CI 1.6-5.6 in women with without a maternal history). Paternal family history of hearing loss was also significantly, though less strongly, associated with moderate-severe hearing loss in men (adjusted OR 2.0; CI 1.01-3.9 in men with than without a paternal history). Conclusions: Findings from this study are important in the identification of individuals whose auditory system may be genetically susceptible to aging and environmental insult. Genetic counseling may assist in ameliorating the effects of hearing loss.
This paper references
10.3109/01050399709074981
Hearing in the elderly > or = 80 years of age. Prevalence of problems and sensitivity.
A. Parving (1997)
Effects of folic acid supplementation on hearing in older adults: a randomized, controlled trial
Durga (2007)
10.1017/S0266462300103162
The societal costs of severe to profound hearing loss in the United States.
P. E. Mohr (2000)
10.1093/OXFORDJOURNALS.AJE.A009713
Prevalence of hearing loss in older adults in Beaver Dam, Wisconsin. The Epidemiology of Hearing Loss Study.
K. Cruickshanks (1998)
10.1017/S0022215100108345
Hearing threshold in patients with diabetes mellitus.
M. Kurien (1989)
10.1093/GERONA/62.4.447
Genetic and environmental influences on hearing in older women.
A. Viljanen (2007)
10.3109/01050399309046025
Epidemiology of hearing disorders. Some factors affecting hearing. The Copenhagen Male Study.
A. Parving (1993)
10.1007/PL00000673
Mitochondrial defects and hearing loss
T. Hutchin (2000)
10.1001/ARCHOTOL.125.6.654
Genetic associations in age-related hearing thresholds.
G. Gates (1999)
10.1046/J.1532-5415.2001.4911245.X
Genetic and environmental influences on self-reported reduced hearing in the old and oldest old.
K. Christensen (2001)
Listen hear! the economic impact and cost of hearing loss in Australia
A. Economics (2006)
Hearing in adults
A. Davis (1995)
10.1002/ajmg.1320460504
Genetic epidemiological studies of early-onset deafness in the U.S. school-age population.
M. Marazita (1993)
Noise and bloodpressure [ letter ]
J. M. Tielsch (1977)
10.1080/01050390152704751
Age and noise-induced hearing loss
E. Toppila (2001)
10.1111/j.1749-6632.1991.tb19572.x
Genetic epidemiology of hearing impairment.
N. Morton (1991)
Family History and Risk of Primary Open Angle Glaucoma
J. Tielsch (2010)
10.1093/ije/18.4.911
The prevalence of hearing impairment and reported hearing disability among adults in Great Britain.
A. Davis (1989)
10.1002/ajmg.1320540211
Genetic epidemiologic study of hearing loss in an adult population.
A. Sill (1994)
10.1080/010503999424897
Prevalence of hereditary hearing impairment in adults.
Y. Sakihara (1999)
10.1001/archopht.1994.01090130079022
Family history and risk of primary open angle glaucoma. The Baltimore Eye Survey.
J. Tielsch (1994)
10.1001/JAMA.279.21.1715
Cigarette smoking and hearing loss: the epidemiology of hearing loss study.
K. Cruickshanks (1998)
10.1016/S0378-5955(01)00250-7
Genetic basis for susceptibility to noise-induced hearing loss in mice
R. Davis (2001)
10.1097/00003446-199704000-00003
Description and Primary Results from an Audiometric Study of Male Twins
K. Karlsson (1997)
Accuracy and implications of a reported family history of glaucoma: experience from the Glaucoma Inheritance Study in Tasmania.
A. McNaught (2000)
Noise and bloodpressure
J Takala (1977)
10.1016/S1359-6446(05)03595-6
Keynote review: The auditory system, hearing loss and potential targets for drug development.
M. Holley (2005)
10.1093/IJE/30.6.1371
Validation of self-reported hearing loss. The Blue Mountains Hearing Study.
D. Sindhusake (2001)
10.1076/opep.9.5.333.10335
Bias in self-reported family history and relationship to glaucoma: The Blue Mountains Eye Study
P. Mitchell (2002)
10.1016/S0140-6736(73)92643-3
Letter: Mentally subnormal children and their families.
M. Davis (1973)
10.1097/00003446-199008000-00001
Hearing in the elderly: the Framingham cohort, 1983-1985. Part I. Basic audiometric test results.
G. Gates (1990)
10.1016/S0140-6736(77)90908-4
NOISE AND BLOOD-PRESSURE
J. Takala (1977)



This paper is referenced by
10.1016/B978-0-12-415994-5.00008-7
Noise and the Aging Brain
Jos J. Eggermont (2014)
10.1097/AUD.0000000000000610
Heritability of Age-Related Hearing Loss in Middle-Aged and Elderly Chinese: A Population-Based Twin Study
Haiping Duan (2019)
10.1016/j.heares.2010.03.007
Heritability of audiometric shape parameters and familial aggregation of presbycusis in an elderly Flemish population
Kelly Demeester (2010)
10.1155/2013/308509
The Need for Improved Detection and Management of Adult-Onset Hearing Loss in Australia
C. McMahon (2013)
10.1136/bmj.g2984
A 68 year old woman with deteriorating hearing
Natalie Ronan (2014)
Considerations in designing an adult hearing screening programme
Anouk M Linssen (2015)
10.1159/000444561
Hearing Loss in Older Age and Its Effect on the Individuals, Their Families and the Community
Catherine M. McMahon (2016)
10.1016/j.lfs.2018.01.015
Polymorphisms in folate metabolism genes are associated with susceptibility to presbycusis
S. Manche (2018)
Screening for Hearing Loss in Adults Ages 50 Years and Older
R. Chou (2011)
10.4102/sajcd.v63i1.105
The prevalence of hearing impairment within the Cape Town Metropolitan area
L. Ramma (2016)
10.1007/978-3-642-23499-6_406
Gastroesophageal Reflux in Children
Samra Sarigol Blanchard (2013)
10.5606/kbbihtisas.2015.10179
Etiological classification of presbycusis in Turkish population according to audiogram configuration.
Kamil Hakan Kaya (2015)
10.1007/978-3-030-06200-2_13
Sensory Health and Healthy Aging: Hearing and Smell
Denis C. Lafreniere (2019)
FATORES DE RISCO PARA PERDA AUDITIVA EM IDOSOS Risk factors for hearing loss in elderly
Martins Kvc (2012)
10.1002/lary.28646
Genetics of Postlingual Sensorineural Hearing Loss.
S. Ahmadmehrabi (2020)
10.1177/0194599810395079
Challenges and Opportunities in Presbycusis
Kourosh Parham (2011)
10.31338/uw.9788323538578.pp.93-118
STARZENIE SIĘ SŁUCHU
Wirginia Likus (2019)
Exploring risk factors associated with potential hearing loss in Namibian Class A mines
Irene M. Barrion (2015)
Age Related Hearing Loss: Social and Emotional Impact Clinical Study
Sofia Paiva (2017)
10.1016/j.heares.2019.107875
Evidence for gene-smoking interactions for hearing loss and deafness in Japanese American families
Jia Y Wan (2020)
A QUALIDADE DE VIDA NO INDIVÍDUO COM PERDA AUDITIVA
P. Jorge (2011)
Hearing among older adults–an epidemiological study
Oulu F Inland (2011)
10.1097/AUD.0b013e3181e85614
Impact of Laser Eustachian Tuboplasty on Middle Ear Ventilation, Hearing, and Tinnitus in Chronic Tube Dysfunction
Philipp P. Caffier (2011)
10.1007/s00405-010-1270-7
Age-related hearing loss or presbycusis
Q. Huang (2010)
10.5124/JKMA.2011.54.9.918
Age-related hearing loss and the effects of hearing aids
Jeesun Choi (2011)
REVIEW ON AGE RELATED SENSORI-NEURAL DEAFNESS (BADHIRYA) AND IT’S AYURVEDIC APPROACH
Gajanan B. Patil (2016)
Age-related hearing loss and neurocognitive function: Normal and pathological processes in cognitive ageing
David Loughrey (2018)
Hearing Impairment and Tinnitus in the Elderly
J. Salonen (2013)
10.21522/TIJCR.2014.03.01.Art016
Determination of relationship and frequency of sensorineural hearing loss in previously diagnosed diabetes mellitus and/or hypertensive adults using qualitative semi-structured interviews
Amrit Bhalchandra Karmarkar (2016)
A Combination Antioxidant Therapy in the Treatment and Prevention of Age Related Hearing Loss
Selena Heman-Ackah (2015)
10.1055/s-0039-3402442
Precochlear Implant Assessment: Clinical Profile and Family History of Children with Severe Bilateral Prelingual Hearing Loss
Syed Hashim Raza (2020)
Risk factors for hearing loss in elderly
Kelly Vasconcelos Chaves Martins (2012)
See more
Semantic Scholar Logo Some data provided by SemanticScholar